[{"data":1,"prerenderedAt":215},["ShallowReactive",2],{"drug-chlorphenamine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":23,"regimens":38,"contraindications":78,"warnings":97,"renal":105,"monitoring":106,"interactions":107,"review":108,"examples":110,"atc":128,"iran":130,"links":166,"populations":184},"chlorphenamine",1,{"fa":7,"en":8},"کلرفنیرامین","Chlorphenamine (chlorpheniramine)","respiratory",{"fa":11,"en":12},"آنتی‌هیستامین نسل اول","First-generation antihistamine",[14,17],{"name":15,"market":16},"Piriton","GB",{"name":18,"market":19},"Chlor-Trimeton","US",[21,7,22],"chlorpheniramine","piriton",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":33,"refs":34},"syr-2-5","syrup","oral","2 mg \u002F 5 mL syrup",{"amount":30,"unit":31,"perVolumeMl":32},2,"mg",5,[16],[35],{"source":36,"section":37},"uk-smpc-piriton","2",[39],{"id":40,"disease":41,"label":42,"population":45,"type":48,"unit":31,"dose":49,"refs":66,"notes":71},"allergy","allergic-conditions",{"fa":43,"en":44},"حالات آلرژیک و خارش آبله‌مرغان","Allergic conditions and chickenpox itch",{"minAge":46},{"value":5,"unit":47},"year","ageBand",{"intervalHours":50,"bands":51},4,[52,55,59,63],{"minAge":53,"maxAge":54,"perDose":5,"dosesPerDay":30},{"value":5,"unit":47},{"value":30,"unit":47},{"minAge":56,"maxAge":57,"perDose":5,"dosesPerDay":58},{"value":30,"unit":47},{"value":58,"unit":47},6,{"minAge":60,"maxAge":61,"perDose":30,"dosesPerDay":58},{"value":58,"unit":47},{"value":62,"unit":47},12,{"minAge":64,"maxAge":65,"perDose":50,"dosesPerDay":58},{"value":62,"unit":47},null,[67,69],{"source":36,"section":68},"4.2",{"source":36,"section":70},"4.1",[72],{"text":73,"refs":76},{"fa":74,"en":75},"هر ۴ تا ۶ ساعت (۱ تا ۲ سال: دو بار در روز). حداکثر روزانه: ۱–۲ سال ۲ mg؛ ۲–۶ سال ۶ mg؛ ۶–۱۲ سال ۱۲ mg؛ ۱۲ سال به بالا ۲۴ mg. بیش از ۲ هفته بدون مشورت ادامه نیابد. زیر ۱ سال توصیه نمی‌شود.","Every 4–6 h (1–2 years: twice daily). Daily max: 1–2 y 2 mg; 2–6 y 6 mg; 6–12 y 12 mg; ≥12 y 24 mg. Not continuously >2 weeks without advice. Not recommended under 1 year.",[77],{"source":36,"section":68},[79,89],{"id":80,"severity":81,"rule":82,"text":84,"refs":87},"under-1","block",{"maxAge":83},{"value":5,"unit":47},{"fa":85,"en":86},"زیر ۱ سال توصیه نمی‌شود.","Not recommended for children below 1 year.",[88],{"source":36,"section":68},{"id":90,"severity":81,"text":91,"refs":94},"maoi",{"fa":92,"en":93},"مصرف MAOI در ۱۴ روز گذشته؛ حساسیت به آنتی‌هیستامین‌ها.","MAOI treatment within the last 14 days; hypersensitivity to antihistamines.",[95],{"source":36,"section":96},"4.3",[98],{"text":99,"refs":102},{"fa":100,"en":101},"احتیاط در صرع، گلوکوم، هیپرتروفی پروستات، آسم\u002Fبرونشیت، نارسایی کبد یا کلیه؛ تحریک متناقض در کودکان.","Caution in epilepsy, glaucoma, prostatic hypertrophy, asthma\u002Fbronchitis, hepatic or renal impairment; paradoxical excitation in