[{"data":1,"prerenderedAt":196},["ShallowReactive",2],{"drug-chlorthalidone":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":19,"regimens":42,"contraindications":101,"warnings":111,"renal":112,"monitoring":113,"interactions":114,"review":115,"examples":118,"atc":128,"iran":130,"links":146,"populations":164,"usApproval":191},"chlorthalidone",1,{"fa":7,"en":8},"کلرتالیدون","Chlorthalidone","cardiovascular",{"fa":11,"en":12},"دیورتیک شبه‌تیازید","Thiazide-like diuretic",[14],{"name":15,"market":16},"Thalitone","US",[18,7],"thalitone",[20,34],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":29,"refs":30},"tab-25","tablet","oral","25 mg tablet",{"amount":26,"unit":27,"perUnit":22,"scored":28},25,"mg",false,[16],[31],{"source":32,"section":33},"fda-chlorthalidone","How Supplied",{"id":35,"form":22,"route":23,"label":36,"concentration":37,"markets":39,"refs":40},"tab-50","50 mg tablet",{"amount":38,"unit":27,"perUnit":22,"scored":28},50,[16],[41],{"source":32,"section":33},[43,69,86],{"id":44,"disease":45,"label":46,"population":49,"type":53,"unit":27,"dose":54,"refs":55,"limits":58,"notes":62},"htn","hypertension",{"fa":47,"en":48},"فشار خون — ۲۵ mg یک بار در روز","Hypertension — 25 mg once daily",{"minAge":50},{"value":51,"unit":52},18,"year","fixed",{"perDose":26,"dosesPerDay":5},[56],{"source":32,"section":57},"Dosage and Administration",{"maxPerDay":59,"refs":60},100,[61],{"source":32,"section":57},[63],{"text":64,"refs":67},{"fa":65,"en":66},"در صورت نیاز ۵۰ و سپس ۱۰۰ mg؛ بالای ۱۰۰ معمولاً اثر بیشتری ندارد.","If needed 50 then 100 mg; above 100 usually no more effect.",[68],{"source":32,"section":57},{"id":70,"disease":70,"label":71,"population":74,"type":53,"unit":27,"dose":76,"refs":77,"notes":79},"edema",{"fa":72,"en":73},"ادم — ۵۰ تا ۱۰۰ mg روزانه (یا ۱۰۰ mg یک روز در میان)","Edema — 50–100 mg daily (or 100 mg on alternate days)",{"minAge":75},{"value":51,"unit":52},{"perDose":38,"perDoseMax":59,"dosesPerDay":5},[78],{"source":32,"section":57},[80],{"text":81,"refs":84},{"fa":82,"en":83},"برخی تا ۱۵۰ تا ۲۰۰ mg.","Some need 150–200 mg.",[85],{"source":32,"section":57},{"id":87,"disease":45,"label":88,"population":91,"type":93,"unit":27,"dose":94,"refs":98},"peds",{"fa":89,"en":90},"زیر ۱۸ سال","Under 18 years",{"maxAge":92},{"value":51,"unit":52},"notCalculated",{"reason":95},{"fa":96,"en":97},"بی‌خطری و اثربخشی در کودکان ثابت نشده است.","Safety and effectiveness in children not established.",[99],{"source":32,"section":100},"Pediatric Use",[102],{"id":103,"severity":104,"text":105,"refs":108},"ci","block",{"fa":106,"en":107},"آنوری؛ حساسیت به کلرتالیدون یا سولفونامیدها.","Anuria; hypersensitivity to chlorthalidone or sulfonamides.",[109],{"source":32,"section":110},"Contraindications",[],[],[],[],{"status":116,"reviewer":117,"date":117},"unverified",null,[119,124],{"regimen":44,"formulation":21,"input":120,"expect":123},{"ageYears":121,"weightKg":122},55,80,{"perDose":26},{"regimen":70,"formulation":35,"input":125,"expect":127},{"ageYears":126,"weightKg":122},60,{"perDose":38,"upperPerDose":59},[129],"C03BA04",{"status":131,"forms":132,"refs":141},"registered",[133,137],{"code":134,"en":135,"fa":136},"00280","CHLORTHALIDONE 100MG TAB","قرص کلرتالیدون ۱۰۰ میلی‌گرم",{"code":138,"en":139,"fa":140},"53563","CHLORTHALIDONE 50MG TAB","قرص کلرتالیدون ۵۰ میلی‌گرم",[142],{"source":143,"section":144,"url":145},"darooyab-generic","G-1592\u002FChlortalidone","https:\u002F\u002Fwww.darooyab.ir\u002FG-1592\u002FChlortalidone",[147,151,155,158,161],{"kind":148,"url":149,"label":150},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=209162","ANDA209162",{"kind":152,"url":153,"label":154},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=a6fa12f0-a2bc-456a-9f25-f69bb31fdb60","FDA Chlorthalidone",{"kind":156,"url":157,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682342.html",{"kind":159,"url":160,"label":129},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C03BA04",{"kind":162,"url":145,"label":163},"darooyab","Chlortalidone",{"pregnancy":165,"lactation":174,"pediatric":183},{"level":166,"text":167,"quote":170,"refs":171},"caution",{"fa":168,"en":169},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Pregnancy Category B Reproduction studies have been performed in the rat and the rabbit at doses up to 420 times the human dose and have revealed no evidence of harm to the fetus due to chlorthalidone.",[172],{"source":32,"section":173},"Pregnancy",{"level":175,"text":176,"quote":179,"refs":180},"avoid",{"fa":177,"en":178},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions in nursing infants from chlorthalidone, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[181],{"source":32,"section":182},"Nursing Mothers",{"level":184,"text":185,"quote":188,"refs":189},"not-established",{"fa":186,"en":187},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in children have not been established.",[190],{"source":32,"section":100},{"kind":192,"refs":193,"id":150},"ANDA",[194],{"source":32,"section":195},"SPL approval \u002F marketing category",1792440727591]