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Once in the morning or two equal doses. Do not open capsules.",[112,113],{"source":34,"section":101},{"source":34,"section":114},"2.2",{"id":116,"disease":87,"label":117,"population":120,"type":96,"unit":29,"dose":122,"refs":124,"limits":126},"lt70-target",{"fa":118,"en":119},"ADHD — کودکان زیر ۷۰ kg: دوز هدف ۱٫۲ mg\u002Fkg\u002Fday","ADHD — children \u003C70 kg: target 1.2 mg\u002Fkg\u002Fday",{"minAge":121,"maxWeightKg":95},{"value":93,"unit":94},{"perKgPerDay":123,"dividedDoses":5},1.2,[125],{"source":34,"section":101},{"maxPerKgPerDay":103,"maxPerDay":80,"refs":127},[128],{"source":34,"section":101},{"id":130,"disease":87,"label":131,"population":134,"type":136,"unit":29,"dose":137,"refs":140},"ge70",{"fa":132,"en":133},"ADHD — ۷۰ kg به بالا و بزرگسال: شروع ۴۰ mg، هدف ۸۰","ADHD — ≥70 kg and adults: start 40 mg, target 80",{"minWeightKg":135},70,"titration",{"dividedDoses":5,"titration":138},{"start":56,"increment":56,"incrementEveryDays":139,"targetMin":72,"targetMax":72,"max":80},3,[141],{"source":34,"section":101},[143],{"id":144,"severity":145,"text":146,"refs":149},"ci","block",{"fa":147,"en":148},"MAOI یا تا ۱۴ روز پس از قطع؛ گلوکوم زاویه بسته؛ حساسیت.","MAOI within 14 days; narrow-angle glaucoma; hypersensitivity.",[150],{"source":34,"section":151},"4",[153],{"text":154,"refs":157},{"fa":155,"en":156},"هشدار جعبه‌ای: افکار و رفتار خودکشی در کودکان ۶ سال به بالا؛ پایش دقیق. پیش از شروع، سابقه دوقطبی بررسی شود.","Boxed warning: suicidal thoughts and behaviors in pediatric patients ≥6 years; monitor closely. Screen for bipolar history before starting.",[158,160],{"source":34,"section":159},"WARNING: SUICIDAL THOUGHTS AND BEHAVIORS IN PEDIATRIC PATIENTS",{"source":34,"section":161},"2.1",[],[],[],{"status":166,"reviewer":167,"date":167},"unverified",null,[169,174,178],{"regimen":86,"formulation":23,"input":170,"expect":173},{"ageYears":171,"weightKg":172},7,20,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":116,"formulation":45,"input":175,"expect":176},{"ageYears":171,"weightKg":172},{"perDose":177,"tabletsPerDoseRounded":5},24,{"regimen":130,"formulation":53,"input":179,"expect":182},{"ageYears":180,"weightKg":181},30,75,{"perDose":56},[184],"N06BA09",{"status":186,"forms":187,"refs":228},"registered",[188,192,196,200,204,208,212,216,220,224],{"code":189,"en":190,"fa":191},"08394","ATOMOXETINE 10MG CAP","کپسول اتوموکستین ۱۰ میلی‌گرم",{"code":193,"en":194,"fa":195},"16730","ATOMOXETINE 10MG TAB","قرص اتوموکستین ۱۰ میلی‌گرم",{"code":197,"en":198,"fa":199},"06135","ATOMOXETINE 18MG CAP","کپسول اتوموکستین ۱۸ میلی‌گرم",{"code":201,"en":202,"fa":203},"16731","ATOMOXETINE 18MG TAB","قرص اتوموکستین ۱۸ میلی‌گرم",{"code":205,"en":206,"fa":207},"06136","ATOMOXETINE 25MG CAP","کپسول اتوموکستین ۲۵ میلی‌گرم",{"code":209,"en":210,"fa":211},"16732","ATOMOXETINE 25MG TAB","قرص اتوموکستین ۲۵ میلی‌گرم",{"code":213,"en":214,"fa":215},"06134","ATOMOXETINE 40MG CAP","کپسول اتوموکستین ۴۰ میلی‌گرم",{"code":217,"en":218,"fa":219},"17843","ATOMOXETINE 40MG TAB","قرص اتوموکستین ۴۰ میلی‌گرم",{"code":221,"en":222,"fa":223},"07287","ATOMOXETINE 60MG CAP","کپسول اتوموکستین ۶۰ میلی‌گرم",{"code":225,"en":226,"fa":227},"17844","ATOMOXETINE 60MG TAB","قرص اتوموکستین ۶۰ میلی‌گرم",[229],{"source":230,"section":231,"url":232},"darooyab-generic","G-3367\u002FAtomoxetine","https:\u002F\u002Fwww.darooyab.ir\u002FG-3367\u002FAtomoxetine",[234,238,242,245,248],{"kind":235,"url":236,"label":237},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=079019","ANDA079019",{"kind":239,"url":240,"label":241},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=0ab8d905-e890-4e91-a730-3e5d12f5c23f","FDA Atomoxetine",{"kind":243,"url":244,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa603013.html",{"kind":246,"url":247,"label":184},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N06BA09",{"kind":249,"url":232,"label":8},"darooyab",{"pregnancy":251,"lactation":260,"pediatric":268,"geriatric":277},{"level":252,"text":253,"quote":256,"refs":257},"caution",{"fa":254,"en":255},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Available published studies with atomoxetine use in pregnant women are insufficient to establish a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.",[258],{"source":34,"section":259},"8.1",{"level":252,"text":261,"quote":264,"refs":265},{"fa":262,"en":263},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no data on the presence of atomoxetine or its metabolite in human milk, the effects on the breastfed child, or the effects on milk production.",[266],{"source":34,"section":267},"8.2",{"level":269,"text":270,"quote":273,"refs":274},"avoid",{"fa":271,"en":272},"هشدار جعبه‌ای برچسب درباره کودکان.","Boxed warning in the label about children.","• All atomoxetine-treated pediatric patients 6 years of age or older should be monitored and observed closely for suicidal thoughts and behavior, clinical worsening, or unusual changes in behavior, especially during the initial months of therapy or at times of dosage changes.",[275],{"source":34,"section":276},"Boxed Warning",{"level":252,"text":278,"quote":281,"refs":282},{"fa":279,"en":280},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","The safety, efficacy and pharmacokinetics of atomoxetine in geriatric patients have not been evaluated.",[283],{"source":34,"section":284},"8.5",{"kind":286,"refs":287,"id":237},"ANDA",[288],{"source":34,"section":289},"SPL approval \u002F marketing category",1792444714598]