[{"data":1,"prerenderedAt":194},["ShallowReactive",2],{"drug-hydroxocobalamin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":25,"regimens":39,"contraindications":77,"warnings":87,"renal":88,"monitoring":89,"interactions":90,"review":91,"examples":94,"atc":104,"iran":106,"links":162,"populations":177},"hydroxocobalamin",1,{"fa":7,"en":8},"هیدروکسوکوبالامین (ویتامین B12)","Hydroxocobalamin (vitamin B12)","blood",{"fa":11,"en":12},"ویتامین B12 تزریقی","Injectable vitamin B12",[14],{"name":15,"market":16},"Cobalin-H","GB",[18,19,20,21,22,23,24],"vitamin b12","b12","ب ۱۲","آمپول ب۱۲","ویتامین ب12","cobalamin","سیانوکوبالامین",[26],{"id":27,"form":28,"route":29,"label":30,"concentration":31,"markets":34,"refs":35},"inj-1000","injection","im","1,000 mcg\u002FmL (1 mg\u002FmL) injection",{"amount":32,"unit":33,"perVolumeMl":5},1000,"mcg",[16],[36],{"source":37,"section":38},"uk-smpc-hydroxocobalamin","2",[40,60],{"id":41,"disease":42,"label":43,"population":46,"type":47,"unit":33,"dose":48,"refs":50,"notes":53},"pa","b12-deficiency",{"fa":44,"en":45},"کم‌خونی پرنیشیوز بدون درگیری عصبی: ۱۰۰۰ mcg عضلانی یک روز در میان (۱ تا ۲ هفته)","Pernicious anaemia without neurological involvement: 1,000 mcg IM on alternate days (1–2 weeks)",{},"fixed",{"perDose":32,"dosesPerDay":5,"intervalHours":49},48,[51],{"source":37,"section":52},"4.2",[54],{"text":55,"refs":58},{"fa":56,"en":57},"شروع ۲۵۰ تا ۱۰۰۰ mcg یک روز در میان ۱ تا ۲ هفته، سپس ۲۵۰ mcg هفتگی تا طبیعی شدن شمارش؛ نگهدارنده ۱۰۰۰ mcg هر ۲ تا ۳ ماه. با درگیری عصبی: ۱۰۰۰ mcg یک روز در میان تا وقتی بهبود ادامه دارد. برای بزرگسال و کودک.","Initially 250–1,000 mcg on alternate days for 1–2 weeks, then 250 mcg weekly until counts normal; maintenance 1,000 mcg every 2–3 months. With neurological involvement: 1,000 mcg alternate days while improving. Adults and children.",[59],{"source":37,"section":52},{"id":61,"disease":42,"label":62,"population":65,"type":47,"unit":33,"dose":66,"refs":67,"durationDays":69,"notes":70},"maint",{"fa":63,"en":64},"نگهدارنده یا پیشگیری (گاسترکتومی، سوءجذب، گیاه‌خواری مطلق): ۱۰۰۰ mcg هر ۲ تا ۳ ماه","Maintenance or prophylaxis (gastrectomy, malabsorption, strict vegans): 1,000 mcg every 2–3 months",{},{"perDose":32,"dosesPerDay":5},[68],{"source":37,"section":52},{"min":5,"max":5},[71],{"text":72,"refs":75},{"fa":73,"en":74},"یک تزریق؛ هر ۲ تا ۳ ماه تکرار.","One injection; repeat every 2–3 months.",[76],{"source":37,"section":52},[78],{"id":79,"severity":80,"text":81,"refs":84},"ci","block",{"fa":82,"en":83},"حساسیت.","Hypersensitivity.",[85],{"source":37,"section":86},"4.3",[],[],[],[],{"status":92,"reviewer":93,"date":93},"unverified",null,[95,100],{"regimen":41,"formulation":27,"input":96,"expect":99},{"ageYears":97,"weightKg":98},60,70,{"perDose":32,"mlPerDose":5},{"regimen":61,"formulation":27,"input":101,"expect":103},{"ageYears":102,"weightKg":98},40,{"mlPerDose":5},[105],"B03BA03",{"status":107,"forms":108,"refs":157},"registered",[109,113,117,121,125,129,133,137,141,145,149,153],{"code":110,"en":111,"fa":112},"00646","HYDROXOCOBALAMIN 