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Dose on total body weight regardless of obesity.",[88],{"source":35,"section":81},[24],{"id":91,"disease":69,"label":92,"population":95,"type":74,"unit":30,"dose":96,"refs":98,"notes":100,"allowedFormulations":105},"serious-4",{"fa":93,"en":94},"عفونت جدی — 8 تا 12 mg\u002Fkg\u002Fday در چهار نوبت","Serious infections — 8–12 mg\u002Fkg\u002Fday in 4 doses",{},{"perKgPerDay":76,"perKgPerDayMax":77,"dividedDoses":97},4,[99],{"source":35,"section":81},[101],{"text":102,"refs":103},{"fa":85,"en":86},[104],{"source":35,"section":81},[24],{"id":107,"disease":69,"label":108,"population":111,"type":74,"unit":30,"dose":112,"refs":115,"notes":117,"allowedFormulations":122},"severe-3",{"fa":109,"en":110},"عفونت شدید — 13 تا 16 mg\u002Fkg\u002Fday در سه نوبت","Severe infections — 13–16 mg\u002Fkg\u002Fday in 3 doses",{},{"perKgPerDay":113,"perKgPerDayMax":114,"dividedDoses":78},13,16,[116],{"source":35,"section":81},[118],{"text":119,"refs":120},{"fa":85,"en":86},[121],{"source":35,"section":81},[24],{"id":124,"disease":69,"label":125,"population":128,"type":74,"unit":30,"dose":129,"refs":130,"notes":132,"allowedFormulations":137},"severe-4",{"fa":126,"en":127},"عفونت شدید — 13 تا 16 mg\u002Fkg\u002Fday در چهار نوبت","Severe infections — 13–16 mg\u002Fkg\u002Fday in 4 doses",{},{"perKgPerDay":113,"perKgPerDayMax":114,"dividedDoses":97},[131],{"source":35,"section":81},[133],{"text":134,"refs":135},{"fa":85,"en":86},[136],{"source":35,"section":81},[24],{"id":139,"disease":69,"label":140,"population":143,"type":74,"unit":30,"dose":144,"refs":147,"notes":149,"allowedFormulations":154},"more-severe-3",{"fa":141,"en":142},"عفونت شدیدتر — 17 تا 25 mg\u002Fkg\u002Fday در سه نوبت","More severe infections — 17–25 mg\u002Fkg\u002Fday in 3 doses",{},{"perKgPerDay":145,"perKgPerDayMax":146,"dividedDoses":78},17,25,[148],{"source":35,"section":81},[150],{"text":151,"refs":152},{"fa":85,"en":86},[153],{"source":35,"section":81},[24],{"id":156,"disease":69,"label":157,"population":160,"type":74,"unit":30,"dose":161,"refs":162,"notes":164,"allowedFormulations":169},"more-severe-4",{"fa":158,"en":159},"عفونت شدیدتر — 17 تا 25 mg\u002Fkg\u002Fday در چهار نوبت","More severe infections — 17–25 mg\u002Fkg\u002Fday in 4 doses",{},{"perKgPerDay":145,"perKgPerDayMax":146,"dividedDoses":97},[163],{"source":35,"section":81},[165],{"text":166,"refs":167},{"fa":85,"en":86},[168],{"source":35,"section":81},[24],{"id":171,"disease":69,"label":172,"population":175,"type":179,"unit":30,"dose":180,"refs":181,"allowedFormulations":183},"cap-adult",{"fa":173,"en":174},"کپسول — بزرگسال: ۱۵۰ تا ۳۰۰ mg هر ۶ ساعت (شدیدتر ۳۰۰ تا ۴۵۰ mg)","Capsules — adult: 150–300 mg every 6 h (more severe 300–450 mg)",{"minAge":176},{"value":177,"unit":178},18,"year","fixed",{"perDose":42,"perDoseMax":52,"dosesPerDay":97},[182],{"source":47,"section":81},[38,49],{"id":185,"disease":69,"label":186,"population":189,"type":74,"unit":30,"dose":193,"refs":194,"allowedFormulations":196,"notes":197},"cap-child",{"fa":187,"en":188},"کپسول — کودکی که کپسول می‌بلعد: ۸ تا ۱۶ mg\u002Fkg\u002Fروز در ۳ تا ۴ دوز","Capsules — child able to swallow capsules: 8–16 mg\u002Fkg\u002Fday