Alendronate
آلندرونات
🦴 Musculo-Skeletal SystemBisphosphonate
Market / country: 🇺🇸 USA
Fosamax (US)
🧮 Dose calculator
Osteoporosis / calcium and vitamin D deficiency · Regimen source: FDA Alendronate · 2.1
- • Once weekly (or 10 mg daily). Morning, fasting, full glass of water; stay upright and do not eat for 30 min. FDA Alendronate · 2.1FDA Alendronate · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Oesophageal abnormalities delaying emptying (stricture, achalasia); inability to stand or sit upright for 30 min; hypocalcaemia; hypersensitivity. FDA Alendronate · 4
Formulations
- 10 mg tablet — tablet 🇺🇸 USA FDA Alendronate · 3
- 35 mg tablet — tablet 🇺🇸 USA FDA Alendronate · 3
- 70 mg tablet — tablet 🇺🇸 USA FDA Alendronate · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Alendronate · 8.1
“Discontinue alendronate sodium when pregnancy is recognized.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Alendronate · 8.2
“The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for alendronate sodium and any potential adverse effects on the breastfed child from alendronate sodium or from the underlying maternal condition.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Alendronate · 8.4
“Alendronate sodium is not indicated for use in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Alendronate · 8.5
“Of the patients receiving alendronate sodium in the Fracture Intervention Trial (FIT), 71% (n=2302) were greater than or equal to 65 years of age and 17% (n=550) were greater than or equal to 75 years of age.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA090124
- DailyMed (FDA label)FDA Alendronate
- MedlinePlus (NIH)Alendronate
- WHO ATC/DDDM05BA04
- Darooyab (Iran)Alendronate
🇮🇷 Registered in Iran Darooyab · G-1427/Alendronate
Dosage forms with Iranian generic codes, per Darooyab.
- 01842 · ALENDRONATE SODIUM 10MG TAB · قرص آلندرونات سدیم ۱۰ میلیگرم
- 02405 · ALENDRONATE SODIUM 35MG TAB · قرص آلندرونات سدیم ۳۵ میلیگرم
- 02406 · ALENDRONATE SODIUM 70MG TAB · قرص آلندرونات سدیم ۷۰ میلیگرم
- 53192 · ALENDRONATE SODIUM 70MG EFF TAB · قرص جوشان آلندرونات سدیم ۷۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Alendronate · 3FDA Alendronate · 2.1FDA Alendronate · 2FDA Alendronate · 2.2FDA Alendronate · 2.4FDA Alendronate · 2.5FDA Alendronate · 4FDA Alendronate · 8.1FDA Alendronate · 8.2FDA Alendronate · 8.4FDA Alendronate · 8.5FDA Alendronate · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1427/Alendronate
- Clinical review⚠ Unverified