[{"data":1,"prerenderedAt":161},["ShallowReactive",2],{"drug-benzonatate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":44,"contraindications":72,"warnings":92,"renal":93,"monitoring":94,"interactions":95,"review":96,"examples":99,"atc":105,"iran":107,"links":114,"populations":131,"usApproval":156},"benzonatate",1,{"fa":7,"en":8},"بنزوناتات","Benzonatate","respiratory",{"fa":11,"en":12},"ضدسرفه غیرمخدر","Non-opioid antitussive",[14],{"name":15,"market":16},"Tessalon","US",[18,19,7,20],"tessalon","تسالون","پرل سرفه",[22,36],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"cap-100","capsule","oral","100 mg capsule",{"amount":28,"unit":29,"perUnit":24,"scored":30},100,"mg",false,[16],[33],{"source":34,"section":35},"fda-benzonatate","How Supplied",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"cap-200","200 mg capsule",{"amount":40,"unit":29,"perUnit":24,"scored":30},200,[16],[43],{"source":34,"section":35},[45],{"id":46,"disease":46,"label":47,"population":50,"type":54,"unit":29,"dose":55,"refs":57,"limits":60,"notes":64},"cough",{"fa":48,"en":49},"سرفه — بالای ۱۰ سال: ۱۰۰ یا ۲۰۰ mg سه بار در روز","Cough — >10 y: 100 or 200 mg three times daily",{"minAge":51},{"value":52,"unit":53},10,"year","fixed",{"perDose":28,"perDoseMax":40,"dosesPerDay":56},3,[58],{"source":34,"section":59},"Dosage and Administration",{"maxPerDay":61,"refs":62},600,[63],{"source":34,"section":59},[65],{"text":66,"refs":69},{"fa":67,"en":68},"کپسول کامل بلعیده شود: مکیدن یا جویدن آن با واکنش‌های شدید (برونکواسپاسم، لارنگواسپاسم، کلاپس قلبی‌عروقی) همراه بوده است.","Swallow whole: sucking or chewing the capsule has been linked to severe reactions (bronchospasm, laryngospasm, cardiovascular collapse).",[70],{"source":34,"section":71},"Warnings, Hypersensitivity",[73,82],{"id":74,"severity":75,"text":76,"refs":79},"ci","block",{"fa":77,"en":78},"حساسیت به بنزوناتات یا ترکیبات مشابه.","Hypersensitivity to benzonatate or related compounds.",[80],{"source":34,"section":81},"Contraindications",{"id":83,"severity":75,"rule":84,"text":86,"refs":89},"under-10",{"maxAge":85},{"value":52,"unit":53},{"fa":87,"en":88},"زیر ۱۰ سال ثابت نشده؛ بلع تصادفی در کودکان کشنده بوده است.","Not established under 10; accidental ingestion has killed children.",[90],{"source":34,"section":91},"Pediatric Use",[],[],[],[],{"status":97,"reviewer":98,"date":98},"unverified",null,[100],{"regimen":46,"formulation":23,"input":101,"expect":104},{"ageYears":102,"weightKg":103},30,70,{"perDose":28,"upperPerDose":40},[106],"R05DB01",{"status":108,"refs":109},"not-found",[110],{"source":111,"section":112,"url":113},"darooyab-generic","G-2139\u002FBenzonatate","https:\u002F\u002Fwww.darooyab.ir\u002FG-2139\u002FBenzonatate",[115,119,123,126,129],{"kind":116,"url":117,"label":118},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=202765","ANDA202765",{"kind":120,"url":121,"label":122},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=acf1f48c-15a1-431d-ab80-19587a7008ba","FDA Benzonatate",{"kind":124,"url":125,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682640.html",{"kind":127,"url":128,"label":106},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R05DB01",{"kind":130,"url":113,"label":8},"darooyab",{"pregnancy":132,"lactation":141,"pediatric":149},{"level":133,"text":134,"quote":137,"refs":138},"caution",{"fa":135,"en":136},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Animal reproduction studies have not been conducted with Benzonatate Capsules.",[139],{"source":34,"section":140},"Pregnancy Category C",{"level":133,"text":142,"quote":145,"refs":146},{"fa":143,"en":144},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk caution should be exercised when Benzonatate Capsule is administered to a nursing woman.",[147],{"source":34,"section":148},"Nursing Mothers",{"level":133,"text":150,"quote":153,"refs":154},{"fa":151,"en":152},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness in children below the age of 10 have not been established.",[155],{"source":34,"section":91},{"kind":157,"refs":158,"id":118},"ANDA",[159],{"source":34,"section":160},"SPL approval \u002F marketing category",1792440741497]