100MG\u002F1ML AMP","آمپول هیدروکسوکوبالامین ۱۰۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":114,"en":115,"fa":116},"10334","HYDROXOCOBALAMINE ACETATE 0.5MG\u002FML 2ML","هیدروکسوکوبالامین استات ۰٫۵ میلی‌گرم \u002F میلی‌لیتر ۲ میلی‌لیتر",{"code":118,"en":119,"fa":120},"08201","VITAMIN B12 1000MCG TAB","قرص ویتامین B ۱۲ ۱۰۰۰ میکروگرم",{"code":122,"en":123,"fa":124},"01294","VITAMIN B12 1000MCG\u002F1ML AMP","آمپول ویتامین B ۱۲ ۱۰۰۰ میکروگرم \u002F ۱ میلی‌لیتر",{"code":126,"en":127,"fa":128},"11462","VITAMIN B12 1000MCG\u002F4ML AMP","آمپول ویتامین B ۱۲ ۱۰۰۰ میکروگرم \u002F ۴ میلی‌لیتر",{"code":130,"en":131,"fa":132},"01746","VITAMIN B12 100MCG\u002F1ML AMP","آمپول ویتامین B ۱۲ ۱۰۰ میکروگرم \u002F ۱ میلی‌لیتر",{"code":134,"en":135,"fa":136},"11691","VITAMIN B12 1MG\u002F2ML ORAL AMP","آمپول ویتامین B ۱۲ ۱ میلی‌گرم \u002F ۲ میلی‌لیتر",{"code":138,"en":139,"fa":140},"02249","VITAMIN B12 50ML SOL","محلول ویتامین B ۱۲ ۵۰ میلی‌لیتر",{"code":142,"en":143,"fa":144},"18580","CYANOCOBOLAMIN 10ML EYE DROP","قطره چشمی سیانوکوبولامین ۱۰ میلی‌لیتر",{"code":146,"en":147,"fa":148},"23306","HYDROXOCOBALAMIN INJECTION, SOLUTION PARENTERAL 1000 ug\u002F1mL","محلول تزریقی هیدروکسوکوبالامین ۱۰۰۰ میکروگرم \u002F ۱ میلی‌لیتر",{"code":150,"en":151,"fa":152},"51899","HYDROXOCOBALAMIN INJECTION PARENTERAL 5 mg\u002F1mL 2 mL","فرآورده تزریقی هیدروکسوکوبالامین ۵ میلی‌گرم \u002F ۱ میلی‌لیتر ۲ میلی‌لیتر",{"code":154,"en":155,"fa":156},"52710","HYDROXOCOBALAMIN INJECTION, SOLUTION PARENTERAL 1500 ug\u002F1mL 1 mL","محلول تزریقی هیدروکسوکوبالامین ۱۵۰۰ میکروگرم \u002F ۱ میلی‌لیتر ۱ میلی‌لیتر",[158],{"source":159,"section":160,"url":161},"darooyab-generic","G-2950\u002FVitamin-B12","https:\u002F\u002Fwww.darooyab.ir\u002FG-2950\u002FVitamin-B12",[163,167,170,173],{"kind":164,"url":165,"label":166},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa605007.html","Cyanocobalamin Injection",{"kind":168,"url":169,"label":105},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B03BA03",{"kind":171,"url":161,"label":172},"darooyab","Vitamin-B12",{"kind":174,"url":175,"label":176},"emc","https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F100455\u002Fsmpc","UK SmPC Hydroxocobalamin",{"pregnancy":178,"lactation":187},{"level":179,"text":180,"quote":183,"refs":184},"caution",{"fa":181,"en":182},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Hydroxocobalamin injection should not be used for the treatment of megaloblastic anaemia of pregnancy.",[185],{"source":37,"section":186},"4.6",{"level":179,"text":188,"quote":191,"refs":192},{"fa":189,"en":190},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Hydroxocobalamin is secreted into breast milk but is unlikely to harm the infant.",[193],{"source":37,"section":186},1792440721719]