[{"data":1,"prerenderedAt":166},["ShallowReactive",2],{"drug-solifenacin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":43,"contraindications":69,"warnings":79,"renal":80,"monitoring":81,"interactions":82,"review":83,"examples":86,"atc":92,"iran":94,"links":110,"populations":127,"usApproval":161},"solifenacin",1,{"fa":7,"en":8},"سولیفناسین","Solifenacin","genitourinary-sex-hormones",{"fa":11,"en":12},"آنتی‌موسکارینی ادراری","Urinary antimuscarinic",[14],{"name":15,"market":16},"Vesicare","US",[18,19,7],"vesicare","وزیکر",[21,35],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-5","tablet","oral","5 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},5,"mg",false,[16],[32],{"source":33,"section":34},"fda-solifenacin","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-10","10 mg tablet",{"amount":39,"unit":28,"perUnit":23,"scored":29},10,[16],[42],{"source":33,"section":34},[44],{"id":45,"disease":46,"label":47,"population":50,"type":54,"unit":28,"dose":55,"refs":56,"notes":61},"oab","overactive-bladder",{"fa":48,"en":49},"مثانه بیش‌فعال — ۵ mg یک بار (تا ۱۰ mg)","Overactive bladder — 5 mg once daily (up to 10 mg)",{"minAge":51},{"value":52,"unit":53},18,"year","fixed",{"perDose":27,"perDoseMax":39,"dosesPerDay":5},[57,59],{"source":33,"section":58},"2.1",{"source":33,"section":60},"2",[62],{"text":63,"refs":66},{"fa":64,"en":65},"CrCl کمتر از ۳۰: حداکثر ۵ mg.","CrCl \u003C30: max 5 mg.",[67],{"source":33,"section":68},"2.2",[70],{"id":71,"severity":72,"text":73,"refs":76},"ci","block",{"fa":74,"en":75},"احتباس ادرار یا معده؛ گلوکوم زاویه بسته کنترل‌نشده؛ حساسیت.","Urinary or gastric retention; uncontrolled narrow-angle glaucoma; hypersensitivity.",[77],{"source":33,"section":78},"4",[],[],[],[],{"status":84,"reviewer":85,"date":85},"unverified",null,[87],{"regimen":45,"formulation":22,"input":88,"expect":91},{"ageYears":89,"weightKg":90},60,70,{"perDose":27,"upperPerDose":39},[93],"G04BD08",{"status":95,"forms":96,"refs":105},"registered",[97,101],{"code":98,"en":99,"fa":100},"07559","SOLIFENACIN 10MG TAB","قرص سولیفناسین ۱۰ میلی‌گرم",{"code":102,"en":103,"fa":104},"07558","SOLIFENACIN 5MG TAB","قرص سولیفناسین ۵ میلی‌گرم",[106],{"source":107,"section":108,"url":109},"darooyab-generic","G-923\u002FSolifenacin","https:\u002F\u002Fwww.darooyab.ir\u002FG-923\u002FSolifenacin",[111,115,119,122,125],{"kind":112,"url":113,"label":114},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=204374","ANDA204374",{"kind":116,"url":117,"label":118},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=fbd6e753-1ed2-418a-8667-c674b215eabb","FDA Solifenacin",{"kind":120,"url":121,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa605019.html",{"kind":123,"url":124,"label":93},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G04BD08",{"kind":126,"url":109,"label":8},"darooyab",{"pregnancy":128,"lactation":137,"pediatric":145,"geriatric":153},{"level":129,"text":130,"quote":133,"refs":134},"caution",{"fa":131,"en":132},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no studies with the use of solifenacin succinate in pregnant women to inform a drug-associated risk of major birth defects, miscarriages, or adverse maternal or fetal outcomes.",[135],{"source":33,"section":136},"8.1",{"level":129,"text":138,"quote":141,"refs":142},{"fa":139,"en":140},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There is no information on the presence of solifenacin in human milk, the effects on the breastfed child, or the effects on milk production.",[143],{"source":33,"section":144},"8.2",{"level":129,"text":146,"quote":149,"refs":150},{"fa":147,"en":148},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of solifenacin succinate tablets have not been established in pediatric patients.",[151],{"source":33,"section":152},"8.4",{"level":129,"text":154,"quote":157,"refs":158},{"fa":155,"en":156},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In placebo-controlled clinical studies, similar safety and effectiveness were observed between geriatric patients (623 patients ≥ 65 years and 189 patients ≥ 75 years) and younger adult patients (1188 patients \u003C 65 years) treated with solifenacin succinate tablets.",[159],{"source":33,"section":160},"8.5",{"kind":162,"refs":163,"id":114},"ANDA",[164],{"source":33,"section":165},"SPL approval \u002F marketing category",1792191871084]