[{"data":1,"prerenderedAt":209},["ShallowReactive",2],{"drug-chorionic-gonadotropin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":19,"formulations":26,"regimens":41,"contraindications":97,"warnings":107,"renal":116,"monitoring":117,"interactions":118,"review":119,"examples":122,"atc":128,"iran":130,"links":162,"populations":177,"usApproval":204},"chorionic-gonadotropin",1,{"fa":7,"en":8},"گنادوتروپین جفتی انسانی (hCG)","Chorionic gonadotropin (hCG)","genitourinary-sex-hormones",{"fa":11,"en":12},"گنادوتروپین","Gonadotropin",[14,17],{"name":15,"market":16},"Novarel","US",{"name":18,"market":16},"Pregnyl",[20,21,22,23,24,25],"hcg","novarel","pregnyl","پرگنیل","اچ سی جی","گنادوتروپین کوریونیک",[27],{"id":28,"form":29,"route":30,"label":31,"concentration":32,"markets":36,"refs":37},"vial-10000","powder-for-injection","im","10,000 USP units vial (also 5,000) — IM only",{"amount":33,"unit":34,"perUnit":35},10000,"unit","vial",[16],[38],{"source":39,"section":40},"fda-novarel","How Supplied",[42,67,83],{"id":43,"disease":44,"label":45,"population":48,"type":52,"unit":34,"dose":53,"refs":55,"durationDays":58,"notes":59},"ovul","female-infertility",{"fa":46,"en":47},"القای تخمک‌گذاری پس از منوتروپین‌ها — ۵۰۰۰ تا ۱۰۰۰۰ واحد عضلانی یک روز پس از آخرین دوز منوتروپین","Ovulation induction after menotropins — 5,000–10,000 units IM one day after the last menotropins dose",{"minAge":49},{"value":50,"unit":51},18,"year","fixed",{"perDose":54,"perDoseMax":33,"dosesPerDay":5},5000,[56],{"source":39,"section":57},"Dosage and Administration",{"min":5,"max":5},[60],{"text":61,"refs":64},{"fa":62,"en":63},"فقط توسط پزشک باتجربه در ناباروری. در خطر OHSS در پایش تخمدان، hCG داده نشود.","Only by physicians experienced in infertility. Withhold hCG if ovarian monitoring suggests OHSS risk.",[65],{"source":39,"section":66},"Warnings",{"id":68,"disease":69,"label":70,"population":73,"type":75,"unit":76,"dose":77,"refs":81},"crypt","cryptorchidism",{"fa":71,"en":72},"بیضه نزول‌نکرده پیش از بلوغ (بدون انسداد آناتومیک) — رژیم‌های عضلانی برچسب","Prepubertal cryptorchidism (not due to anatomical obstruction) — labelled IM regimens",{"maxAge":74},{"value":50,"unit":51},"notCalculated","mg",{"reason":78},{"fa":79,"en":80},"یکی از رژیم‌ها: ۴۰۰۰ واحد سه بار در هفته ۳ هفته؛ ۵۰۰۰ واحد یک روز در میان ۴ تزریق؛ ۱۵ تزریق ۵۰۰ تا ۱۰۰۰ واحد طی ۶ هفته؛ ۵۰۰ واحد سه بار در هفته ۴ تا ۶ هفته.","One of: 4,000 units three times weekly for 3 weeks; 5,000 units every other day for 4 injections; 15 injections of 500–1,000 units over 6 weeks; 500 units three times weekly for 4–6 weeks.",[82],{"source":39,"section":57},{"id":84,"disease":85,"label":86,"population":89,"type":75,"unit":76,"dose":91,"refs":95},"hypogon","male-hypogonadism",{"fa":87,"en":88},"هیپوگنادیسم هیپوگنادوتروپیک مردان (موارد منتخب) — رژیم‌های عضلانی برچسب","Selected hypogonadotropic hypogonadism in males — labelled IM regimens",{"minAge":90},{"value":50,"unit":51},{"reason":92},{"fa":93,"en":94},"۵۰۰ تا ۱۰۰۰ واحد سه بار در هفته ۳ هفته، سپس همان دوز دو بار در هفته ۳ هفته؛ یا ۴۰۰۰ واحد سه بار در هفته ۶ تا ۹ ماه، سپس ۲۰۰۰ واحد سه بار در هفته ۳ ماه دیگر.","500–1,000 units three times weekly for 3 weeks, then twice weekly for 3 weeks; or 4,000 units three times weekly for 6–9 months, then 2,000 units three times weekly for 3 more months.",[96],{"source":39,"section":57},[98],{"id":99,"severity":100,"text":101,"refs":104},"ci","block",{"fa":102,"en":103},"بلوغ زودرس؛ سرطان پروستات یا سایر نئوپلاسم‌های وابسته به آندروژن؛ سابقه حساسیت به hCG.","Precocious puberty; prostatic carcinoma or other androgen-dependent neoplasm; prior allergic reaction to hCG.",[105],{"source":39,"section":106},"Contraindications",[108],{"text":109,"refs":112},{"fa":110,"en":111},"سندرم تحریک بیش از حد تخمدان (OHSS)؛ پارگی کیست تخمدان؛ بارداری چندقلو؛ ترومبوآمبولی. برای کاهش وزن مؤثر نیست.","Ovarian hyperstimulation syndrome; ovarian cyst rupture; multiple births; thromboembolism. Not effective for weight loss.",[113,114],{"source":39,"section":66},{"source":39,"section":115},"Indications and Usage",[],[],[],{"status":120,"reviewer":121,"date":121},"unverified",null,[123],{"regimen":43,"formulation":28,"input":124,"expect":127},{"ageYears":125,"weightKg":126},32,60,{"perDose":54,"upperPerDose":33},[129],"G03GA01",{"status":131,"forms":132,"refs":157},"registered",[133,137,141,145,149,153],{"code":134,"en":135,"fa":136},"11405","CHORIO GONADOTROPIN ALFA 250MCG\u002F0.5ML SOL FOR INJ","فرآورده تزریقی چوریو گنادوتروپین آلفا ۲۵۰ میکروگرم \u002F ۰٫۵ میلی‌لیتر",{"code":138,"en":139,"fa":140},"00284","CHORIONIC GONADOTROPHIN (HUMAN) 1500 U VIAL","ویال کوریونی گنادوتروپین (انسانی) ۱۵۰۰ واحد",{"code":142,"en":143,"fa":144},"08716","CHORIONIC GONADOTROPHIN (HUMAN) 2000IU VIAL","ویال کوریونی گنادوتروپین (انسانی) ۲۰۰۰ واحد بین‌المللی",{"code":146,"en":147,"fa":148},"07390","CHORIONIC GONADOTROPHIN (HUMAN) 2500IU VIAL","ویال کوریونی گنادوتروپین (انسانی) ۲۵۰۰ واحد بین‌المللی",{"code":150,"en":151,"fa":152},"00285","CHORIONIC GONADOTROPHIN (HUMAN) 500 U VIAL","ویال کوریونی گنادوتروپین (انسانی) ۵۰۰ واحد",{"code":154,"en":155,"fa":156},"00286","CHORIONIC GONADOTROPHIN (HUMAN) 5000 U VIAL","ویال کوریونی گنادوتروپین (انسانی) ۵۰۰۰ واحد",[158],{"source":159,"section":160,"url":161},"darooyab-generic","G-2689\u002FHuman-Chorionic-Gonadotrophin","https:\u002F\u002Fwww.darooyab.ir\u002FG-2689\u002FHuman-Chorionic-Gonadotrophin",[163,167,171,174],{"kind":164,"url":165,"label":166},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=017016","BLA017016",{"kind":168,"url":169,"label":170},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=ac6918ff-9dc3-40d9-8619-54b26e4bdfc8","FDA Novarel",{"kind":172,"url":173,"label":129},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G03GA01",{"kind":175,"url":161,"label":176},"darooyab","Human-Chorionic-Gonadotrophin",{"pregnancy":178,"lactation":187,"pediatric":196},{"level":179,"text":180,"quote":183,"refs":184},"contraindicated",{"fa":181,"en":182},"برچسب: در بارداری منع مصرف دارد.","Label: contraindicated in pregnancy.","HCG may cause fetal harm when administered to a pregnant woman.",[185],{"source":39,"section":186},"CONTRAINDICATIONS",{"level":188,"text":189,"quote":192,"refs":193},"caution",{"fa":190,"en":191},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when HCG is administered to a nursing woman.",[194],{"source":39,"section":195},"Nursing Mothers",{"level":188,"text":197,"quote":200,"refs":201},{"fa":198,"en":199},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness in children below the age of 4 have not been established.",[202],{"source":39,"section":203},"Pediatric Use",{"kind":205,"refs":206,"id":166},"BLA",[207],{"source":39,"section":208},"SPL approval \u002F marketing category",1792444704450]