[{"data":1,"prerenderedAt":227},["ShallowReactive",2],{"drug-irbesartan":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":51,"contraindications":106,"warnings":125,"renal":126,"monitoring":127,"interactions":128,"review":129,"examples":132,"atc":143,"iran":145,"links":172,"populations":189,"usApproval":222},"irbesartan",1,{"fa":7,"en":8},"ایربسارتان","Irbesartan","cardiovascular",{"fa":11,"en":12},"ARB","Angiotensin receptor blocker",[14],{"name":15,"market":16},"Avapro","US",[18,19,7,11],"avapro","آواپرو",[21,35,43],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-75","tablet","oral","75 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},75,"mg",false,[16],[32],{"source":33,"section":34},"fda-irbesartan","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-150","150 mg tablet",{"amount":39,"unit":28,"perUnit":23,"scored":29},150,[16],[42],{"source":33,"section":34},{"id":44,"form":23,"route":24,"label":45,"concentration":46,"markets":48,"refs":49},"tab-300","300 mg tablet",{"amount":47,"unit":28,"perUnit":23,"scored":29},300,[16],[50],{"source":33,"section":34},[52,79,91],{"id":53,"disease":54,"label":55,"population":58,"type":62,"unit":28,"dose":63,"refs":64,"limits":67,"notes":70},"htn","hypertension",{"fa":56,"en":57},"فشار خون — ۱۵۰ mg یک بار در روز","Hypertension — 150 mg once daily",{"minAge":59},{"value":60,"unit":61},18,"year","fixed",{"perDose":39,"dosesPerDay":5},[65],{"source":33,"section":66},"2.2",{"maxPerDay":47,"refs":68},[69],{"source":33,"section":66},[71],{"text":72,"refs":75},{"fa":73,"en":74},"حداکثر ۳۰۰ mg. کم‌آبی یا دیالیز: شروع ۷۵ mg.","Max 300 mg. 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Dangerous in pregnancy.","WARNING: FETAL TOXICITY See full prescribing information for complete boxed warning. • When pregnancy is detected, discontinue irbesartan tablets as soon as possible.",[197],{"source":33,"section":124},{"level":199,"text":200,"quote":203,"refs":204},"caution",{"fa":201,"en":202},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","There are no available data on the presence of irbesartan in human milk, effects on milk production, or the breastfed infant.",[205],{"source":33,"section":206},"8.2",{"level":199,"text":208,"quote":211,"refs":212},{"fa":209,"en":210},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Irbesartan, in a study at a dose of up to 4.5 mg\u002Fkg\u002Fday, once daily, did not appear to lower blood pressure effectively in pediatric patients ages 6 to 16 years.",[213],{"source":33,"section":105},{"level":199,"text":215,"quote":218,"refs":219},{"fa":216,"en":217},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of 4925 subjects receiving irbesartan tablets in controlled clinical studies of hypertension, 911 (18.5%) were 65 years and over, while 150 (3.0%) were 75 years and over.",[220],{"source":33,"section":221},"8.5",{"kind":223,"refs":224,"id":176},"ANDA",[225],{"source":33,"section":226},"SPL approval \u002F marketing category",1792444702321]