Spasticity (MS, spinal cord lesions)

Spasticity — ≥12 y: 5 mg three times daily, increase every 3 days

Paediatric upper-limb spasticity — 3–6 Units/kg total (max 200) divided among muscles

Paediatric lower-limb spasticity — 4–8 Units/kg total (max 300)

Adult spasticity — upper limb up to 400 Units; lower limb 300–400 Units divided among muscles

Spasticity — start 2 mg every 6–8 h as needed (max 3 doses)