⚠️ Serious warning: Nothing on this website is approved by any physician. Doz is only a tool to help physicians and to search drugs easily. Taking medicines without medical supervision can be fatal.
Severe pain requiring an opioid
Severe pain requiring an opioid · ICD-10: R52
Drugs and regimens
Fentanyl transdermal patch⚠ Unverified
Severe persistent pain in opioid-TOLERANT patients — one patch every 72 h
Hydromorphone⚠ Unverified
Severe pain (opioid-naive) — 2–4 mg every 4–6 h as needed
Meperidine / pethidine (injection)⚠ Unverified
Pain — adult: 50–150 mg IM or SC every 3–4 h
Morphine (injection)⚠ Unverified
Severe pain — adult: 0.1–0.2 mg/kg IV every 4 h as needed
Morphine (oral, immediate-release)⚠ Unverified
Severe pain (opioid-naive) — 15–30 mg every 4 h as needed
Oxycodone⚠ Unverified
Severe pain (opioid-naive) — 5–15 mg every 4–6 h as needed
Tapentadol⚠ Unverified
Severe acute pain — 50–100 mg every 4–6 h as needed (adults and ≥6 y weighing ≥40 kg)