[{"data":1,"prerenderedAt":254},["ShallowReactive",2],{"drug-omeprazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":37,"contraindications":124,"warnings":134,"renal":135,"monitoring":136,"interactions":137,"review":138,"examples":140,"atc":164,"iran":166,"links":198,"populations":215,"usApproval":249},"omeprazole",1,{"fa":7,"en":8},"امپرازول","Omeprazole","alimentary-metabolism",{"fa":11,"en":12},"مهارکننده پمپ پروتون","Proton pump inhibitor",[14],{"name":15,"market":16},"Prilosec","US",[18,7,19,20,21],"omeprazol","لوسک","losec","PPI",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":32,"refs":33},"cap-20","capsule","oral","20 mg delayed-release capsule",{"amount":29,"unit":30,"perUnit":25,"scored":31},20,"mg",false,[16],[34],{"source":35,"section":36},"fda-omeprazole-cap","3",[38,75,99,112],{"id":39,"disease":40,"label":41,"population":44,"type":51,"unit":30,"dose":52,"refs":59,"durationDays":64,"notes":66},"gerd-child","gerd",{"fa":42,"en":43},"ریفلاکس علامتی — ۲ تا ۱۶ سال","Symptomatic GERD — 2 to 16 years",{"minAge":45,"maxAge":48,"minWeightKg":50},{"value":46,"unit":47},2,"year",{"value":49,"unit":47},17,10,"weightBand",{"weightBands":53},[54,57],{"minWeightKg":55,"maxWeightKg":56,"perDose":50,"dosesPerDay":5},9.99,19.99,{"minWeightKg":56,"maxWeightKg":58,"perDose":29,"dosesPerDay":5},null,[60,62],{"source":35,"section":61},"2.2, Table 2",{"source":35,"section":63},"8.4",{"min":5,"max":65},28,[67],{"text":68,"refs":71},{"fa":69,"en":70},"۱۰ تا کمتر از ۲۰ kg: ۱۰ mg؛ ۲۰ kg به بالا: ۲۰ mg؛ یک‌بار در روز قبل از غذا. کپسول ۲۰ mg برای دوز ۱۰ mg مناسب نیست.","10 to \u003C20 kg: 10 mg; ≥20 kg: 20 mg; once daily before meals. A 20 mg capsule cannot give 10 mg.",[72,73],{"source":35,"section":61},{"source":35,"section":74},"2.3",{"id":76,"disease":77,"label":78,"population":81,"type":51,"unit":30,"dose":84,"refs":88,"durationDays":91,"notes":93},"ee-child","erosive-esophagitis",{"fa":79,"en":80},"ازوفاژیت فرسایشی — ۲ تا ۱۶ سال","Erosive esophagitis — 2 to 16 years",{"minAge":82,"maxAge":83,"minWeightKg":50},{"value":46,"unit":47},{"value":49,"unit":47},{"weightBands":85},[86,87],{"minWeightKg":55,"maxWeightKg":56,"perDose":50,"dosesPerDay":5},{"minWeightKg":56,"maxWeightKg":58,"perDose":29,"dosesPerDay":5},[89,90],{"source":35,"section":61},{"source":35,"section":63},{"min":65,"max":92},56,[94],{"text":95,"refs":96},{"fa":69,"en":70},[97,98],{"source":35,"section":61},{"source":35,"section":74},{"id":100,"disease":40,"label":101,"population":104,"type":106,"unit":30,"dose":107,"refs":108,"durationDays":111},"gerd-adult",{"fa":102,"en":103},"بزرگسال — ریفلاکس علامتی: ۲۰ mg روزانه تا ۴ هفته","Adults — symptomatic GERD: 20 mg daily up to 4 weeks",{"minAge":105},{"value":49,"unit":47},"fixed",{"perDose":29,"dosesPerDay":5},[109],{"source":35,"section":110},"2.1, Table 1",{"min":5,"max":65},{"id":113,"disease":114,"label":115,"population":118,"type":106,"unit":30,"dose":120,"refs":121,"durationDays":123},"du-adult","peptic-ulcer-disease",{"fa":116,"en":117},"بزرگسال — زخم اثنی‌عشر فعال: ۲۰ mg روزانه، ۴ هفته","Adults — active duodenal ulcer: 20 mg daily, 4 weeks",{"minAge":119},{"value":49,"unit":47},{"perDose":29,"dosesPerDay":5},[122],{"source":35,"section":110},{"min":65,"max":65},[125],{"id":126,"severity":127,"text":128,"refs":131},"hypersensitivity","block",{"fa":129,"en":130},"حساسیت به امپرازول یا بنزیمیدازول‌های جانشین‌شده؛ مصرف همزمان ریلپیویرین.","Hypersensitivity to the formulation or substituted benzimidazoles; rilpivirine-containing