Rheumatoid arthritis
Rheumatoid arthritis · ICD-10: M06.9
Symptoms
- • Joint pain and stiffness on both sides of the body
- • Morning stiffness lasting more than an hour
- • Warm, tender, swollen joints
- • Fatigue
- • Loss of range of motion and deformity over time
- • Dry eyes and mouth
Drugs and regimens
RA or PsA, adults (IV) — weeks 0, 2, 4 then every 4 weeks; <60 kg: 500, 60–100: 750, >100: 1000 mg
RA or PsA, adults (SC) — 125 mg once weekly
RA, PsA, ankylosing spondylitis — adult 40 mg every other week
Rheumatoid arthritis, adults — 100 mg SC daily
Rheumatoid arthritis — start about 1 mg/kg daily (50–100 mg)
Rheumatoid arthritis — 2 mg once daily
Rheumatoid arthritis — 100–200 mg twice daily
Loading (RA, PsA, axSpA, Crohn) — 400 mg (two 200 mg injections) at weeks 0, 2 and 4
Maintenance RA or PsA — 200 mg every 2 weeks (or 400 mg every 4 weeks)
Rheumatoid arthritis — start 2.5 mg/kg/day in two doses
Rheumatoid arthritis — 75 mg twice daily (150–200 mg/day)
RA, PsA, ankylosing spondylitis — 50 mg once WEEKLY
Rheumatoid arthritis — 60 mg once daily (max 90 mg)
RA (with methotrexate), PsA or AS, adults — 50 mg SC once a month
Rheumatoid arthritis — start 400–600 mg daily
RA, OA, ankylosing spondylitis — 25 mg two or three times daily
Rheumatoid arthritis — 3 mg/kg per infusion with methotrexate
Rheumatoid arthritis — loading 100 mg daily for 3 days (low hepatic/marrow risk)
Rheumatoid arthritis — maintenance 20 mg once daily (10 mg if not tolerated)
Rheumatoid arthritis — 7.5 mg once daily (up to 15 mg)
Rheumatoid arthritis — start 7.5 mg once weekly
Rheumatoid arthritis — two 1000 mg infusions 2 weeks apart (with methotrexate)
Rheumatoid arthritis — 2 g/day in 2 doses
Rheumatoid arthritis, adults (IV) — start 4 mg/kg every 4 weeks; increase to 8 mg/kg
Rheumatoid arthritis, adults (SC) — 162 mg every other week (<100 kg; may increase to weekly) or weekly (≥100 kg)
RA, PsA, AS — 5 mg twice daily (or XR 11 mg once daily)
Rheumatoid arthritis — 15 mg once daily