Doz

Neurogenic detrusor overactivity

Neurogenic detrusor overactivity · ICD-10: N31.9

Symptoms

  • • Frequent urination in small amounts
  • • Incontinence and loss of bladder control
  • • Problems emptying the bladder fully
  • • Urinary retention or not sensing a full bladder (underactive bladder)

MedlinePlus · Symptoms

Drugs and regimens

Fesoterodine⚠ Unverified

Neurogenic detrusor overactivity, children ≥6 y and >25 kg — 4 mg once daily; >35 kg increase to 8 mg after one week

Mirabegron⚠ Unverified

Pediatric NDO (≥3 y, ≥35 kg) — 25 mg daily, up to 50 mg after 4–8 weeks

OnabotulinumtoxinA (Botox)⚠ Unverified

Adult neurogenic detrusor overactivity — 200 Units intradetrusor (30 sites)

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