[{"data":1,"prerenderedAt":156},["ShallowReactive",2],{"drug-indapamide":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":61,"warnings":80,"renal":81,"monitoring":82,"interactions":83,"review":84,"examples":87,"atc":93,"iran":95,"links":111,"populations":124},"indapamide",1,{"fa":7,"en":8},"اینداپامید","Indapamide","cardiovascular",{"fa":11,"en":12},"دیورتیک شبه‌تیازید","Thiazide-like diuretic",[14],{"name":15,"market":16},"Natrilix","GB",[18,19,7],"natrilix","ناتریلیکس",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-2-5","tablet","oral","2.5 mg coated tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},2.5,"mg",false,[16],[32],{"source":33,"section":34},"uk-smpc-indapamide","2",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":48,"limits":51,"notes":54},"htn","hypertension",{"fa":40,"en":41},"فشار خون — ۲٫۵ mg صبح","Hypertension — 2.5 mg in the morning",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":27,"dosesPerDay":5},[49],{"source":33,"section":50},"4.2",{"maxPerDay":27,"refs":52},[53],{"source":33,"section":50},[55],{"text":56,"refs":59},{"fa":57,"en":58},"دوز بالاتر توصیه نمی‌شود (اثر ضدفشار بیشتری ندارد). اثر کامل ممکن است چند ماه طول بکشد.","Higher doses not recommended (no added antihypertensive effect). Full effect may take months.",[60],{"source":33,"section":50},[62,71],{"id":63,"severity":64,"text":65,"refs":68},"ci","block",{"fa":66,"en":67},"حساسیت به اینداپامید یا سولفونامیدها؛ نارسایی شدید کلیه یا کبد؛ هیپوکالمی؛ پورفیری؛ آدیسون؛ هیپوناترمی یا هیپرکلسمی مقاوم.","Hypersensitivity to indapamide or sulfonamides; severe renal or hepatic failure; hypokalaemia; porphyria; Addison's disease; refractory hyponatraemia or hypercalcaemia.",[69],{"source":33,"section":70},"4.3",{"id":72,"severity":64,"rule":73,"text":75,"refs":78},"child",{"maxAge":74},{"value":44,"unit":45},{"fa":76,"en":77},"دوز کودکان در این SmPC نیامده.","No pediatric dose in this SmPC.",[79],{"source":33,"section":50},[],[],[],[],{"status":85,"reviewer":86,"date":86},"unverified",null,[88],{"regimen":37,"formulation":22,"input":89,"expect":92},{"ageYears":90,"weightKg":91},55,80,{"perDose":27},[94],"C03BA11",{"status":96,"forms":97,"refs":106},"registered",[98,102],{"code":99,"en":100,"fa":101},"05637","INDAPAMIDE 1.5MG TAB","قرص اینداپامید ۱٫۵ میلی‌گرم",{"code":103,"en":104,"fa":105},"52031","INDAPAMIDE TABLET ORAL 2.5 mg","قرص اینداپامید ۲٫۵ میلی‌گرم",[107],{"source":108,"section":109,"url":110},"darooyab-generic","G-1713\u002FIndapamide","https:\u002F\u002Fwww.darooyab.ir\u002FG-1713\u002FIndapamide",[112,115,118,120],{"kind":113,"url":114,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa684062.html",{"kind":116,"url":117,"label":94},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C03BA11",{"kind":119,"url":110,"label":8},"darooyab",{"kind":121,"url":122,"label":123},"emc","https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F14345\u002Fsmpc","UK SmPC Indapamide",{"pregnancy":125,"lactation":134,"pediatric":141,"geriatric":149},{"level":126,"text":127,"quote":130,"refs":131},"caution",{"fa":128,"en":129},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","There are no or limited amount of data (less than 300 pregnancy outcomes) from the use of indapamide in pregnant women.",[132],{"source":33,"section":133},"4.6",{"level":126,"text":135,"quote":138,"refs":139},{"fa":136,"en":137},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Indapamide is excreted in human milk in small amounts.Hypersensitivity to sulfonamide-derived medicines and hypokalaemia might occur.",[140],{"source":33,"section":133},{"level":142,"text":143,"quote":146,"refs":147},"not-established",{"fa":144,"en":145},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Paediatric population: Indapamide is not recommended for use in children and adolescents due to a lack of data on safety and efficacy.",[148],{"source":33,"section":50},{"level":126,"text":150,"quote":153,"refs":154},{"fa":151,"en":152},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Elderly (see section 4.4): In the elderly, the plasma creatinine must be adjusted in relation to age, weight and gender.",[155],{"source":33,"section":50},1792191868565]