Crohn’s disease

Crohn’s / UC — adult: 160 mg day 1, 80 mg day 15, then 40 mg every other week

Mild–moderate active Crohn’s — adult: 9 mg every morning up to 8 weeks

Active Crohn’s — child 8–17 y >25 kg: 9 mg up to 8 weeks, then 6 mg for 2 weeks

Maintenance Crohn disease — 400 mg every 4 weeks

Crohn’s — adults and children ≥6 y: 5 mg/kg per infusion (weeks 0, 2, 6, then every 8 weeks)

Moderate–severe Crohn disease, adults — 300 mg IV every 4 weeks (no concomitant immunosuppressants or TNF inhibitors)

Crohn disease, adults — induction 600 mg IV (over ≥1 h) at weeks 0, 4 and 8

Maintenance Crohn or UC — 180 or 360 mg SC every 8 weeks

Crohn’s — induction 45 mg daily for 12 weeks, maintenance 15 mg (up to 30)

Crohn’s / UC — single IV induction by weight: ≤55 kg 260, 55–85 → 390, >85 kg → 520 mg

Moderate–severe Crohn disease, adults — 300 mg IV at weeks 0, 2 and 6, then every 8 weeks