[{"data":1,"prerenderedAt":232},["ShallowReactive",2],{"drug-nifedipine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":25,"regimens":48,"contraindications":110,"warnings":120,"renal":121,"monitoring":122,"interactions":123,"review":124,"examples":127,"atc":136,"iran":138,"links":178,"populations":193,"usApproval":227},"nifedipine",1,{"fa":7,"en":8},"نیفدیپین آهسته‌رهش","Nifedipine extended-release","cardiovascular",{"fa":11,"en":12},"مسدودکننده کانال کلسیم","Calcium-channel blocker",[14,17],{"name":15,"market":16},"Procardia XL","US",{"name":18,"market":19},"Adalat","GB",[21,22,23,24],"procardia","adalat","آدالات","نیفدیپین",[26,40],{"id":27,"form":28,"route":29,"label":30,"concentration":31,"markets":35,"refs":36},"tab-30","tablet","oral","30 mg tablet",{"amount":32,"unit":33,"perUnit":28,"scored":34},30,"mg",false,[16],[37],{"source":38,"section":39},"fda-nifedipine","How Supplied",{"id":41,"form":28,"route":29,"label":42,"concentration":43,"markets":45,"refs":46},"tab-60","60 mg tablet",{"amount":44,"unit":33,"perUnit":28,"scored":34},60,[16],[47],{"source":38,"section":39},[49,75,95],{"id":50,"disease":51,"label":52,"population":55,"type":59,"unit":33,"dose":60,"refs":61,"limits":64,"notes":68},"htn","hypertension",{"fa":53,"en":54},"فشار خون — آهسته‌رهش ۳۰ یا ۶۰ mg یک بار در روز","Hypertension — extended-release 30 or 60 mg once daily",{"minAge":56},{"value":57,"unit":58},18,"year","fixed",{"perDose":32,"perDoseMax":44,"dosesPerDay":5},[62],{"source":38,"section":63},"Dosage and Administration",{"maxPerDay":65,"refs":66},120,[67],{"source":38,"section":63},[69],{"text":70,"refs":73},{"fa":71,"en":72},"کامل بلعیده شود. بالای ۱۲۰ mg توصیه نمی‌شود.","Swallow whole. Titration above 120 mg not recommended.",[74],{"source":38,"section":63},{"id":76,"disease":76,"label":77,"population":80,"type":59,"unit":33,"dose":82,"refs":83,"limits":85,"notes":88},"angina",{"fa":78,"en":79},"آنژین — آهسته‌رهش ۳۰ یا ۶۰ mg یک بار در روز","Angina — extended-release 30 or 60 mg once daily",{"minAge":81},{"value":57,"unit":58},{"perDose":32,"perDoseMax":44,"dosesPerDay":5},[84],{"source":38,"section":63},{"maxPerDay":65,"refs":86},[87],{"source":38,"section":63},[89],{"text":90,"refs":93},{"fa":91,"en":92},"تجربه بالای ۹۰ mg در آنژین محدود است.","Experience above 90 mg in angina is limited.",[94],{"source":38,"section":63},{"id":96,"disease":51,"label":97,"population":100,"type":102,"unit":33,"dose":103,"refs":107},"peds",{"fa":98,"en":99},"زیر ۱۸ سال","Under 18 years",{"maxAge":101},{"value":57,"unit":58},"notCalculated",{"reason":104},{"fa":105,"en":106},"بی‌خطری و اثربخشی در کودکان ثابت نشده است.","Safety and effectiveness in children not established.",[108],{"source":38,"section":109},"Pediatric Use",[111],{"id":112,"severity":113,"text":114,"refs":117},"ci","block",{"fa":115,"en":116},"حساسیت به نیفدیپین.","Hypersensitivity to nifedipine.",[118],{"source":38,"section":119},"Contraindications",[],[],[],[],{"status":125,"reviewer":126,"date":126},"unverified",null,[128,133],{"regimen":50,"formulation":27,"input":129,"expect":132},{"ageYears":130,"weightKg":131},55,80,{"perDose":32,"upperPerDose":44},{"regimen":76,"formulation":27,"input":134,"expect":135},{"ageYears":44,"weightKg":131},{"perDose":32},[137],"C08CA05",{"status":139,"forms":140,"refs":173},"registered",[141,145,149,153,157,161,165,169],{"code":142,"en":143,"fa":144},"00902","NIFEDIPINE 10MG PEARL","کپسول نرم نیفدیپین ۱۰ میلی‌گرم",{"code":146,"en":147,"fa":148},"00903","NIFEDIPINE 10MG TAB","قرص نیفدیپین ۱۰ میلی‌گرم",{"code":150,"en":151,"fa":152},"07772","NIFEDIPINE 20MG SR CAP","کپسول آهسته‌رهش نیفدیپین ۲۰ میلی‌گرم",{"code":154,"en":155,"fa":156},"19211","NIFEDIPINE 20MG SR TAB","قرص آهسته‌رهش نیفدیپین ۲۰ میلی‌گرم",{"code":158,"en":159,"fa":160},"01979","NIFEDIPINE 20MG TAB","قرص نیفدیپین ۲۰ میلی‌گرم",{"code":162,"en":163,"fa":164},"01612","NIFEDIPINE 240MG\u002F10ML ORAL DROP","قطره خوراکی نیفدیپین ۲۴۰ میلی‌گرم \u002F ۱۰ میلی‌لیتر",{"code":166,"en":167,"fa":168},"01994","NIFEDIPINE 30MG SR CAP","کپسول آهسته‌رهش نیفدیپین ۳۰ میلی‌گرم",{"code":170,"en":171,"fa":172},"02167","NIFEDIPINE 30MG SR TAB","قرص آهسته‌رهش نیفدیپین ۳۰ میلی‌گرم",[174],{"source":175,"section":176,"url":177},"darooyab-generic","G-1795\u002FNifedipine","https:\u002F\u002Fwww.darooyab.ir\u002FG-1795\u002FNifedipine",[179,183,187,190],{"kind":180,"url":181,"label":182},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=019684","NDA019684",{"kind":184,"url":185,"label":186},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=8ebcb33c-f43b-4b36-9f94-9774b2a59e06","FDA Procardia XL",{"kind":188,"url":189,"label":137},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C08CA05",{"kind":191,"url":177,"label":192},"darooyab","Nifedipine",{"pregnancy":194,"lactation":203,"pediatric":211,"geriatric":219},{"level":195,"text":196,"quote":199,"refs":200},"caution",{"fa":197,"en":198},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","PROCARDIA XL Extended Release Tablets should be used during pregnancy only if the potential benefit justifies the potential risk.",[201],{"source":38,"section":202},"Pregnancy",{"level":195,"text":204,"quote":207,"refs":208},{"fa":205,"en":206},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Nifedipine is transferred through breast milk.",[209],{"source":38,"section":210},"Lactation",{"level":212,"text":213,"quote":216,"refs":217},"not-established",{"fa":214,"en":215},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[218],{"source":38,"section":109},{"level":195,"text":220,"quote":223,"refs":224},{"fa":221,"en":222},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Age appears to have a significant effect on the pharmacokinetics of nifedipine.",[225],{"source":38,"section":226},"Geriatric Use",{"kind":228,"refs":229,"id":182},"NDA",[230],{"source":38,"section":231},"SPL approval \u002F marketing category",1792440724793]