[{"data":1,"prerenderedAt":161},["ShallowReactive",2],{"drug-buspirone":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":63,"warnings":73,"renal":74,"monitoring":75,"interactions":76,"review":77,"examples":80,"atc":87,"iran":89,"links":105,"populations":122,"usApproval":156},"buspirone",1,{"fa":7,"en":8},"بوسپیرون","Buspirone","nervous-system",{"fa":11,"en":12},"ضداضطراب غیربنزودیازپینی","Non-benzodiazepine anxiolytic",[14],{"name":15,"market":16},"Buspar","US",[18,19,7],"buspar","بوسپار",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-15","tablet","oral","15 mg tablet (scored)",{"amount":27,"unit":28,"perUnit":23,"scored":29},15,"mg",true,[16],[32],{"source":33,"section":34},"fda-buspirone","Patient instructions — breaking the 15 mg tablet",[36],{"id":37,"disease":37,"label":38,"population":41,"type":45,"unit":28,"dose":46,"refs":49,"limits":52,"notes":56},"anxiety",{"fa":39,"en":40},"اضطراب — بزرگسال: ۷٫۵ mg دو بار در روز","Anxiety — adults: 7.5 mg twice daily",{"minAge":42},{"value":43,"unit":44},18,"year","fixed",{"perDose":47,"dosesPerDay":48},7.5,2,[50],{"source":33,"section":51},"Dosage and Administration",{"maxPerDay":53,"refs":54},60,[55],{"source":33,"section":51},[57],{"text":58,"refs":61},{"fa":59,"en":60},"هر ۲ تا ۳ روز ۵ mg\u002Fday افزایش؛ معمولاً ۲۰ تا ۳۰ mg\u002Fday.","Increase 5 mg\u002Fday every 2–3 days; usually 20–30 mg\u002Fday.",[62],{"source":33,"section":51},[64],{"id":65,"severity":66,"text":67,"refs":70},"ci","block",{"fa":68,"en":69},"حساسیت؛ MAOI یا تا ۱۴ روز پس از قطع.","Hypersensitivity; MAOI within 14 days.",[71],{"source":33,"section":72},"Contraindications",[],[],[],[],{"status":78,"reviewer":79,"date":79},"unverified",null,[81],{"regimen":37,"formulation":22,"input":82,"expect":85},{"ageYears":83,"weightKg":84},30,70,{"perDose":47,"tabletsPerDoseRounded":86},0.5,[88],"N05BE01",{"status":90,"forms":91,"refs":100},"registered",[92,96],{"code":93,"en":94,"fa":95},"11020","BUSPIRONE 10MG TAB","قرص بوسپیرون ۱۰ میلی‌گرم",{"code":97,"en":98,"fa":99},"01888","BUSPIRONE 5MG TAB","قرص بوسپیرون ۵ میلی‌گرم",[101],{"source":102,"section":103,"url":104},"darooyab-generic","G-1238\u002FBuspirone","https:\u002F\u002Fwww.darooyab.ir\u002FG-1238\u002FBuspirone",[106,110,114,117,120],{"kind":107,"url":108,"label":109},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=202087","ANDA202087",{"kind":111,"url":112,"label":113},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=fdacb3d3-f574-431a-8324-2278edc16bce","FDA Buspirone",{"kind":115,"url":116,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa688005.html",{"kind":118,"url":119,"label":88},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N05BE01",{"kind":121,"url":104,"label":8},"darooyab",{"pregnancy":123,"lactation":132,"pediatric":140,"geriatric":148},{"level":124,"text":125,"quote":128,"refs":129},"caution",{"fa":126,"en":127},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Teratogenic Effects Pregnancy Category B: No fertility impairment or fetal damage was observed in reproduction studies performed in rats and rabbits at buspirone doses of approximately 30 times the maximum recommended human dose.",[130],{"source":33,"section":131},"Precautions\u002FWarnings – Pregnancy",{"level":124,"text":133,"quote":136,"refs":137},{"fa":134,"en":135},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","The extent of the excretion in human milk of buspirone or its metabolites is not known.",[138],{"source":33,"section":139},"Nursing Mothers",{"level":124,"text":141,"quote":144,"refs":145},{"fa":142,"en":143},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of buspirone were evaluated in two placebo-controlled 6-week trials involving a total of 559 pediatric patients (ranging from 6 to 17 years of age) with GAD.",[146],{"source":33,"section":147},"Pediatric Use",{"level":124,"text":149,"quote":152,"refs":153},{"fa":150,"en":151},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In one study of 6632 patients who received buspirone for the treatment of anxiety, 605 patients were ≥65 years old and 41 were ≥75 years old; the safety and efficacy profiles for these 605 elderly patients (mean age = 70.8 years) were similar to those in the younger population (mean age = 43.3 years).",[154],{"source":33,"section":155},"Precautions\u002FWarnings – Geriatric Use",{"kind":157,"refs":158,"id":109},"ANDA",[159],{"source":33,"section":160},"SPL approval \u002F marketing category",1792444714218]