[{"data":1,"prerenderedAt":234},["ShallowReactive",2],{"drug-desloratadine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":24,"regimens":50,"contraindications":90,"warnings":102,"renal":116,"monitoring":117,"interactions":118,"review":119,"examples":121,"atc":137,"iran":139,"links":166,"populations":187,"usApproval":229},"desloratadine",1,{"fa":7,"en":8},"دسلوراتادین","Desloratadine","respiratory",{"fa":11,"en":12},"آنتی‌هیستامین نسل دوم","Second-generation antihistamine",[14,17],{"name":15,"market":16},"Clarinex","US",{"name":18,"market":19},"Neoclarityn","GB",[21,22,23],"دسلوراتادين","aerius","آئریوس",[25,38],{"id":26,"form":27,"route":28,"label":29,"concentration":30,"markets":33,"refs":34},"sol-0-5-1","solution","oral","0.5 mg \u002F mL oral solution",{"amount":31,"unit":32,"perVolumeMl":5},0.5,"mg",[19],[35],{"source":36,"section":37},"uk-smpc-neoclarityn","2",{"id":39,"form":40,"route":28,"label":41,"concentration":42,"markets":45,"refs":46},"tab-5","tablet","5 mg tablet",{"amount":43,"unit":32,"perUnit":40,"scored":44},5,false,[16],[47],{"source":48,"section":49},"fda-desloratadine-tab","3",[51],{"id":52,"disease":52,"label":53,"population":56,"type":59,"unit":32,"dose":60,"refs":78,"notes":83},"allergic-rhinitis",{"fa":54,"en":55},"رینیت آلرژیک و کهیر","Allergic rhinitis and urticaria",{"minAge":57},{"value":5,"unit":58},"year","ageBand",{"bands":61},[62,67,72],{"minAge":63,"maxAge":64,"perDose":66,"dosesPerDay":5},{"value":5,"unit":58},{"value":65,"unit":58},6,1.25,{"minAge":68,"maxAge":69,"perDose":71,"dosesPerDay":5},{"value":65,"unit":58},{"value":70,"unit":58},12,2.5,{"minAge":73,"maxAge":74,"perDose":43,"dosesPerDay":5,"refs":75},{"value":70,"unit":58},null,[76],{"source":48,"section":77},"2.1",[79,81],{"source":36,"section":80},"4.2",{"source":36,"section":82},"4.1",[84],{"text":85,"refs":88},{"fa":86,"en":87},"بیشتر رینیت‌های زیر ۲ سال عفونی است و برای رینیت عفونی داده‌ای نیست. بی‌خطری زیر ۱ سال ثابت نشده.","Most rhinitis under 2 years is infectious; no data for infectious rhinitis. Safety below 1 year not established.",[89],{"source":36,"section":80},[91],{"id":92,"severity":93,"text":94,"refs":97},"hypersensitivity","block",{"fa":95,"en":96},"حساسیت به دسلوراتادین یا لوراتادین.","Hypersensitivity to desloratadine or loratadine.",[98,100],{"source":36,"section":99},"4.3",{"source":48,"section":101},"4",[103,110],{"text":104,"refs":107},{"fa":105,"en":106},"احتیاط در سابقه تشنج، به‌ویژه کودکان کم‌سن.","Caution with personal or family history of seizures, mainly young children.",[108],{"source":36,"section":109},"4.4",{"text":111,"refs":114},{"fa":112,"en":113},"نارسایی شدید کلیه: با احتیاط.","Severe renal insufficiency: use with caution.",[115],{"source":36,"section":109},[],[],[],{"status":120,"reviewer":74,"date":74},"unverified",[122,127,132],{"regimen":52,"formulation":26,"input":123,"expect":126},{"ageYears":124,"weightKg":125},3,14,{"perDose":66,"mlPerDose":71},{"regimen":52,"formulation":26,"input":128,"expect":131},{"ageYears":129,"weightKg":130},8,25,{"perDose":71,"mlPerDose":43},{"regimen":52,"formulation":39,"input":133,"expect":136},{"ageYears":134,"weightKg":135},15,55,{"tabletsPerDoseRounded":5},[138],"R06AX27",{"status":140,"forms":141,"refs":161},"registered",[142,146,150,153,157],{"code":143,"en":144,"fa":145},"09633","DESLORATADINE 5MG TAB","قرص دسلوراتادین ۵ میلی‌گرم",{"code":147,"en":148,"fa":149},"09634","DESLORATADINE SYRUP","شربت دسلوراتادین",{"code":151,"en":152,"fa":145},"52136","DESLORATADINE TABLET ORAL 5 mg",{"code":154,"en":155,"fa":156},"52148","DESLORATADINE SYRUP ORAL 2.5 mg\u002F5 mL 120 mL","شربت دسلوراتادین ۲٫۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۲۰ میلی‌لیتر",{"code":158,"en":159,"fa":160},"52990","DESLORATADINE SYRUP ORAL 2.5 mg\u002F5 mL 60 mL","شربت دسلوراتادین ۲٫۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۶۰ میلی‌لیتر",[162],{"source":163,"section":164,"url":165},"darooyab-generic","G-788\u002FDesloratadine","https:\u002F\u002Fwww.darooyab.ir\u002FG-788\u002FDesloratadine",[167,171,175,178,181,183],{"kind":168,"url":169,"label":170},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=078352","ANDA078352",{"kind":172,"url":173,"label":174},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=69b9635b-c790-4316-a790-67b0f5512b72","FDA Desloratadine",{"kind":176,"url":177,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa602002.html",{"kind":179,"url":180,"label":138},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R06AX27",{"kind":182,"url":165,"label":8},"darooyab",{"kind":184,"url":185,"label":186},"emc","https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F6510\u002Fsmpc","UK SmPC Neoclarityn",{"pregnancy":188,"lactation":197,"pediatric":205,"geriatric":213,"reproductive":221},{"level":189,"text":190,"quote":193,"refs":194},"caution",{"fa":191,"en":192},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary The limited available data with desloratadine in pregnant women are not sufficient to inform a drug-associated risk for major birth defects and miscarriage.",[195],{"source":48,"section":196},"8.1",{"level":189,"text":198,"quote":201,"refs":202},{"fa":199,"en":200},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Desloratadine passes into breast milk.",[203],{"source":48,"section":204},"8.2",{"level":189,"text":206,"quote":209,"refs":210},{"fa":207,"en":208},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The recommended dose of desloratadine oral solution in the pediatric population is based on cross-study comparison of the plasma concentration of desloratadine in adults and pediatric subjects.",[211],{"source":48,"section":212},"8.4",{"level":189,"text":214,"quote":217,"refs":218},{"fa":215,"en":216},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.",[219],{"source":48,"section":220},"8.5",{"level":189,"text":222,"quote":225,"refs":226},{"fa":223,"en":224},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Infertility There are no data available on human infertility associated with desloratadine.",[227],{"source":48,"section":228},"8.3",{"kind":230,"refs":231,"id":170},"ANDA",[232],{"source":48,"section":233},"SPL approval \u002F marketing category",1792444716048]