products.",[132],{"source":35,"section":133},"4",[],[],[],[],{"status":139,"reviewer":58,"date":58},"unverified",[141,147,152,156,161],{"regimen":39,"formulation":24,"input":142,"expect":145},{"ageYears":143,"weightKg":144},4,15,{"status":146},"blocked",{"regimen":39,"formulation":24,"input":148,"expect":151},{"ageYears":149,"weightKg":150},8,25,{"perDose":29,"tabletsPerDoseRounded":5},{"regimen":76,"formulation":24,"input":153,"expect":155},{"ageYears":50,"weightKg":154},30,{"perDose":29},{"regimen":100,"formulation":24,"input":157,"expect":160},{"ageYears":158,"weightKg":159},40,70,{"perDose":29},{"regimen":113,"formulation":24,"input":162,"expect":163},{"ageYears":158,"weightKg":159},{"perDose":29},[165],"A02BC01",{"status":167,"forms":168,"refs":193},"registered",[169,173,177,181,185,189],{"code":170,"en":171,"fa":172},"00931","OMEPRAZOLE 20MG CAP","کپسول امپرازول ۲۰ میلی‌گرم",{"code":174,"en":175,"fa":176},"07660","OMEPRAZOLE 40MG CAP","کپسول امپرازول ۴۰ میلی‌گرم",{"code":178,"en":179,"fa":180},"51518","OMEPRAZOLE POWDER, FOR SUSPENSION ORAL 20 mg","سوسپانسیون خوراکی امپرازول ۲۰ میلی‌گرم",{"code":182,"en":183,"fa":184},"52204","OMEPRAZOLE (AS SODIUM) INJECTION, POWDER, FOR SOLUTION PARENTERAL 40 mg","پودر برای تهیه محلول تزریقی امپرازول (معادل سدیم) ۴۰ میلی‌گرم",{"code":186,"en":187,"fa":188},"53120","OMEPRAZOLE \u002F SODIUM BICARBONATE POWDER, FOR SUSPENSION ORAL 20 mg\u002F1680 mg","سوسپانسیون خوراکی امپرازول \u002F سدیم بیکربنات ۲۰ میلی‌گرم \u002F ۱۶۸۰ میلی‌گرم",{"code":190,"en":191,"fa":192},"53121","OMEPRAZOLE \u002F SODIUM BICARBONATE POWDER, FOR SUSPENSION ORAL 40 mg\u002F1680 mg","سوسپانسیون خوراکی امپرازول \u002F سدیم بیکربنات ۴۰ میلی‌گرم \u002F ۱۶۸۰ میلی‌گرم",[194],{"source":195,"section":196,"url":197},"darooyab-generic","G-2621\u002FOmeprazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-2621\u002FOmeprazole",[199,203,207,210,213],{"kind":200,"url":201,"label":202},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=078490","ANDA078490",{"kind":204,"url":205,"label":206},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=c5e3a37a-f6e3-43d4-a8a9-54db6c271908","FDA Omeprazole",{"kind":208,"url":209,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa693050.html",{"kind":211,"url":212,"label":165},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A02BC01",{"kind":214,"url":197,"label":8},"darooyab",{"pregnancy":216,"lactation":225,"pediatric":233,"geriatric":240},{"level":217,"text":218,"quote":221,"refs":222},"caution",{"fa":219,"en":220},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no adequate and well-controlled studies with omeprazole in pregnant women.",[223],{"source":35,"section":224},"8.1",{"level":217,"text":226,"quote":229,"refs":230},{"fa":227,"en":228},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Limited data suggest omeprazole may be present in human milk.",[231],{"source":35,"section":232},"8.2",{"level":217,"text":234,"quote":237,"refs":238},{"fa":235,"en":236},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of omeprazole have been established in pediatric patients 2 to 16 years for the treatment of symptomatic GERD, treatment of EE due to acid-mediated GERD, and maintenance of healing of EE due to acid-mediated GERD.",[239],{"source":35,"section":63},{"level":241,"text":242,"quote":245,"refs":246},"ok",{"fa":243,"en":244},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","However, no dosage adjustment is necessary in the elderly [see Clinical Pharmacology (12.3) ].",[247],{"source":35,"section":248},"8.5",{"kind":250,"refs":251,"id":202},"ANDA",[252],{"source":35,"section":253},"SPL approval \u002F marketing category",1792191865171]