[{"data":1,"prerenderedAt":194},["ShallowReactive",2],{"drug-ciprofloxacin-otic":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":34,"contraindications":60,"warnings":80,"renal":81,"monitoring":82,"interactions":83,"review":84,"examples":87,"atc":93,"iran":95,"links":139,"populations":154,"usApproval":189},"ciprofloxacin-otic",1,{"fa":7,"en":8},"قطره گوش سیپروفلوکساسین","Ciprofloxacin ear drops","sensory-organs",{"fa":11,"en":12},"فلوروکینولون موضعی گوش","Topical otic fluoroquinolone",[14],{"name":15,"market":16},"Cetraxal","US",[18,19,20],"cetraxal","قطره گوش سیپرو","سیپروفلوکساسین گوش",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":29,"refs":30},"otic-0-2","drops","topical","0.2% single-dose container (0.25 mL)",{"amount":5,"unit":28,"perVolumeMl":5},"mL",[16],[31],{"source":32,"section":33},"fda-cetraxal","3",[35],{"id":36,"disease":37,"label":38,"population":41,"type":44,"unit":28,"dose":45,"refs":48,"durationDays":51,"notes":53},"oe","otitis-externa",{"fa":39,"en":40},"عفونت گوش خارجی — ۱ سال به بالا: یک ویال ۰٫۲۵ mL دو بار، ۷ روز","Otitis externa — ≥1 y: one 0.25 mL single-dose container twice daily for 7 days",{"minAge":42},{"value":5,"unit":43},"year","fixed",{"perDose":46,"dosesPerDay":47},0.25,2,[49],{"source":32,"section":50},"2",{"min":52,"max":52},7,[54],{"text":55,"refs":58},{"fa":56,"en":57},"ویال را با دست گرم کنید تا سرگیجه نگیرد؛ گوش مبتلا رو به بالا.","Warm the container in the hand to avoid dizziness; affected ear upward.",[59],{"source":32,"section":50},[61,70],{"id":62,"severity":63,"text":64,"refs":67},"ci","block",{"fa":65,"en":66},"حساسیت به سیپروفلوکساسین.","Hypersensitivity to ciprofloxacin.",[68],{"source":32,"section":69},"4",{"id":71,"severity":63,"rule":72,"text":74,"refs":77},"under-1",{"maxAge":73},{"value":5,"unit":43},{"fa":75,"en":76},"زیر ۱ سال ثابت نشده.","Not established under 1 year.",[78],{"source":32,"section":79},"8.4",[],[],[],[],{"status":85,"reviewer":86,"date":86},"unverified",null,[88],{"regimen":36,"formulation":23,"input":89,"expect":92},{"ageYears":90,"weightKg":91},8,25,{"perDose":46,"mlPerDose":46},[94],"S02AA15",{"status":96,"forms":97,"refs":134},"registered",[98,102,106,110,114,118,122,126,130],{"code":99,"en":100,"fa":101},"09786","CIPROFLOXACIN 250MG\u002F5ML 100ML SUSP","سوسپانسیون سیپروفلوکساسین ۲۵۰ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۰۰ میلی‌لیتر",{"code":103,"en":104,"fa":105},"00295","CIPROFLOXACIN HCL 250MG TAB","قرص سیپروفلوکساسین هیدروکلراید ۲۵۰ میلی‌گرم",{"code":107,"en":108,"fa":109},"00296","CIPROFLOXACIN HCL 500MG TAB","قرص سیپروفلوکساسین هیدروکلراید ۵۰۰ میلی‌گرم",{"code":111,"en":112,"fa":113},"10757","CIPROFLOXACIN LACTATE 200MG\u002F100ML INF BOTTLE","محلول انفوزیون در بطری سیپروفلوکساسین لاکتات ۲۰۰ میلی‌گرم \u002F ۱۰۰ میلی‌لیتر",{"code":115,"en":116,"fa":117},"00294","CIPROFLOXACIN LACTATE 200MG\u002F100ML INF P-BAG","محلول انفوزیون سیپروفلوکساسین لاکتات ۲۰۰ میلی‌گرم \u002F ۱۰۰ میلی‌لیتر",{"code":119,"en":120,"fa":121},"02250","CIPROFLOXACIN LACTATE 200MG\u002F20ML INF","محلول انفوزیون سیپروفلوکساسین لاکتات ۲۰۰ میلی‌گرم \u002F ۲۰ میلی‌لیتر",{"code":123,"en":124,"fa":125},"52076","CIPROFLOXACIN INJECTION, SOLUTION INTRAVENOUS 10 mg\u002F1mL 40 mL","فرآورده تزریقی سیپروفلوکساسین ۱۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۴۰ میلی‌لیتر",{"code":127,"en":128,"fa":129},"52435","CIPROFLOXACIN (AS HYDROCHLORIDE) TABLET ORAL 750 mg","قرص سیپروفلوکساسین (معادل هیدروکلراید) ۷۵۰ میلی‌گرم",{"code":131,"en":132,"fa":133},"52801","CIPROFLOXACIN (AS LACTATE) INJECTION, SOLUTION INTRAVENOUS 2 mg\u002F1mL 200 mL","فرآورده تزریقی سیپروفلوکساسین (معادل لاکتات) ۲ میلی‌گرم \u002F ۱ میلی‌لیتر ۲۰۰ میلی‌لیتر",[135],{"source":136,"section":137,"url":138},"darooyab-generic","G-361\u002FCiprofloxacin","https:\u002F\u002Fwww.darooyab.ir\u002FG-361\u002FCiprofloxacin",[140,144,148,151],{"kind":141,"url":142,"label":143},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=217887","ANDA217887",{"kind":145,"url":146,"label":147},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=51dde3f2-adb1-4ed8-83c6-1f63723a2529","FDA Ciprofloxacin otic",{"kind":149,"url":150,"label":94},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=S02AA15",{"kind":152,"url":138,"label":153},"darooyab","Ciprofloxacin",{"pregnancy":155,"lactation":164,"pediatric":173,"geriatric":180},{"level":156,"text":157,"quote":160,"refs":161},"caution",{"fa":158,"en":159},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Pregnancy Category C.",[162],{"source":32,"section":163},"8.1",{"level":165,"text":166,"quote":169,"refs":170},"avoid",{"fa":167,"en":168},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[171],{"source":32,"section":172},"8.3",{"level":156,"text":174,"quote":177,"refs":178},{"fa":175,"en":176},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of ciprofloxacin otic solution, 0.2% in infants below one year of age have not been established.",[179],{"source":32,"section":79},{"level":181,"text":182,"quote":185,"refs":186},"ok",{"fa":183,"en":184},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety and effectiveness have been observed between elderly and younger patients.",[187],{"source":32,"section":188},"8.5",{"kind":190,"refs":191,"id":143},"ANDA",[192],{"source":32,"section":193},"SPL approval \u002F marketing category",1792440742983]