children.",[103],{"source":36,"section":104},"4.4",[],[],[],{"status":109,"reviewer":65,"date":65},"unverified",[111,117,122],{"regimen":40,"formulation":25,"input":112,"expect":115},{"ageMonths":113,"weightKg":114},18,11,{"perDose":5,"mlPerDose":116,"perDay":30},2.5,{"regimen":40,"formulation":25,"input":118,"expect":121},{"ageYears":119,"weightKg":120},8,25,{"perDose":30,"mlPerDose":32,"perDay":62},{"regimen":40,"formulation":25,"input":123,"expect":126},{"ageYears":124,"weightKg":125},30,70,{"perDose":50,"perDay":127},24,[129],"R06AB04",{"status":131,"forms":132,"refs":161},"registered",[133,137,141,145,149,153,157],{"code":134,"en":135,"fa":136},"00275","CHLORPHENIRAMINE MALEATE 10MG\u002F1ML AMP","آمپول کلرفنیرامین مالئات ۱۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":138,"en":139,"fa":140},"02014","CHLORPHENIRAMINE MALEATE 2MG\u002F5ML 60ML SYRUP","شربت کلرفنیرامین مالئات ۲ میلی‌گرم \u002F ۵ میلی‌لیتر ۶۰ میلی‌لیتر",{"code":142,"en":143,"fa":144},"00276","CHLORPHENIRAMINE MALEATE 4MG TAB","قرص کلرفنیرامین مالئات ۴ میلی‌گرم",{"code":146,"en":147,"fa":148},"01431","CHLORPHENIRAMINE MALEATE SR 8MG TAB","قرص آهسته‌رهش کلرفنیرامین مالئات ۸ میلی‌گرم",{"code":150,"en":151,"fa":152},"00402","DEXCHLORPHENIRAMINE MALEATE 2MG TAB","قرص دکسکلرفنیرامین مالئات ۲ میلی‌گرم",{"code":154,"en":155,"fa":156},"00401","DEXCHLORPHENIRAMINE MALEATE 2MG\u002F5ML SYRUP","شربت دکسکلرفنیرامین مالئات ۲ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":158,"en":159,"fa":160},"01459","DEXCHLORPHENIRAMINE MALEATE SR 6MG TAB","قرص آهسته‌رهش دکسکلرفنیرامین مالئات ۶ میلی‌گرم",[162],{"source":163,"section":164,"url":165},"darooyab-generic","G-779\u002FChlorpheniramine-Maleate","https:\u002F\u002Fwww.darooyab.ir\u002FG-779\u002FChlorpheniramine-Maleate",[167,171,174,177,180],{"kind":168,"url":169,"label":170},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682543.html","Chlorpheniramine",{"kind":168,"url":172,"label":173},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682492.html","Dextromethorphan",{"kind":175,"url":176,"label":129},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R06AB04",{"kind":178,"url":165,"label":179},"darooyab","Chlorpheniramine-Maleate",{"kind":181,"url":182,"label":183},"emc","https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F3928\u002Fsmpc","UK SmPC Piriton",{"pregnancy":185,"lactation":194,"pediatric":201,"geriatric":208},{"level":186,"text":187,"quote":190,"refs":191},"caution",{"fa":188,"en":189},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","There are no adequate data from the use of chlorphenamine in pregnant women.",[192],{"source":36,"section":193},"4.6",{"level":186,"text":195,"quote":198,"refs":199},{"fa":196,"en":197},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Chlorphenamine maleate and other antihistamines may inhibit lactation and may be secreted in breast milk.",[200],{"source":36,"section":193},{"level":186,"text":202,"quote":205,"refs":206},{"fa":203,"en":204},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Children aged 6 - 12 years : 5ml (2mg) every 4 to 6 hourly.",[207],{"source":36,"section":68},{"level":186,"text":209,"quote":212,"refs":213},{"fa":210,"en":211},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Elderly : The elderly are more likely to experience neurological anticholinergic effects.",[214],{"source":36,"section":68},1792191880297]