[{"data":1,"prerenderedAt":244},["ShallowReactive",2],{"drug-trifluoperazine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":59,"contraindications":126,"warnings":145,"renal":146,"monitoring":147,"interactions":148,"review":149,"examples":152,"atc":166,"iran":168,"links":196,"populations":213,"usApproval":239},"trifluoperazine",1,{"fa":7,"en":8},"تری‌فلوپرازین","Trifluoperazine","nervous-system",{"fa":11,"en":12},"فنوتیازین (آنتی‌سایکوتیک تیپیک)","Phenothiazine antipsychotic",[14],{"name":15,"market":16},"Stelazine","US",[18,19,20],"stelazine","استلازین","تری فلوپرازین",[22,35,43,51],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":30,"refs":31},"tab-1","tablet","oral","1 mg tablet",{"amount":5,"unit":28,"perUnit":24,"scored":29},"mg",false,[16],[32],{"source":33,"section":34},"fda-trifluoperazine","How Supplied",{"id":36,"form":24,"route":25,"label":37,"concentration":38,"markets":40,"refs":41},"tab-2","2 mg tablet",{"amount":39,"unit":28,"perUnit":24,"scored":29},2,[16],[42],{"source":33,"section":34},{"id":44,"form":24,"route":25,"label":45,"concentration":46,"markets":48,"refs":49},"tab-5","5 mg tablet",{"amount":47,"unit":28,"perUnit":24,"scored":29},5,[16],[50],{"source":33,"section":34},{"id":52,"form":24,"route":25,"label":53,"concentration":54,"markets":56,"refs":57},"tab-10","10 mg tablet",{"amount":55,"unit":28,"perUnit":24,"scored":29},10,[16],[58],{"source":33,"section":34},[60,88,106],{"id":61,"disease":62,"label":63,"population":66,"type":70,"unit":28,"dose":71,"refs":72,"limits":75,"durationDays":79,"notes":81},"anx","anxiety",{"fa":64,"en":65},"اضطراب غیرسایکوتیک — ۱ یا ۲ mg دو بار","Non-psychotic anxiety — 1 or 2 mg twice daily",{"minAge":67},{"value":68,"unit":69},18,"year","fixed",{"perDose":5,"perDoseMax":39,"dosesPerDay":39},[73],{"source":33,"section":74},"Dosage and Administration-Adults",{"maxPerDay":76,"refs":77},6,[78],{"source":33,"section":74},{"min":5,"max":80},84,[82],{"text":83,"refs":86},{"fa":84,"en":85},"حداکثر ۶ mg\u002Fday و حداکثر ۱۲ هفته.","Max 6 mg\u002Fday and no longer than 12 weeks.",[87],{"source":33,"section":74},{"id":89,"disease":90,"label":91,"population":94,"type":70,"unit":28,"dose":96,"refs":97,"notes":99},"scz","schizophrenia",{"fa":92,"en":93},"اسکیزوفرنی — شروع ۲ تا ۵ mg دو بار","Schizophrenia — start 2–5 mg twice daily",{"minAge":95},{"value":68,"unit":69},{"perDose":39,"perDoseMax":47,"dosesPerDay":39},[98],{"source":33,"section":74},[100],{"text":101,"refs":104},{"fa":102,"en":103},"بیشتر بیماران با ۱۵ تا ۲۰ mg\u002Fday؛ گاهی ۴۰ mg یا بیشتر.","Most respond at 15–20 mg\u002Fday; a few need 40 mg or more.",[105],{"source":33,"section":74},{"id":107,"disease":90,"label":108,"population":111,"type":70,"unit":28,"dose":115,"refs":116,"notes":119},"scz-child",{"fa":109,"en":110},"اسکیزوفرنی — ۶ تا ۱۲ سال (بستری\u002Fتحت نظر): ۱ mg یک یا دو بار","Schizophrenia — 6–12 y (supervised): 1 mg once or twice daily",{"minAge":112,"maxAge":113},{"value":76,"unit":69},{"value":114,"unit":69},13,{"perDose":5,"dosesPerDay":5},[117],{"source":33,"section":118},"Dosage and Administration-Schizophrenia in Children",[120],{"text":121,"refs":124},{"fa":122,"en":123},"معمولاً نیازی به بیش از ۱۵ mg\u002Fday نیست.","Usually not necessary to exceed 15 mg\u002Fday.",[125],{"source":33,"section":118},[127,136],{"id":128,"severity":129,"text":130,"refs":133},"ci","block",{"fa":131,"en":132},"حساسیت