Abiraterone acetate

🧮 Dose calculator

Prostate cancer · Regimen source: FDA Zytiga · 2.1

• • High-risk castration-sensitive: prednisone 5 mg once daily. No food 2 h before and 1 h after. With strong CYP3A4 inducers twice daily. FDA Zytiga · 2.2FDA Zytiga · 2FDA Zytiga · 2.5
• • With a GnRH analogue or after bilateral orchiectomy. FDA Zytiga · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Zytiga · 8.1

  “Based on findings from animal studies and the mechanism of action, ZYTIGA can cause fetal harm and potential loss of pregnancy.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Zytiga · 8.2

  “Risk Summary The safety and efficacy of ZYTIGA have not been established in females.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Zytiga · 8.4

  “Safety and effectiveness of ZYTIGA in pediatric patients have not been established.”

• 👴 Older adultsNo specific problem stated

  Label: no specific difference or dose adjustment stated for older adults. FDA Zytiga · 8.5

  “No overall differences in safety or effectiveness were observed between these elderly patients and younger patients.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Zytiga · 8.3

  “Contraception Males Based on findings in animal reproduction studies and its mechanism of action, advise males with female partners of reproductive potential to use effective contraception during treatment and for 3 weeks after the final dose of ZYTIGA [see Use in Specific Populations (8.1) ] .”