Alendronate

آلندرونات

⚠ Unverified

🦴 Musculo-Skeletal SystemBisphosphonate

Market / country: 🇺🇸 USA

Fosamax (US)

🧮 Dose calculator

Osteoporosis / calcium and vitamin D deficiency · Regimen source: FDA Alendronate · 2.1

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🛡️ Safety & information

Contraindications

  • ⛔ Oesophageal abnormalities delaying emptying (stricture, achalasia); inability to stand or sit upright for 30 min; hypocalcaemia; hypersensitivity. FDA Alendronate · 4

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Alendronate · 8.1

    “Discontinue alendronate sodium when pregnancy is recognized.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Alendronate · 8.2

    “The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for alendronate sodium and any potential adverse effects on the breastfed child from alendronate sodium or from the underlying maternal condition.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Alendronate · 8.4

    “Alendronate sodium is not indicated for use in pediatric patients.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Alendronate · 8.5

    “Of the patients receiving alendronate sodium in the Fracture Intervention Trial (FIT), 71% (n=2302) were greater than or equal to 65 years of age and 17% (n=550) were greater than or equal to 75 years of age.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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