[{"data":1,"prerenderedAt":200},["ShallowReactive",2],{"drug-lactulose":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":14,"formulations":16,"regimens":32,"contraindications":75,"warnings":85,"renal":86,"monitoring":87,"interactions":88,"review":89,"examples":92,"atc":98,"iran":100,"links":152,"populations":169,"usApproval":195},"lactulose",1,{"fa":7,"en":8},"لاکتولوز","Lactulose","alimentary-metabolism",{"fa":11,"en":12},"ملین اسموتیک","Osmotic laxative",[],[15],"لاکتولوز شربت",[17],{"id":18,"form":19,"route":20,"label":21,"concentration":22,"markets":26,"refs":28},"sol-10g-15","solution","oral","10 g \u002F 15 mL",{"amount":23,"unit":24,"perVolumeMl":25},10,"g",15,[27],"US",[29],{"source":30,"section":31},"fda-lactulose","Dosage and Administration",[33,52],{"id":34,"disease":35,"label":36,"population":39,"type":43,"unit":44,"dose":45,"refs":49},"pediatric","constipation",{"fa":37,"en":38},"کودکان","Pediatric patients",{"maxAge":40},{"value":41,"unit":42},18,"year","notCalculated","mg",{"reason":46},{"fa":47,"en":48},"بی‌خطری و اثربخشی در کودکان در این برچسب ثابت نشده است؛ دوز محاسبه نمی‌شود.","Safety and effectiveness in pediatric patients have not been established in this label; no dose is calculated.",[50],{"source":30,"section":51},"Pediatric Use",{"id":53,"disease":35,"label":54,"population":57,"type":59,"unit":60,"dose":61,"refs":62,"limits":64,"notes":68},"adult",{"fa":55,"en":56},"بزرگسالان — ۱۵ mL روزانه","Adults — 15 mL daily",{"minAge":58},{"value":41,"unit":42},"fixed","mL",{"perDose":25,"dosesPerDay":5},[63],{"source":30,"section":31},{"maxPerDay":65,"refs":66},60,[67],{"source":30,"section":31},[69],{"text":70,"refs":73},{"fa":71,"en":72},"دوز معمول ۱۵ تا ۳۰ mL روزانه؛ در صورت نیاز تا ۶۰ mL روزانه. ۲۴ تا ۴۸ ساعت ممکن است تا اجابت مزاج طول بکشد.","Usual dose 15–30 mL daily; may increase to 60 mL daily if necessary. 24–48 h may be required to produce a bowel movement.",[74],{"source":30,"section":31},[76],{"id":77,"severity":78,"text":79,"refs":82},"low-galactose-diet","block",{"fa":80,"en":81},"بیمارانی که رژیم کم‌گالاکتوز نیاز دارند.","Patients who require a low-galactose diet.",[83],{"source":30,"section":84},"Contraindications",[],[],[],[],{"status":90,"reviewer":91,"date":91},"unverified",null,[93],{"regimen":53,"formulation":18,"input":94,"expect":97},{"ageYears":95,"weightKg":96},40,70,{"perDose":25,"mlPerDose":25},[99],"A06AD11",{"status":101,"forms":102,"refs":147},"registered",[103,107,111,115,119,123,127,131,135,139,143],{"code":104,"en":105,"fa":106},"01565","LACTULOSE 10 G SACHET","ساشه لاکتولوز ۱۰ گرم",{"code":108,"en":109,"fa":110},"19734","LACTULOSE 10G\u002F15ML 120ML SYRUP","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۱۲۰ میلی‌لیتر",{"code":112,"en":113,"fa":114},"00731","LACTULOSE 10G\u002F15ML 240ML SYRUP","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۲۴۰ میلی‌لیتر",{"code":116,"en":117,"fa":118},"11540","LACTULOSE 10G\u002F15ML SUSP","سوسپانسیون لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر",{"code":120,"en":121,"fa":122},"11474","LACTULOSE 300ML SYRUP","شربت لاکتولوز ۳۰۰ میلی‌لیتر",{"code":124,"en":125,"fa":126},"52072","LACTULOSE SYRUP ORAL 10 g\u002F15mL 100 mL","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۱۰۰ میلی‌لیتر",{"code":128,"en":129,"fa":130},"52075","LACTULOSE SYRUP ORAL 10 g\u002F15mL 250 mL","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۲۵۰ میلی‌لیتر",{"code":132,"en":133,"fa":134},"52081","LACTULOSE SYRUP ORAL 10 g\u002F15mL 200 mL","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۲۰۰ میلی‌لیتر",{"code":136,"en":137,"fa":138},"51935","LACTULOSE SYRUP ORAL 10 g\u002F15mL 15 mL","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۱۵ میلی‌لیتر",{"code":140,"en":141,"fa":142},"52217","LACTULOSE SYRUP ORAL 10 g\u002F15mL 300 mL","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۳۰۰ میلی‌لیتر",{"code":144,"en":145,"fa":146},"52150","LACTULOSE SYRUP ORAL 10 g\u002F15mL 500 mL","شربت لاکتولوز ۱۰ گرم \u002F ۱۵ میلی‌لیتر ۵۰۰ میلی‌لیتر",[148],{"source":149,"section":150,"url":151},"darooyab-generic","G-2598\u002FLactulose","https:\u002F\u002Fwww.darooyab.ir\u002FG-2598\u002FLactulose",[153,157,161,164,167],{"kind":154,"url":155,"label":156},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=090503","ANDA090503",{"kind":158,"url":159,"label":160},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=8b79d0d6-b9e3-436e-bab7-01451b6f45cd","FDA Lactulose",{"kind":162,"url":163,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682338.html",{"kind":165,"url":166,"label":99},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A06AD11",{"kind":168,"url":151,"label":8},"darooyab",{"pregnancy":170,"lactation":179,"pediatric":187},{"level":171,"text":172,"quote":175,"refs":176},"caution",{"fa":173,"en":174},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Teratogenic Effects Pregnancy category B.",[177],{"source":30,"section":178},"Pregnancy",{"level":171,"text":180,"quote":183,"refs":184},{"fa":181,"en":182},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when lactulose solution is administered to a nursing woman.",[185],{"source":30,"section":186},"Nursing Mothers",{"level":188,"text":189,"quote":192,"refs":193},"not-established",{"fa":190,"en":191},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[194],{"source":30,"section":51},{"kind":196,"refs":197,"id":156},"ANDA",[198],{"source":30,"section":199},"SPL approval \u002F marketing category",1792191865422]