in 3–4 doses",{"minAge":190,"maxAge":192},{"value":191,"unit":178},6,{"value":177,"unit":178},{"perKgPerDay":76,"perKgPerDayMax":114,"dividedDoses":97},[195],{"source":47,"section":81},[38,49],[198],{"text":199,"refs":202},{"fa":200,"en":201},"عفونت شدیدتر ۱۶ تا ۲۰ mg\u002Fkg\u002Fروز. بر اساس وزن کل بدن حتی در چاقی.","More severe 16–20 mg\u002Fkg\u002Fday. Dose by total body weight, even in obesity.",[203],{"source":47,"section":81},{"id":205,"disease":69,"label":206,"population":209,"type":74,"unit":30,"dose":213,"refs":216,"allowedFormulations":218,"notes":219},"iv-child",{"fa":207,"en":208},"تزریقی — کودک ۱ ماه تا ۱۶ سال: ۲۰ تا ۴۰ mg\u002Fkg\u002Fروز در ۳ تا ۴ دوز","Injection — child 1 month–16 y: 20–40 mg\u002Fkg\u002Fday in 3–4 doses",{"minAge":210,"maxAge":212},{"value":5,"unit":211},"month",{"value":145,"unit":178},{"perKgPerDay":214,"perKgPerDayMax":215,"dividedDoses":97},20,40,[217],{"source":65,"section":81},[57],[220],{"text":221,"refs":224},{"fa":222,"en":223},"دوز بالاتر در عفونت شدیدتر. حاوی بنزیل الکل (خطر در نوزاد). تزریق عضلانی تک‌دوز بیش از ۶۰۰ mg توصیه نمی‌شود.","Higher doses for more severe infection. Contains benzyl alcohol (neonatal risk). Single IM injections >600 mg not recommended.",[225,226],{"source":65,"section":81},{"source":65,"section":227},"Warnings — Neonates",[229],{"id":230,"severity":231,"text":232,"refs":235},"hypersensitivity","block",{"fa":233,"en":234},"سابقه حساسیت به کلیندامایسین یا لینکومایسین.","History of hypersensitivity to clindamycin or lincomycin.",[236],{"source":35,"section":237},"Contraindications",[239],{"text":240,"refs":243},{"fa":241,"en":242},"هشدار جعبه‌ای: اسهال مرتبط با کلستریدیوئیدس دیفیسیل، از اسهال خفیف تا کولیت کشنده؛ فقط برای عفونت‌های جدی و وقتی داروی کم‌خطرتر مناسب نیست.","Boxed warning: Clostridioides difficile-associated diarrhea, mild to fatal colitis; reserve for serious infections where less toxic agents are inappropriate.",[244,246],{"source":35,"section":245},"WARNING (boxed)",{"source":35,"section":247},"Indications and Usage",[],[250],{"text":251,"refs":254},{"fa":252,"en":253},"در کودکان (تولد تا ۱۶ سال) پایش عملکرد ارگان‌ها مطلوب است.","In pediatric patients (birth to 16 years) monitor organ system function.",[255],{"source":35,"section":256},"Pediatric Use",[],{"status":259,"reviewer":260,"date":260},"unverified",null,[262,268,273,278,282,287,292,296,299],{"regimen":68,"formulation":24,"input":263,"expect":265},{"ageYears":78,"weightKg":264},15,{"perDose":215,"upperPerDose":266,"mlPerDose":267},60,2.67,{"regimen":91,"formulation":24,"input":269,"expect":270},{"ageYears":78,"weightKg":264},{"perDose":271,"upperPerDose":272},30,45,{"regimen":107,"formulation":24,"input":274,"expect":275},{"ageYears":78,"weightKg":264},{"perDose":276,"upperPerDose":277},65,80,{"regimen":124,"formulation":24,"input":279,"expect":280},{"ageYears":78,"weightKg":264},{"perDose":281,"upperPerDose":266},48.75,{"regimen":139,"formulation":24,"input":283,"expect":284},{"ageYears":78,"weightKg":264},{"perDose":285,"upperPerDose":286},85,125,{"regimen":156,"formulation":24,"input":288,"expect":289},{"ageYears":78,"weightKg":264},{"perDose":290,"upperPerDose":291},63.75,93.75,{"regimen":171,"formulation":