به فنوتیازین‌ها؛ کما یا دپرسیون شدید CNS؛ دیسکرازی خونی، سرکوب مغز استخوان، آسیب کبدی.","Hypersensitivity to phenothiazines; coma or marked CNS depression; blood dyscrasias, marrow depression, liver damage.",[134],{"source":33,"section":135},"Contraindications",{"id":137,"severity":138,"text":139,"refs":142},"dementia","warn",{"fa":140,"en":141},"هشدار جعبه‌ای: افزایش مرگ در سالمندان مبتلا به سایکوز ناشی از دمانس.","Boxed warning: increased mortality in elderly patients with dementia-related psychosis.",[143],{"source":33,"section":144},"Boxed Warning",[],[],[],[],{"status":150,"reviewer":151,"date":151},"unverified",null,[153,158,162],{"regimen":61,"formulation":23,"input":154,"expect":157},{"ageYears":155,"weightKg":156},40,70,{"perDose":5,"upperPerDose":39},{"regimen":89,"formulation":36,"input":159,"expect":161},{"ageYears":160,"weightKg":156},30,{"perDose":39},{"regimen":107,"formulation":23,"input":163,"expect":165},{"ageYears":164,"weightKg":160},9,{"perDose":5},[167],"N05AB06",{"status":169,"forms":170,"refs":191},"registered",[171,175,179,183,187],{"code":172,"en":173,"fa":174},"02191","TRIFLUOPERAZINE 10MG TAB","قرص تری‌فلوئوپرازین ۱۰ میلی‌گرم",{"code":176,"en":177,"fa":178},"01253","TRIFLUOPERAZINE 1MG TAB","قرص تری‌فلوئوپرازین ۱ میلی‌گرم",{"code":180,"en":181,"fa":182},"01254","TRIFLUOPERAZINE 1MG\u002F1ML AMP","آمپول تری‌فلوئوپرازین ۱ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":184,"en":185,"fa":186},"01255","TRIFLUOPERAZINE 2MG TAB","قرص تری‌فلوئوپرازین ۲ میلی‌گرم",{"code":188,"en":189,"fa":190},"01256","TRIFLUOPERAZINE 5MG TAB","قرص تری‌فلوئوپرازین ۵ میلی‌گرم",[192],{"source":193,"section":194,"url":195},"darooyab-generic","G-1362\u002FTrifluoperazine","https:\u002F\u002Fwww.darooyab.ir\u002FG-1362\u002FTrifluoperazine",[197,201,205,208,211],{"kind":198,"url":199,"label":200},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=040209","ANDA040209",{"kind":202,"url":203,"label":204},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=f742a579-411a-4140-91c4-edc735d638fa","FDA Trifluoperazine",{"kind":206,"url":207,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682121.html",{"kind":209,"url":210,"label":167},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N05AB06",{"kind":212,"url":195,"label":8},"darooyab",{"pregnancy":214,"lactation":223,"geriatric":232},{"level":215,"text":216,"quote":219,"refs":220},"caution",{"fa":217,"en":218},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Trifluoperazine hydrochloride should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[221],{"source":33,"section":222},"Pregnancy",{"level":224,"text":225,"quote":228,"refs":229},"avoid",{"fa":226,"en":227},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions in nursing infants from trifluoperazine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[230],{"source":33,"section":231},"Nursing Mothers",{"level":224,"text":233,"quote":236,"refs":237},{"fa":234,"en":235},"برچسب: در سالمندان هشدار جدی یا پرهیز.","Label: serious warning or avoid in older adults.","Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.",[238],{"source":33,"section":144},{"kind":240,"refs":241,"id":200},"ANDA",[242],{"source":33,"section":243},"SPL approval \u002F marketing category",1792191877358]