[{"data":1,"prerenderedAt":188},["ShallowReactive",2],{"drug-theophylline-g":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":19,"formulations":23,"regimens":36,"contraindications":55,"warnings":77,"renal":85,"monitoring":86,"interactions":87,"review":88,"examples":91,"atc":92,"iran":94,"links":134,"populations":149,"usApproval":183},"theophylline-g",1,{"fa":7,"en":8},"تئوفیلین جی (تئوفیلین + گایافنزین)","Theophylline G (theophylline + guaifenesin)","respiratory",{"fa":11,"en":12},"برونکودیلاتور + خلط‌آور","Bronchodilator + expectorant",[14,17],{"name":15,"market":16},"Theochal-G (Alborz Darou)","IR",{"name":18,"market":16},"Theozin Lito (Kharazmi)",[20,21,22],"تئوفیلین جی","تئوکال جی","theophylline g",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":31,"refs":32},"syr-120","syrup","oral","Theophylline + guaifenesin syrup 120 mL (strength per 5 mL not confirmed)",{"amount":5,"unit":30,"perVolumeMl":5},"mL",[16],[33],{"source":34,"section":35},"ir-darooyab-theophylline-g","اشکال دارویی",[37],{"id":38,"disease":38,"label":39,"population":42,"type":43,"unit":44,"dose":45,"refs":49},"asthma",{"fa":40,"en":41},"آسم همراه خلط غلیظ","Asthma with thick secretions",{},"notCalculated","mg",{"reason":46},{"fa":47,"en":48},"مقدار تئوفیلین و گایافنزین در هر ۵ mL در منابع در دسترس تأیید نشد؛ دوز mL قابل محاسبه نیست. دوز تئوفیلین کودکان را از صفحه تئوفیلین (برچسب FDA) و غلظت را از بروشور فرآورده بگیرید. در کودکان بالای ۲ سال فقط با تشخیص پزشک و دوز وزنی.","Theophylline and guaifenesin amounts per 5 mL could not be confirmed in accessible sources; mL dose cannot be calculated. Take theophylline pediatric dosing from the theophylline page (FDA label) and the strength from the product leaflet. In children over 2 years only on medical advice with weight-based dosing.",[50,52],{"source":34,"section":51},"دوز کودکان",{"source":53,"section":54},"fda-theophylline-sol","Dosage and Administration, Table V",[56,65],{"id":57,"severity":58,"text":59,"refs":62},"absolute","block",{"fa":60,"en":61},"حساسیت به مشتقات گزانتین یا گایافنزین.","Hypersensitivity to xanthines or guaifenesin.",[63],{"source":34,"section":64},"موارد منع مصرف",{"id":66,"severity":67,"rule":68,"text":72,"refs":75},"under-2","warn",{"maxAge":69},{"value":70,"unit":71},2,"year",{"fa":73,"en":74},"در شیرخواران و کودکان زیر ۲ سال توصیه نمی‌شود.","Not recommended in infants and children under 2 years.",[76],{"source":34,"section":51},[78],{"text":79,"refs":82},{"fa":80,"en":81},"پنجره درمانی بسیار باریک؛ پایش سطح سرمی. در عفونت ویروسی و تب بالا کلیرانس افت می‌کند. سیپروفلوکساسین، اریترومایسین و کلاریترومایسین سطح را بالا می‌برند (گاه کاهش دوز تا ۵۰٪).","Very narrow therapeutic window; monitor serum levels. Clearance falls during viral infection and high fever. Ciprofloxacin, erythromycin, clarithromycin raise levels (dose reduction up to 50%).",[83],{"source":34,"section":84},"هشدارها",[],[],[],{"status":89,"reviewer":90,"date":90},"unverified",null,[],[93],"R03DA54",{"status":95,"forms":96,"refs":129},"iran-only",[97,101,105,109,113,117,121,125],{"code":98,"en":99,"fa":100},"02403","THEOPHYLLINE 100MG RET TAB","قرص تئوفیلین ۱۰۰ میلی‌گرم RET",{"code":102,"en":103,"fa":104},"01691","THEOPHYLLINE 100MG TAB","قرص تئوفیلین ۱۰۰ میلی‌گرم",{"code":106,"en":107,"fa":108},"02203","THEOPHYLLINE 200MG RET CAP","کپسول تئوفیلین ۲۰۰ میلی‌گرم RET",{"code":110,"en":111,"fa":112},"01209","THEOPHYLLINE 200MG RET TAB","قرص تئوفیلین ۲۰۰ میلی‌گرم RET",{"code":114,"en":115,"fa":116},"01210","THEOPHYLLINE 200MG TAB","قرص تئوفیلین ۲۰۰ میلی‌گرم",{"code":118,"en":119,"fa":120},"52437","THEOPHYLLINE CAPSULE, COATED, EXTENDED RELEASE ORAL 100 mg","کپسول آهسته‌رهش تئوفیلین ۱۰۰ میلی‌گرم",{"code":122,"en":123,"fa":124},"52438","THEOPHYLLINE CAPSULE, COATED, EXTENDED RELEASE ORAL 300 mg","کپسول آهسته‌رهش تئوفیلین ۳۰۰ میلی‌گرم",{"code":126,"en":127,"fa":128},"52439","THEOPHYLLINE CAPSULE, COATED, EXTENDED RELEASE ORAL 400 mg","کپسول آهسته‌رهش تئوفیلین ۴۰۰ میلی‌گرم",[130],{"source":131,"section":132,"url":133},"darooyab-generic","G-1496\u002FTheophylline","https:\u002F\u002Fwww.darooyab.ir\u002FG-1496\u002FTheophylline",[135,139,143,146],{"kind":136,"url":137,"label":138},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=091156","ANDA091156",{"kind":140,"url":141,"label":142},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=1b685384-5d96-46fa-b93b-e96538a2cfe7","FDA Theophylline sol",{"kind":144,"url":145,"label":93},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R03DA54",{"kind":147,"url":133,"label":148},"darooyab","Theophylline",{"pregnancy":150,"lactation":159,"pediatric":167,"geriatric":175},{"level":151,"text":152,"quote":155,"refs":156},"caution",{"fa":153,"en":154},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","There are no adequate and well controlled studies in pregnant women.",[157],{"source":53,"section":158},"Precautions\u002FWarnings – Pregnancy",{"level":151,"text":160,"quote":163,"refs":164},{"fa":161,"en":162},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Theophylline is excreted into breast milk and may cause irritability or other signs of mild toxicity in nursing human infants.",[165],{"source":53,"section":166},"Precautions\u002FWarnings – Nursing Mothers",{"level":151,"text":168,"quote":171,"refs":172},{"fa":169,"en":170},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Theophylline is safe and effective for the approved indications in pediatric patients (See INDICATIONS AND USAGE ).",[173],{"source":53,"section":174},"Precautions\u002FWarnings – Pediatric Use",{"level":151,"text":176,"quote":179,"refs":180},{"fa":177,"en":178},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Theophylline clearance is reduced in patients greater than 60 years of age, resulting in increased serum theophylline concentrations in response to a given theophylline dose.",[181],{"source":53,"section":182},"Precautions\u002FWarnings – Geriatric Use",{"kind":184,"refs":185,"id":138},"ANDA",[186],{"source":53,"section":187},"SPL approval \u002F marketing category",1792440742211]