38,"input":293,"expect":295},{"ageYears":215,"weightKg":294},70,{"perDose":42,"tabletsPerDoseRounded":5,"upperPerDose":52},{"regimen":185,"formulation":38,"input":297,"expect":298},{"ageYears":114,"weightKg":29},{"perDose":42,"tabletsPerDoseRounded":5,"upperPerDose":52},{"regimen":205,"formulation":57,"input":300,"expect":301},{"ageYears":31,"weightKg":214},{"perDose":302,"mlPerDose":303,"upperPerDose":304},100,0.67,200,[306],"J01FF01",{"status":308,"forms":309,"refs":370},"registered",[310,314,318,322,326,330,334,338,342,346,350,354,358,362,366],{"code":311,"en":312,"fa":313},"00311","CLINDAMYCIN 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میلی‌لیتر",[371],{"source":372,"section":373,"url":374},"darooyab-generic","G-366\u002FClindamycin","https:\u002F\u002Fwww.darooyab.ir\u002FG-366\u002FClindamycin",[376,380,384,387,390,393,396,399],{"kind":377,"url":378,"label":379},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=062644","ANDA062644",{"kind":381,"url":382,"label":383},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=1ef87b6c-9d32-44ac-8c55-8bf01424cc45","FDA Cleocin Pediatric",{"kind":381,"url":385,"label":386},"https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2367340c-d297-4a3f-8253-6d27a0ed39cb","FDA Clindamycin caps",{"kind":381,"url":388,"label":389},"https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=05a75685-0af5-407c-ac57-e380c882b49d","FDA Cleocin Phosphate",{"kind":391,"url":392,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682399.html",{"kind":391,"url":394,"label":395},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682382.html","Clindamycin Injection",{"kind":397,"url":398,"label":306},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J01FF01",{"kind":400,"url":374,"label":8},"darooyab",{"pregnancy":402,"lactation":411,"pediatric":419,"geriatric":426},{"level":403,"text":404,"quote":407,"refs":408},"caution",{"fa":405,"en":406},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal reproduction studies are not always predictive of the human response, this drug should be used during pregnancy only if clearly needed.",[409],{"source":35,"section":410},"Pregnancy: Teratogenic Effects",{"level":403,"text":412,"quote":415,"refs":416},{"fa":413,"en":414},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Limited published data based on breast milk sampling reports that clindamycin appears in human breast milk in the range of less than 0.5 to 3.8 mcg\u002FmL.",[417],{"source":35,"section":418},"Nursing Mothers",{"level":403,"text":420,"quote":423,"refs":424},{"fa":421,"en":422},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","When CLEOCIN PEDIATRIC is administered to the pediatric population (birth to 16 years), appropriate monitoring of organ system functions is desirable.",[425],{"source":35,"section":256},{"level":403,"text":427,"quote":430,"refs":431},{"fa":428,"en":429},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","These patients should be carefully monitored for the development of diarrhea.",[432],{"source":35,"section":433},"Geriatric Use",{"kind":435,"refs":436,"id":379},"ANDA",[437],{"source":35,"section":438},"SPL approval \u002F marketing category",1792191872289]