[{"data":1,"prerenderedAt":169},["ShallowReactive",2],{"drug-chlordiazepoxide-clidinium":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":23,"regimens":46,"contraindications":70,"warnings":89,"renal":90,"monitoring":91,"interactions":92,"review":93,"examples":96,"atc":102,"iran":104,"links":120,"populations":137,"usApproval":164},"chlordiazepoxide-clidinium",1,{"fa":7,"en":8},"کلیدینیوم-سی (لیبراکس)","Chlordiazepoxide\u002Fclidinium","alimentary-metabolism",{"fa":11,"en":12},"ضداسپاسم + بنزودیازپین","Antispasmodic + benzodiazepine",[14],{"name":15,"market":16},"Librax","US",[18,19,20,21,22],"librax","لیبراکس","کلیدینیوم سی","کلیدینیوم","chlordiazepoxide clidinium",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"components":32,"markets":41,"refs":42},"cap","capsule","oral","Chlordiazepoxide 5 mg + clidinium 2.5 mg capsule",{"amount":30,"unit":31,"perUnit":26},5,"mg",{"chlordiazepoxide":33,"clidinium":37},{"name":34,"amount":30,"unit":31},{"fa":35,"en":36},"کلردیازپوکساید","Chlordiazepoxide",{"name":38,"amount":40,"unit":31},{"fa":21,"en":39},"Clidinium",2.5,[16],[43],{"source":44,"section":45},"fda-librax","How Supplied",[47],{"id":48,"disease":48,"label":49,"population":52,"type":56,"unit":31,"dose":57,"refs":59,"doseComponent":62,"notes":63},"ibs",{"fa":50,"en":51},"IBS\u002Fزخم پپتیک (کمکی) — شروع حداکثر ۲ کپسول در روز","IBS\u002Fpeptic ulcer (adjunct) — start no more than 2 capsules daily",{"minAge":53},{"value":54,"unit":55},18,"year","fixed",{"perDose":30,"dosesPerDay":58},2,[60],{"source":44,"section":61},"Dosage and Administration","chlordiazepoxide",[64],{"text":65,"refs":68},{"fa":66,"en":67},"افزایش تدریجی در صورت نیاز و تحمل. سالمندان در معرض عوارض بیشتر.","Increase gradually as needed and tolerated. Elderly at greater risk of adverse reactions.",[69],{"source":44,"section":61},[71,80],{"id":72,"severity":73,"text":74,"refs":77},"ci","block",{"fa":75,"en":76},"گلوکوم؛ هیپرتروفی پروستات و انسداد گردن مثانه؛ حساسیت.","Glaucoma; prostatic hypertrophy and bladder-neck obstruction; hypersensitivity.",[78],{"source":44,"section":79},"Contraindications",{"id":81,"severity":82,"text":83,"refs":86},"boxed","warn",{"fa":84,"en":85},"هشدار جعبه‌ای: مصرف همزمان با اپیوئیدها؛ سوءمصرف و وابستگی؛ ترک با قطع ناگهانی.","Boxed warning: concomitant opioids; abuse and dependence; withdrawal on abrupt stop.",[87],{"source":44,"section":88},"Boxed Warning",[],[],[],[],{"status":94,"reviewer":95,"date":95},"unverified",null,[97],{"regimen":48,"formulation":25,"input":98,"expect":101},{"ageYears":99,"weightKg":100},40,70,{"perDose":30,"tabletsPerDoseRounded":5},[103],"A03CA02",{"status":105,"forms":106,"refs":115},"registered",[107,111],{"code":108,"en":109,"fa":110},"00267","CHLORDIAZEPOXIDE 10MG TAB","قرص کلردیازپوکساید ۱۰ میلی‌گرم",{"code":112,"en":113,"fa":114},"00268","CHLORDIAZEPOXIDE 5MG TAB","قرص کلردیازپوکساید ۵ میلی‌گرم",[116],{"source":117,"section":118,"url":119},"darooyab-generic","G-1246\u002FChlordiazepoxide","https:\u002F\u002Fwww.darooyab.ir\u002FG-1246\u002FChlordiazepoxide",[121,125,129,132,135],{"kind":122,"url":123,"label":124},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=212344","ANDA212344",{"kind":126,"url":127,"label":128},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=87d1a147-d3c3-4097-aac0-4b19c49eabe3","FDA Librax (generic)",{"kind":130,"url":131,"label":36},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682078.html",{"kind":133,"url":134,"label":103},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A03CA02",{"kind":136,"url":119,"label":36},"darooyab",{"pregnancy":138,"pediatric":147,"geriatric":156},{"level":139,"text":140,"quote":143,"refs":144},"caution",{"fa":141,"en":142},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","An increased risk of congenital malformations associated with the use of minor tranquilizers (chlordiazepoxide, diazepam and meprobamate) during the first trimester of pregnancy has been suggested in several studies.",[145],{"source":44,"section":146},"Precautions\u002FWarnings – Usage in Pregnancy",{"level":148,"text":149,"quote":152,"refs":153},"not-established",{"fa":150,"en":151},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[154],{"source":44,"section":155},"Pediatric Use",{"level":139,"text":157,"quote":160,"refs":161},{"fa":158,"en":159},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Dosing in geriatric subjects should be initiated cautiously (no more than 2 capsules per day) and increased gradually if needed and tolerated (see DOSAGE AND ADMINISTRATION ).",[162],{"source":44,"section":163},"Geriatric Use",{"kind":165,"refs":166,"id":124},"ANDA",[167],{"source":44,"section":168},"SPL approval \u002F marketing category",1792191865258]