[{"data":1,"prerenderedAt":177},["ShallowReactive",2],{"drug-praziquantel":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":74,"warnings":84,"renal":85,"monitoring":86,"interactions":87,"review":88,"examples":91,"atc":103,"iran":105,"links":121,"populations":138,"usApproval":172},"praziquantel",1,{"fa":7,"en":8},"پرازیکوانتل","Praziquantel","antiparasitic",{"fa":11,"en":12},"ضدانگل (ترماتود)","Anthelmintic (trematodes)",[14],{"name":15,"market":16},"Biltricide","US",[18,19,7],"biltricide","بیلتریساید",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-600","tablet","oral","600 mg tablet (three scores = four 150 mg segments)",{"amount":27,"unit":28,"perUnit":23,"scored":29},600,"mg",true,[16],[32],{"source":33,"section":34},"fda-praziquantel","3",[36,62],{"id":37,"disease":38,"label":39,"population":42,"type":45,"unit":28,"dose":46,"refs":49,"durationDays":52,"notes":53},"schisto","schistosomiasis",{"fa":40,"en":41},"شیستوزومیازیس — ۲۰ mg\u002Fkg سه بار در یک روز","Schistosomiasis — 20 mg\u002Fkg three times in one day",{"minAge":43},{"value":5,"unit":44},"year","weightBased",{"perKgPerDose":47,"intervalHours":48},20,8,[50],{"source":33,"section":51},"2.1",{"min":5,"max":5},[54],{"text":55,"refs":58},{"fa":56,"en":57},"فاصله ۴ تا ۶ ساعت، فقط یک روز؛ با آب و غذا. زیر ۶ سال قرص خرد شود.","4–6 h apart, one day only; with water during meals. Under 6 y the tablet may be crushed.",[59,60],{"source":33,"section":51},{"source":33,"section":61},"2.2",{"id":63,"disease":38,"label":64,"population":67,"type":45,"unit":28,"dose":69,"refs":71,"durationDays":73},"liver-fluke",{"fa":65,"en":66},"کلونورکیازیس\u002Fاوپیستورکیازیس — ۲۵ mg\u002Fkg سه بار در یک روز","Clonorchiasis\u002Fopisthorchiasis — 25 mg\u002Fkg three times in one day",{"minAge":68},{"value":5,"unit":44},{"perKgPerDose":70,"intervalHours":48},25,[72],{"source":33,"section":51},{"min":5,"max":5},[75],{"id":76,"severity":77,"text":78,"refs":81},"ci","block",{"fa":79,"en":80},"حساسیت؛ سیستیسرکوز چشمی؛ همراه القاکننده‌های قوی CYP450 مانند ریفامپین.","Hypersensitivity; ocular cysticercosis; with strong CYP450 inducers such as rifampin.",[82],{"source":33,"section":83},"4",[],[],[],[],{"status":89,"reviewer":90,"date":90},"unverified",null,[92,97],{"regimen":37,"formulation":22,"input":93,"expect":96},{"ageYears":94,"weightKg":95},10,30,{"perDose":27,"tabletsPerDoseRounded":5},{"regimen":63,"formulation":22,"input":98,"expect":100},{"ageYears":95,"weightKg":99},60,{"perDose":101,"tabletsPerDoseRounded":102},1500,2.5,[104],"P02BA01",{"status":106,"forms":107,"refs":116},"registered",[108,112],{"code":109,"en":110,"fa":111},"01041","PRAZIQUANTEL 600MG TAB","قرص پرازیکوانتل ۶۰۰ میلی‌گرم",{"code":113,"en":114,"fa":115},"18274","PRAZIQUANTIL 500MG  CAP.","کپسول پرازیکوانتیل ۵۰۰ میلی‌گرم .",[117],{"source":118,"section":119,"url":120},"darooyab-generic","G-260\u002FPraziquantel","https:\u002F\u002Fwww.darooyab.ir\u002FG-260\u002FPraziquantel",[122,126,130,133,136],{"kind":123,"url":124,"label":125},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=018714","NDA018714",{"kind":127,"url":128,"label":129},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=34ce1cdd-648e-4f1e-8512-bf3d4cc22eb9","FDA Biltricide",{"kind":131,"url":132,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa608048.html",{"kind":134,"url":135,"label":104},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=P02BA01",{"kind":137,"url":120,"label":8},"darooyab",{"pregnancy":139,"lactation":148,"pediatric":156,"geriatric":164},{"level":140,"text":141,"quote":144,"refs":145},"caution",{"fa":142,"en":143},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Published studies have not identified an association with Biltricide use during pregnancy and major birth defects, miscarriage or adverse maternal or fetal outcomes (see Data) .",[146],{"source":33,"section":147},"8.1",{"level":140,"text":149,"quote":152,"refs":153},{"fa":150,"en":151},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Limited data from published literature reports the presence of praziquantel in human milk at low concentrations.",[154],{"source":33,"section":155},"8.2",{"level":140,"text":157,"quote":160,"refs":161},{"fa":158,"en":159},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety of Biltricide in pediatric patients younger than 1 year of age has not been established.",[162],{"source":33,"section":163},"8.4",{"level":140,"text":165,"quote":168,"refs":169},{"fa":166,"en":167},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of Biltricide did not include a sufficient number of subjects ages 65 and over to determine whether they respond differently from younger subjects.",[170],{"source":33,"section":171},"8.5",{"kind":173,"refs":174,"id":125},"NDA",[175],{"source":33,"section":176},"SPL approval \u002F marketing category",1792191881495]