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Gout
Gout · ICD-10: M10.9
Symptoms
- • Sudden severe joint pain, often at night
- • Usually one or a few joints (often the big toe)
- • Warm, red, very tender joint
- • Sometimes fever
- • Attacks last days and may recur
Drugs and regimens
Allopurinol⚠ Unverified
Gout (urate lowering) — start 100 mg/day, weekly increases
Colchicine⚠ Unverified
Gout flare — 1.2 mg, then 0.6 mg one hour later
Colchicine⚠ Unverified
Gout flare prophylaxis — >16 y: 0.6 mg once or twice daily
Etoricoxib⚠ Unverified
Acute gout — 120 mg once daily, max 8 days
Febuxostat⚠ Unverified
Chronic hyperuricaemia in gout — start 40 mg once daily (up to 80 mg)
Indomethacin⚠ Unverified
Acute gouty arthritis — 50 mg three times daily
Naproxen⚠ Unverified
Acute gout — 750 mg, then 250 mg every 8 h
Pegloticase⚠ Unverified
Refractory chronic gout, adults — 8 mg IV infusion every 2 weeks with methotrexate 15 mg weekly
Probenecid⚠ Unverified
Hyperuricaemia of gout (between attacks) — 250 mg twice daily for one week, then 500 mg twice daily