Psoriasis and steroid-responsive dermatoses

Severe psoriasis, adults — 25–50 mg once daily with the main meal

Plaque psoriasis, PsA, Behçet’s — adult maintenance 30 mg twice daily (after 5-day titration)

Plaque psoriasis — thin layer twice daily

Moderate–severe plaque psoriasis — 400 mg every other week

Resistant dermatoses/psoriasis — twice daily, max 2 weeks

Severe psoriasis — start 2.5 mg/kg/day (1.25 mg/kg twice daily)

Adult plaque psoriasis — 50 mg twice weekly for 3 months, then once weekly

Moderate–severe plaque psoriasis (adults and children ≥6 y and ≥40 kg) — 100 mg at weeks 0, 4, then every 8 weeks

Chronic severe plaque psoriasis — 5 mg/kg per infusion

Plaque psoriasis, adults — 160 mg at week 0, then 80 mg every 2 weeks to week 12, then 80 mg every 4 weeks

Plaque psoriasis, children ≥6 y — every 4 weeks: 25–50 kg: 40 mg; >50 kg: 80 mg

Severe psoriasis — 10–25 mg once weekly

Plaque psoriasis or psoriatic arthritis, adults — 150 mg at weeks 0, 4, then every 12 weeks

Plaque psoriasis, children ≥6 y — <40 kg: 55 mg; ≥40 kg: 150 mg (weeks 0, 4, then every 12 weeks)

Adult plaque psoriasis — 300 mg (weeks 0–4, then every 4 weeks)

Plaque psoriasis — thin film of 0.05% cream (0.1% if tolerated) once nightly on lesions only

Moderate–severe plaque psoriasis, adults — 100 mg at weeks 0, 4, then every 12 weeks

Adult plaque psoriasis — ≤100 kg: 45 mg; >100 kg: 90 mg (weeks 0 and 4, then every 12 weeks)