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Functional bowel / irritable bowel syndrome
Functional bowel / irritable bowel syndrome · ICD-10: K58.9
Symptoms
- • Abdominal pain and cramps
- • Bloating and gas
- • Fullness
- • Change in bowel habits (diarrhea or constipation)
Drugs and regimens
Alosetron⚠ Unverified
Severe diarrhoea-predominant IBS in women unresponsive to conventional therapy — start 0.5 mg twice daily; after 4 weeks up to 1 mg twice daily
Chlordiazepoxide/clidinium⚠ Unverified
IBS/peptic ulcer (adjunct) — start no more than 2 capsules daily
Dicyclomine⚠ Unverified
Adults — 20 mg four times daily
Dicyclomine⚠ Unverified
Children
Eluxadoline⚠ Unverified
IBS with diarrhoea, adults — 100 mg twice daily with food
Hyoscine butylbromide⚠ Unverified
IBS — start 10 mg three times daily (up to 20 mg four times daily)
Linaclotide⚠ Unverified
IBS with constipation — adult: 290 mcg once daily
Linaclotide⚠ Unverified
IBS-C — child ≥7 y: 145 mcg once daily
Lubiprostone⚠ Unverified
IBS with constipation in women ≥18 y — 8 mcg twice daily
Mebeverine⚠ Unverified
IBS — adults: 135 mg three times daily
Plecanatide⚠ Unverified
IBS with constipation, adults — 3 mg once daily
Rifaximin⚠ Unverified
IBS-D — 550 mg three times daily for 14 days