Busulfan

🧮 Dose calculator

Chronic myeloid leukaemia (CML) · Regimen source: FDA Myleran · Dosage and Administration

• • WBC fall is dose-related; above 4 mg/day only if response is insufficient. Children: same weight-based dose. Weekly counts. FDA Myleran · Dosage and Administration

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Myleran · Pregnancy

  “Busulfan may cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Myleran · Lactation

  “Because of the potential for tumorigenicity shown for busulfan in animal and human studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Myleran · Pediatric Use

  “See INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION sections.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Myleran · Geriatric Use

  “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.