[{"data":1,"prerenderedAt":215},["ShallowReactive",2],{"drug-prochlorperazine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":45,"contraindications":104,"warnings":124,"renal":125,"monitoring":126,"interactions":127,"review":128,"examples":131,"atc":149,"iran":151,"links":158,"populations":175,"usApproval":210},"prochlorperazine",1,{"fa":7,"en":8},"پروکلرپرازین","Prochlorperazine","nervous-system",{"fa":11,"en":12},"فنوتیازین ضدتهوع","Phenothiazine antiemetic",[14],{"name":15,"market":16},"Compazine","US",[18,19,20,7],"compazine","stemetil","استمتیل",[22,36],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-5","tablet","oral","5 mg tablet (scored)",{"amount":28,"unit":29,"perUnit":24,"scored":30},5,"mg",true,[16],[33],{"source":34,"section":35},"fda-prochlorperazine","How Supplied",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":42,"refs":43},"tab-10","10 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":41},10,false,[16],[44],{"source":34,"section":35},[46,73],{"id":47,"disease":48,"label":49,"population":52,"type":56,"unit":29,"dose":57,"refs":59,"limits":62,"notes":66},"adult","nausea-vomiting",{"fa":50,"en":51},"تهوع و استفراغ شدید — بزرگسال: ۵ یا ۱۰ mg سه یا چهار بار","Severe nausea and vomiting — adults: 5 or 10 mg three or four times daily",{"minAge":53},{"value":54,"unit":55},18,"year","fixed",{"perDose":28,"perDoseMax":40,"dosesPerDay":58},3,[60],{"source":34,"section":61},"Dosage and Administration - Adults",{"maxPerDay":63,"refs":64},40,[65],{"source":34,"section":61},[67],{"text":68,"refs":71},{"fa":69,"en":70},"بالای ۴۰ mg\u002Fday فقط در موارد مقاوم.","Above 40 mg\u002Fday only in resistant cases.",[72],{"source":34,"section":61},{"id":74,"disease":48,"label":75,"population":78,"type":83,"unit":29,"dose":84,"refs":94,"notes":97},"child",{"fa":76,"en":77},"تهوع و استفراغ شدید — کودک ۲ سال به بالا و ۹ kg به بالا: بر اساس وزن","Severe nausea and vomiting — child ≥2 y and ≥20 lb: by weight",{"minAge":79,"maxAge":81,"minWeightKg":82},{"value":80,"unit":55},2,{"value":54,"unit":55},9.07,"weightBand",{"weightBands":85},[86,90,92],{"minWeightKg":87,"maxWeightKg":88,"perDose":89,"dosesPerDay":5},9.06,13.6,2.5,{"minWeightKg":88,"maxWeightKg":91,"perDose":89,"dosesPerDay":80},18.13,{"minWeightKg":91,"maxWeightKg":93,"perDose":89,"dosesPerDay":58},38.56,[95],{"source":34,"section":96},"Dosage and Administration - Children",[98],{"text":99,"refs":102},{"fa":100,"en":101},"۲۰ تا ۲۹ پوند: ۲٫۵ mg یک یا دو بار (حداکثر ۷٫۵ mg\u002Fday)؛ ۳۰ تا ۳۹: ۲٫۵ mg دو یا سه بار (حداکثر ۱۰)؛ ۴۰ تا ۸۵: ۲٫۵ mg سه بار یا ۵ mg دو بار (حداکثر ۱۵). تبدیل پوند به kg را Doz انجام داده. کودکان به عوارض اکستراپیرامیدال حساس‌ترند.","20–29 lb: 2.5 mg once or twice daily (max 7.5 mg\u002Fday); 30–39: 2.5 mg 2–3 times (max 10); 40–85: 2.5 mg three times or 5 mg twice (max 15). Pound-to-kg conversion by Doz. Children are more prone to extrapyramidal reactions.",[103],{"source":34,"section":96},[105,115],{"id":74,"severity":106,"rule":107,"text":109,"refs":112},"block",{"maxAge":108},{"value":80,"unit":55},{"fa":110,"en":111},"زیر ۲ سال یا زیر ۲۰ پوند استفاده نشود؛ نه در جراحی کودکان.","Do not use under 2 years or under 20 lb; not in pediatric surgery.",[113],{"source":34,"section":114},"Contraindications",{"id":116,"severity":117,"text":118,"refs":121},"boxed","warn",{"fa":119,"en":120},"هشدار جعبه‌ای: افزایش مرگ در سالمندان مبتلا به سایکوز ناشی از دمانس.","Boxed warning: increased mortality in elderly patients with dementia-related psychosis.",[122],{"source":34,"section":123},"Boxed Warning",[],[],[],[],{"status":129,"reviewer":130,"date":130},"unverified",null,[132,137,143],{"regimen":47,"formulation":23,"input":133,"expect":136},{"ageYears":134,"weightKg":135},30,70,{"perDose":28,"upperPerDose":40},{"regimen":74,"formulation":23,"input":138,"expect":141},{"ageYears":139,"weightKg":140},4,15,{"perDose":89,"tabletsPerDoseRounded":142,"perDay":28},0.5,{"regimen":74,"formulation":23,"input":144,"expect":147},{"ageYears":145,"weightKg":146},8,25,{"perDay":148},7.5,[150],"N05AB04",{"status":152,"refs":153},"not-found",[154],{"source":155,"section":156,"url":157},"darooyab-generic","G-1334\u002FProchlorperazine","https:\u002F\u002Fwww.darooyab.ir\u002FG-1334\u002FProchlorperazine",[159,163,167,170,173],{"kind":160,"url":161,"label":162},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=040268","ANDA040268",{"kind":164,"url":165,"label":166},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=3d28dab2-0264-482e-b99d-f56a9314b8a5","FDA Prochlorperazine",{"kind":168,"url":169,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682116.html",{"kind":171,"url":172,"label":150},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N05AB04",{"kind":174,"url":157,"label":8},"darooyab",{"pregnancy":176,"lactation":185,"pediatric":193,"geriatric":202},{"level":177,"text":178,"quote":181,"refs":182},"caution",{"fa":179,"en":180},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Prochlorperazine Maleate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[183],{"source":34,"section":184},"Precautions\u002FWarnings – Usage in Pregnancy",{"level":177,"text":186,"quote":189,"refs":190},{"fa":187,"en":188},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Caution should be exercised when prochlorperazine is administered to a nursing woman.",[191],{"source":34,"section":192},"Precautions\u002FWarnings – Nursing Mothers",{"level":194,"text":195,"quote":198,"refs":199},"contraindicated",{"fa":196,"en":197},"برچسب: در کودکان زیر سن مشخص منع مصرف دارد.","Label: contraindicated in children below a stated age.","Do not use in pediatric patients under 2 years of age or under 20 lbs.",[200],{"source":34,"section":201},"CONTRAINDICATIONS",{"level":203,"text":204,"quote":207,"refs":208},"avoid",{"fa":205,"en":206},"برچسب: در سالمندان هشدار جدی یا پرهیز.","Label: serious warning or avoid in older adults.","Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.",[209],{"source":34,"section":123},{"kind":211,"refs":212,"id":162},"ANDA",[213],{"source":34,"section":214},"SPL approval \u002F marketing category",1792440737240]