HIV-1 infection (treatment)

HIV-1 adult — 300 mg twice daily or 600 mg once daily

Children ≥14 kg (scored tablet) — once daily: 300 / 450 / 600 mg by weight

HIV-1 adult — 300 mg + ritonavir 100 mg once daily with food

HIV-1 (complete regimen) — ≥25 kg: one 50/200/25 mg tablet daily; 14–<25 kg: one 30/120/15 mg tablet

Virologically suppressed HIV-1 (≥12 y, ≥35 kg) — gluteal IM injections monthly or every 2 months by a healthcare provider

HIV-1 naive or no darunavir resistance — 800 mg + ritonavir 100 mg once daily with food

HIV-1 with ≥1 darunavir resistance substitution, or pregnancy — 600 mg + ritonavir 100 mg twice daily with food

HIV-1 (INSTI-naive) — 50 mg once daily

HIV-1 with certain inducers (efavirenz, rifampin…) or INSTI resistance — 50 mg twice daily

Child ≥14 kg (tablets) — 14 to <20 kg: 40 mg; ≥20 kg: 50 mg once daily

HIV-1 — adults and children ≥40 kg: 600 mg once daily, empty stomach, preferably at bedtime

HIV-1 — adult: 150 mg twice daily or 300 mg once daily

Child ≥14 kg (scored 150 mg tablet) — once daily: 150 / 225 / 300 mg by weight

HIV-1 — adult: 400 mg twice daily (or 1200 mg once daily if treatment-naive)

HIV-1 naive or suppressed — 1200 mg (2 × 600 mg) once daily

HIV-1 treatment-naive — ≥25 kg: 25 mg once daily with a meal

HIV-1 — adult: 300 mg twice daily

Child 4 to <9 kg — 12 mg/kg twice daily

Child 9 to <30 kg — 9 mg/kg twice daily

Child ≥30 kg — 300 mg twice daily

Prevention of maternal-fetal transmission — mother (>14 weeks): 100 mg five times daily until labour

Neonate (prophylaxis) — 2 mg/kg orally every 6 h from within 12 h of birth to 6 weeks