[{"data":1,"prerenderedAt":224},["ShallowReactive",2],{"drug-mebendazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":19,"formulations":22,"regimens":38,"contraindications":96,"warnings":116,"renal":124,"monitoring":125,"interactions":126,"review":127,"examples":130,"atc":155,"iran":157,"links":169,"populations":186,"usApproval":219},"mebendazole",1,{"fa":7,"en":8},"مبندازول","Mebendazole","antiparasitic",{"fa":11,"en":12},"ضدکرم بنزیمیدازول","Benzimidazole anthelmintic",[14,17],{"name":15,"market":16},"Emverm","US",{"name":18,"market":16},"Vermox",[20,21,7],"vermox","ورموکس",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":33,"refs":34},"chew-100","chewable-tablet","oral","100 mg chewable tablet",{"amount":29,"unit":30,"perUnit":31,"scored":32},100,"mg","tablet",false,[16],[35],{"source":36,"section":37},"fda-emverm","3",[39,62,74,85],{"id":40,"disease":40,"label":41,"population":44,"type":48,"unit":30,"dose":49,"refs":50,"durationDays":53,"notes":54},"pinworm",{"fa":42,"en":43},"کرمک — ۱۰۰ mg تک‌دوز","Pinworm — 100 mg once",{"minAge":45},{"value":46,"unit":47},2,"year","fixed",{"perDose":29,"dosesPerDay":5},[51],{"source":36,"section":52},"2, Table 1",{"min":5,"max":5},[55],{"text":56,"refs":59},{"fa":57,"en":58},"اگر ۳ هفته بعد بهبود نیافت، دوره دوم داده شود. قرص را می‌توان جوید، بلعید یا خرد کرد.","If not cured 3 weeks after treatment, a second course is advised. May be chewed, swallowed or crushed.",[60],{"source":36,"section":61},"2",{"id":63,"disease":63,"label":64,"population":67,"type":48,"unit":30,"dose":69,"refs":70,"durationDays":72},"whipworm",{"fa":65,"en":66},"کرم شلاقی — ۱۰۰ mg صبح و شب، ۳ روز","Whipworm — 100 mg morning and evening for 3 days",{"minAge":68},{"value":46,"unit":47},{"perDose":29,"dosesPerDay":46},[71],{"source":36,"section":52},{"min":73,"max":73},3,{"id":75,"disease":75,"label":76,"population":79,"type":48,"unit":30,"dose":81,"refs":82,"durationDays":84},"ascariasis",{"fa":77,"en":78},"آسکاریس — ۱۰۰ mg صبح و شب، ۳ روز","Roundworm — 100 mg morning and evening for 3 days",{"minAge":80},{"value":46,"unit":47},{"perDose":29,"dosesPerDay":46},[83],{"source":36,"section":52},{"min":73,"max":73},{"id":86,"disease":86,"label":87,"population":90,"type":48,"unit":30,"dose":92,"refs":93,"durationDays":95},"hookworm",{"fa":88,"en":89},"کرم قلابدار — ۱۰۰ mg صبح و شب، ۳ روز","Hookworm — 100 mg morning and evening for 3 days",{"minAge":91},{"value":46,"unit":47},{"perDose":29,"dosesPerDay":46},[94],{"source":36,"section":52},{"min":73,"max":73},[97,106],{"id":98,"severity":99,"text":100,"refs":103},"hypersensitivity","block",{"fa":101,"en":102},"حساسیت به مبندازول.","Hypersensitivity to mebendazole.",[104],{"source":36,"section":105},"4",{"id":107,"severity":99,"rule":108,"text":110,"refs":113},"under-2",{"maxAge":109},{"value":46,"unit":47},{"fa":111,"en":112},"بی‌خطری زیر ۲ سال ثابت نشده؛ تشنج در زیر ۱ سال گزارش شده است.","Not established under 2 years; convulsions reported under 1 year.",[114],{"source":36,"section":115},"8.4",[117],{"text":118,"refs":121},{"fa":119,"en":120},"همراه مترونیدازول مصرف نشود (واکنش‌های جدی پوستی).","Avoid with metronidazole (serious skin reactions).",[122],{"source":36,"section":123},"17",[],[],[],{"status":128,"reviewer":129,"date":129},"unverified",null,[131,136,142,145,150],{"regimen":40,"formulation":24,"input":132,"expect":135},{"ageYears":133,"weightKg":134},4,16,{"tabletsPerDoseRounded":5},{"regimen":63,"formulation":24,"input":137,"expect":140},{"ageYears":138,"weightKg":139},6,20,{"perDay":141},200,{"regimen":75,"formulation":24,"input":143,"expect":144},{"ageYears":138,"weightKg":139},{"tabletsPerDoseRounded":5},{"regimen":86,"formulation":24,"input":146,"expect":149},{"ageYears":147,"weightKg":148},30,70,{"perDose":29},{"regimen":40,"formulation":24,"input":151,"expect":153},{"ageYears":5,"weightKg":152},10,{"status":154},"blocked",[156],"P02CA01",{"status":158,"forms":159,"refs":164},"registered",[160],{"code":161,"en":162,"fa":163},"00786","MEBENDAZOLE 100MG CHEWABLE TAB","قرص جویدنی مبندازول ۱۰۰ میلی‌گرم",[165],{"source":166,"section":167,"url":168},"darooyab-generic","G-242\u002FMebendazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-242\u002FMebendazole",[170,174,178,181,184],{"kind":171,"url":172,"label":173},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=073580","ANDA073580",{"kind":175,"url":176,"label":177},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=a8c46363-f739-4f6e-bca8-1ce5e8d3f78d","FDA Emverm",{"kind":179,"url":180,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682315.html",{"kind":182,"url":183,"label":156},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=P02CA01",{"kind":185,"url":168,"label":8},"darooyab",{"pregnancy":187,"lactation":196,"pediatric":204,"geriatric":211},{"level":188,"text":189,"quote":192,"refs":193},"caution",{"fa":190,"en":191},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary The available published literature on mebendazole use in pregnant women has not reported a clear association between mebendazole and a potential risk of major birth defects or miscarriages [see Data].",[194],{"source":36,"section":195},"8.1",{"level":188,"text":197,"quote":200,"refs":201},{"fa":198,"en":199},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Limited data from case reports demonstrate that a small amount of mebendazole is present in human milk following oral administration.",[202],{"source":36,"section":203},"8.2",{"level":188,"text":205,"quote":208,"refs":209},{"fa":206,"en":207},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of EMVERM ® 100 mg chewable tablets has not been established in pediatric patients less than two years of age.",[210],{"source":36,"section":115},{"level":188,"text":212,"quote":215,"refs":216},{"fa":213,"en":214},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of mebendazole did not include sufficient numbers of subjects aged 65 and older to determine whether they respond differently from younger subjects.",[217],{"source":36,"section":218},"8.5",{"kind":220,"refs":221,"id":173},"ANDA",[222],{"source":36,"section":223},"SPL approval \u002F marketing category",1792191881490]