[{"data":1,"prerenderedAt":214},["ShallowReactive",2],{"drug-pantoprazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":43,"contraindications":91,"warnings":101,"renal":102,"monitoring":103,"interactions":104,"review":105,"examples":107,"atc":122,"iran":124,"links":156,"populations":176,"usApproval":209},"pantoprazole",1,{"fa":7,"en":8},"پنتوپرازول","Pantoprazole","alimentary-metabolism",{"fa":11,"en":12},"مهارکننده پمپ پروتون","Proton pump inhibitor",[14],{"name":15,"market":16},"Protonix","US",[18,7,19],"pantoprazol","PPI",[21,35],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-20","tablet","oral","20 mg delayed-release tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},20,"mg",false,[16],[32],{"source":33,"section":34},"fda-protonix","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-40","40 mg delayed-release tablet",{"amount":39,"unit":28,"perUnit":23,"scored":29},40,[16],[42],{"source":33,"section":34},[44,78],{"id":45,"disease":46,"label":47,"population":50,"type":55,"unit":28,"dose":56,"refs":63,"durationDays":68,"notes":70},"ee-child","erosive-esophagitis",{"fa":48,"en":49},"ازوفاژیت فرسایشی — ۵ سال به بالا، بر اساس وزن","Erosive esophagitis — 5 years and older, by weight",{"minAge":51,"minWeightKg":54},{"value":52,"unit":53},5,"year",15,"weightBand",{"weightBands":57},[58,61],{"minWeightKg":59,"maxWeightKg":60,"perDose":27,"dosesPerDay":5},14.99,39.99,{"minWeightKg":60,"maxWeightKg":62,"perDose":39,"dosesPerDay":5},null,[64,66],{"source":33,"section":65},"2.1, Table 1",{"source":33,"section":67},"8.4",{"min":5,"max":69},56,[71],{"text":72,"refs":75},{"fa":73,"en":74},"قرص خرد، جویده یا نصف نشود.","Do not split, chew or crush.",[76],{"source":33,"section":77},"2.2",{"id":79,"disease":46,"label":80,"population":83,"type":86,"unit":28,"dose":87,"refs":88,"durationDays":90},"ee-adult",{"fa":81,"en":82},"بزرگسال — ۴۰ mg روزانه تا ۸ هفته","Adults — 40 mg daily up to 8 weeks",{"minAge":84},{"value":85,"unit":53},17,"fixed",{"perDose":39,"dosesPerDay":5},[89],{"source":33,"section":65},{"min":5,"max":69},[92],{"id":93,"severity":94,"text":95,"refs":98},"hypersensitivity","block",{"fa":96,"en":97},"حساسیت به اجزا یا بنزیمیدازول‌های جانشین‌شده؛ مصرف همزمان ریلپیویرین.","Hypersensitivity to any component or substituted benzimidazoles; rilpivirine-containing products.",[99],{"source":33,"section":100},"4",[],[],[],[],{"status":106,"reviewer":62,"date":62},"unverified",[108,113,118],{"regimen":45,"formulation":22,"input":109,"expect":112},{"ageYears":110,"weightKg":111},8,25,{"perDose":27},{"regimen":45,"formulation":36,"input":114,"expect":117},{"ageYears":115,"weightKg":116},14,45,{"perDose":39},{"regimen":79,"formulation":36,"input":119,"expect":121},{"ageYears":39,"weightKg":120},70,{"tabletsPerDoseRounded":5},[123],"A02BC02",{"status":125,"forms":126,"refs":151},"registered",[127,131,135,139,143,147],{"code":128,"en":129,"fa":130},"16673","PANTOPRAZOLE 15MG CAP","کپسول پنتوپرازول ۱۵ میلی‌گرم",{"code":132,"en":133,"fa":134},"10031","PANTOPRAZOLE 20MG CAP","کپسول پنتوپرازول ۲۰ میلی‌گرم",{"code":136,"en":137,"fa":138},"02332","PANTOPRAZOLE 20MG TAB","قرص پنتوپرازول ۲۰ میلی‌گرم",{"code":140,"en":141,"fa":142},"10029","PANTOPRAZOLE 40MG CAP","کپسول پنتوپرازول ۴۰ میلی‌گرم",{"code":144,"en":145,"fa":146},"02336","PANTOPRAZOLE 40MG FOR INFUSION","محلول انفوزیون پنتوپرازول ۴۰ میلی‌گرم",{"code":148,"en":149,"fa":150},"02333","PANTOPRAZOLE 40MG TAB","قرص پنتوپرازول ۴۰ میلی‌گرم",[152],{"source":153,"section":154,"url":155},"darooyab-generic","G-2625\u002FPantoprazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-2625\u002FPantoprazole",[157,161,165,168,171,174],{"kind":158,"url":159,"label":160},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=020987","NDA020987",{"kind":162,"url":163,"label":164},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=08098cb2-c048-4640-f387-6beec4a38936","FDA Protonix",{"kind":166,"url":167,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601246.html",{"kind":166,"url":169,"label":170},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa619034.html","Pantoprazole Injection",{"kind":172,"url":173,"label":123},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A02BC02",{"kind":175,"url":155,"label":8},"darooyab",{"pregnancy":177,"lactation":186,"pediatric":194,"geriatric":201},{"level":178,"text":179,"quote":182,"refs":183},"caution",{"fa":180,"en":181},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Available data from published observational studies did not demonstrate an association of major malformations or other adverse pregnancy outcomes with pantoprazole.",[184],{"source":33,"section":185},"8.1",{"level":178,"text":187,"quote":190,"refs":191},{"fa":188,"en":189},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Pantoprazole has been detected in breast milk of a nursing mother after a single 40 mg oral dose of pantoprazole.",[192],{"source":33,"section":193},"8.2",{"level":178,"text":195,"quote":198,"refs":199},{"fa":196,"en":197},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of PROTONIX for short-term treatment (up to eight weeks) of EE associated with GERD have been established in pediatric patients 1 year through 16 years of age.",[200],{"source":33,"section":67},{"level":178,"text":202,"quote":205,"refs":206},{"fa":203,"en":204},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In short-term US clinical trials, EE healing rates in the 107 elderly patients (≥65 years old) treated with PROTONIX were similar to those found in patients under the age of 65.",[207],{"source":33,"section":208},"8.5",{"kind":210,"refs":211,"id":160},"NDA",[212],{"source":33,"section":213},"SPL approval \u002F marketing category",1792444700700]