[{"data":1,"prerenderedAt":206},["ShallowReactive",2],{"drug-acyclovir-cream":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":35,"contraindications":61,"warnings":81,"renal":82,"monitoring":83,"interactions":84,"review":85,"examples":88,"atc":94,"iran":96,"links":148,"populations":167,"usApproval":201},"acyclovir-cream",1,{"fa":7,"en":8},"کرم آسیکلوویر","Acyclovir cream","dermatology",{"fa":11,"en":12},"ضدویروس موضعی","Topical antiviral",[14],{"name":15,"market":16},"Zovirax cream","US",[18,19,20,21],"zovirax cream","کرم زوویراکس","کرم تبخال","آسیکلوویر موضعی",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"cream-5","cream","topical","5% cream",{"amount":5,"unit":29,"perUnit":29},"application",[16],[32],{"source":33,"section":34},"fda-acyclovircream","3",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":29,"dose":47,"refs":49,"durationDays":52,"notes":54},"cold-sore","herpes-labialis",{"fa":40,"en":41},"تبخال — ۱۲ سال به بالا: ۵ بار در روز به مدت ۴ روز","Cold sores — ≥12 y: 5 times daily for 4 days",{"minAge":43},{"value":44,"unit":45},12,"year","fixed",{"perDose":5,"dosesPerDay":48},5,[50],{"source":33,"section":51},"2",{"min":53,"max":53},4,[55],{"text":56,"refs":59},{"fa":57,"en":58},"هر چه زودتر (در مرحله پیش‌علامت یا ظهور ضایعه) شروع شود.","Start as early as possible (prodrome or when lesions appear).",[60],{"source":33,"section":51},[62,71],{"id":63,"severity":64,"text":65,"refs":68},"ci","block",{"fa":66,"en":67},"حساسیت به آسیکلوویر، والاسیکلوویر یا اجزا.","Hypersensitivity to acyclovir, valacyclovir or any component.",[69],{"source":33,"section":70},"4",{"id":72,"severity":64,"rule":73,"text":75,"refs":78},"under-12",{"maxAge":74},{"value":44,"unit":45},{"fa":76,"en":77},"زیر ۱۲ سال ثابت نشده.","Not established under 12 years.",[79],{"source":33,"section":80},"8.4",[],[],[],[],{"status":86,"reviewer":87,"date":87},"unverified",null,[89],{"regimen":37,"formulation":24,"input":90,"expect":93},{"ageYears":91,"weightKg":92},25,60,{"perDay":48},[95],"D06BB03",{"status":97,"forms":98,"refs":143},"registered",[99,103,107,111,115,119,123,127,131,135,139],{"code":100,"en":101,"fa":102},"00020","ACICLOVIR 3% 3G OINT OPH","پماد چشمی آسیکلوویر ۳ درصد ۳ گرم",{"code":104,"en":105,"fa":106},"00023","ACICLOVIR 400MG TAB","قرص آسیکلوویر ۴۰۰ میلی‌گرم",{"code":108,"en":109,"fa":110},"00024","ACICLOVIR 5% 10G CREAM","کرم آسیکلوویر ۵ درصد ۱۰ گرم",{"code":112,"en":113,"fa":114},"12401","ACICLOVIR 800MG TAB","قرص آسیکلوویر ۸۰۰ میلی‌گرم",{"code":116,"en":117,"fa":118},"00022","ACICLOVIR SODIUM 250MG VIAL","ویال آسیکلوویر سدیم ۲۵۰ میلی‌گرم",{"code":120,"en":121,"fa":122},"02366","ACICLOVIR SODIUM 500MG VIAL","ویال آسیکلوویر سدیم ۵۰۰ میلی‌گرم",{"code":124,"en":125,"fa":126},"05981","IMMUNOVIR 500MG TAB","قرص ایممونوویر ۵۰۰ میلی‌گرم",{"code":128,"en":129,"fa":130},"00021","ACICLOVIR 200MG TAB","قرص آسیکلوویر ۲۰۰ میلی‌گرم",{"code":132,"en":133,"fa":134},"53200","ACICLOVIR 200 mg\u002F5mL 120 ML SUSPENSION","آسیکلوویر ۲۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۲۰ میلی‌لیتر",{"code":136,"en":137,"fa":138},"52881","ACICLOVIR CREAM TOPICAL 5 % 15 g","کرم آسیکلوویر ۵ درصد ۱۵ گرم",{"code":140,"en":141,"fa":142},"53098","ACICLOVIR SUSPENSION ORAL 200 mg\u002F5mL 120 mL","سوسپانسیون خوراکی آسیکلوویر ۲۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۲۰ میلی‌لیتر",[144],{"source":145,"section":146,"url":147},"darooyab-generic","G-1159\u002FAciclovir","https:\u002F\u002Fwww.darooyab.ir\u002FG-1159\u002FAciclovir",[149,153,157,161,164],{"kind":150,"url":151,"label":152},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=212361","ANDA212361",{"kind":154,"url":155,"label":156},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=878615c2-09ea-44ce-8c30-7a7f16acb20c","FDA Acyclovir cream",{"kind":158,"url":159,"label":160},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa606001.html","Acyclovir Topical",{"kind":162,"url":163,"label":95},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=D06BB03",{"kind":165,"url":147,"label":166},"darooyab","Aciclovir",{"pregnancy":168,"lactation":177,"pediatric":185,"geriatric":193},{"level":169,"text":170,"quote":173,"refs":174},"ok",{"fa":171,"en":172},"برچسب: جذب سیستمیک ناچیز؛ مواجهه جنین انتظار نمی‌رود.","Label: minimal systemic absorption; fetal exposure not expected.","Risk Summary Acyclovir is minimally absorbed systemically following topical route of administration, and maternal use is not expected to result in fetal exposure to the acyclovir cream [see Clinical Pharmacology ( 12.3 )] .",[175],{"source":33,"section":176},"8.1",{"level":169,"text":178,"quote":181,"refs":182},{"fa":179,"en":180},"برچسب: مواجهه شیرخوار انتظار نمی‌رود.","Label: infant exposure not expected.","Risk Summary Acyclovir is minimally absorbed systemically following topical route of administration, and breastfeeding is not expected to result in exposure of the child to acyclovir cream [see Clinical Pharmacology ( 12.3 )] .",[183],{"source":33,"section":184},"8.2",{"level":186,"text":187,"quote":190,"refs":191},"caution",{"fa":188,"en":189},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness in pediatric patients less than 12 years of age have not been established.",[192],{"source":33,"section":80},{"level":186,"text":194,"quote":197,"refs":198},{"fa":195,"en":196},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of acyclovir cream did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.",[199],{"source":33,"section":200},"8.5",{"kind":202,"refs":203,"id":152},"ANDA",[204],{"source":33,"section":205},"SPL approval \u002F marketing category",1792444704096]