[{"data":1,"prerenderedAt":152},["ShallowReactive",2],{"drug-prednisone":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":51,"contraindications":67,"warnings":77,"renal":78,"monitoring":79,"interactions":80,"review":81,"examples":84,"atc":85,"iran":87,"links":94,"populations":112,"usApproval":147},"prednisone",1,{"fa":7,"en":8},"پردنیزون","Prednisone","systemic-hormones",{"fa":11,"en":12},"کورتیکواستروئید خوراکی","Oral corticosteroid",[14],{"name":15,"market":16},"Deltasone","US",[18,7,19],"deltasone","کورتون خوراکی",[21,35,43],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-5","tablet","oral","5 mg tablet (scored)",{"amount":27,"unit":28,"perUnit":23,"scored":29},5,"mg",true,[16],[32],{"source":33,"section":34},"fda-prednisone","How Supplied",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-10","10 mg tablet (scored)",{"amount":39,"unit":28,"perUnit":23,"scored":29},10,[16],[42],{"source":33,"section":34},{"id":44,"form":23,"route":24,"label":45,"concentration":46,"markets":48,"refs":49},"tab-20","20 mg tablet (scored)",{"amount":47,"unit":28,"perUnit":23,"scored":29},20,[16],[50],{"source":33,"section":34},[52],{"id":53,"disease":54,"label":55,"population":58,"type":59,"unit":28,"dose":60,"refs":64},"adult","corticosteroid-responsive",{"fa":56,"en":57},"بیماری‌های پاسخ‌ده به کورتون","Corticosteroid-responsive conditions",{},"notCalculated",{"reason":61},{"fa":62,"en":63},"دوز اولیه ۵ تا ۶۰ mg\u002Fday بسته به بیماری؛ سپس به کمترین دوز مؤثر کاهش و در درمان طولانی به‌تدریج قطع شود.","Initial 5–60 mg\u002Fday depending on the disease; then reduce to the lowest effective dose and taper after long-term use.",[65],{"source":33,"section":66},"Dosage and Administration",[68],{"id":69,"severity":70,"text":71,"refs":74},"ci","block",{"fa":72,"en":73},"عفونت قارچی سیستمیک؛ حساسیت.","Systemic fungal infections; hypersensitivity.",[75],{"source":33,"section":76},"Contraindications",[],[],[],[],{"status":82,"reviewer":83,"date":83},"unverified",null,[],[86],"H02AB07",{"status":88,"refs":89},"not-found",[90],{"source":91,"section":92,"url":93},"darooyab-generic","G-2124\u002FPred-nisone","https:\u002F\u002Fwww.darooyab.ir\u002FG-2124\u002FPred-nisone",[95,99,103,106,109],{"kind":96,"url":97,"label":98},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=080292","ANDA080292",{"kind":100,"url":101,"label":102},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=fec09050-5ac2-451b-a2b9-5a21b2def212","FDA Prednisone",{"kind":104,"url":105,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601102.html",{"kind":107,"url":108,"label":86},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=H02AB07",{"kind":110,"url":93,"label":111},"darooyab","Pred-nisone",{"pregnancy":113,"lactation":122,"pediatric":131,"geriatric":139},{"level":114,"text":115,"quote":118,"refs":119},"caution",{"fa":116,"en":117},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[120],{"source":33,"section":121},"Pregnancy",{"level":123,"text":124,"quote":127,"refs":128},"avoid",{"fa":125,"en":126},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions in nursing infants from corticosteroids, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[129],{"source":33,"section":130},"Nursing Mothers",{"level":114,"text":132,"quote":135,"refs":136},{"fa":133,"en":134},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The efficacy and safety of corticosteroids in the pediatric population are based on the well-established course of effect of corticosteroids, which is similar in pediatric and adult populations.",[137],{"source":33,"section":138},"Pediatric Use",{"level":114,"text":140,"quote":143,"refs":144},{"fa":141,"en":142},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.",[145],{"source":33,"section":146},"Geriatric Use",{"kind":148,"refs":149,"id":98},"ANDA",[150],{"source":33,"section":151},"SPL approval \u002F marketing category",1792191871745]