[{"data":1,"prerenderedAt":311},["ShallowReactive",2],{"drug-clotrimazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":61,"contraindications":154,"warnings":164,"renal":165,"monitoring":166,"interactions":167,"review":168,"examples":171,"atc":195,"iran":197,"links":253,"populations":281,"usApproval":306},"clotrimazole",1,{"fa":7,"en":8},"کلوتریمازول","Clotrimazole","dermatology",{"fa":11,"en":12},"ضدقارچ آزول موضعی","Topical azole antifungal",[14],{"name":15,"market":16},"Canesten","GB",[18,19,7,20,21],"canesten","کانستن","کرم قارچ","شیاف قارچ واژن",[23,35,47],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"cream-1","cream","topical","1% cream",{"amount":5,"unit":29,"perUnit":29},"application",[16],[32],{"source":33,"section":34},"uk-smpc-canesten-cream","2",{"id":36,"form":37,"route":38,"label":39,"concentration":40,"markets":43,"refs":44},"pess-500","pessary","vaginal","500 mg vaginal pessary",{"amount":41,"unit":42,"perUnit":29},500,"mg",[16],[45],{"source":46,"section":34},"uk-smpc-canesten-pessary-500",{"id":48,"form":49,"route":50,"label":51,"concentration":52,"markets":55,"refs":57},"troche-10","lozenge","oral","10 mg lozenge (troche)",{"amount":53,"unit":42,"perUnit":54},10,"tablet",[56],"US",[58],{"source":59,"section":60},"fda-clotroche","How Supplied",[62,88,111,134],{"id":63,"disease":63,"label":64,"population":67,"type":68,"unit":29,"dose":69,"refs":71,"limits":74,"allowedFormulations":78,"notes":79},"tinea",{"fa":65,"en":66},"قارچ پوستی\u002Fکاندیدای پوستی — دو یا سه بار در روز","Fungal skin \u002F cutaneous candida — two or three times daily",{},"fixed",{"perDose":5,"dosesPerDay":70},2,[72],{"source":33,"section":73},"4.2",{"maxPerDay":75,"refs":76},3,[77],{"source":33,"section":73},[24],[80],{"text":81,"refs":84},{"fa":82,"en":83},"لایه نازک؛ نیم سانتی‌متر برای سطحی به اندازه کف دست. درماتوفیت حداقل ۱ ماه، کاندیدا حداقل ۲ هفته. برای ناخن یا پوست سر نیست.","Thin layer; ½ cm strip covers a hand-sized area. Dermatophytes at least 1 month; candida at least 2 weeks. Not for nail or scalp.",[85,86],{"source":33,"section":73},{"source":33,"section":87},"4.3",{"id":38,"disease":89,"label":90,"population":93,"type":68,"unit":42,"dose":97,"refs":98,"durationDays":100,"allowedFormulations":101,"notes":102},"vaginal-candidiasis",{"fa":91,"en":92},"کاندیدیاز واژن — بزرگسال: شیاف ۵۰۰ mg یک‌بار شب","Vaginal candidiasis — adults: one 500 mg pessary at night",{"minAge":94},{"value":95,"unit":96},18,"year",{"perDose":41,"dosesPerDay":5},[99],{"source":46,"section":73},{"min":5,"max":5},[36],[103],{"text":104,"refs":107},{"fa":105,"en":106},"با اپلیکاتور تا حد ممکن عمیق. در صورت نیاز یک نوبت دیگر. اولین بار یا بیش از ۲ بار در ۶ ماه: مشورت پزشک.","With the applicator as high as possible. A second treatment if needed. First episode or >2 in 6 months: see a doctor.",[108,109],{"source":46,"section":73},{"source":46,"section":110},"4.4",{"id":112,"disease":113,"label":114,"population":117,"type":68,"unit":42,"dose":119,"refs":121,"durationDays":124,"allowedFormulations":126,"notes":127},"thrush","oral-candidiasis",{"fa":115,"en":116},"برفک دهان — یک قرص مکیدنی ۵ بار در روز، ۱۴ روز (۳ سال به بالا)","Oral thrush — one lozenge 5 times daily, 14 days (≥3 y)",{"minAge":118},{"value":75,"unit":96},{"perDose":53,"dosesPerDay":120},5,[122],{"source":59,"section":123},"Dosage and Administration",{"min":125,"max":125},14,[48],[128],{"text":129,"refs":132},{"fa":130,"en":131},"آهسته در دهان حل شود؛ جویده یا بلعیده نشود.","Dissolve slowly in the mouth; do not chew or swallow whole.",[133],{"source":59,"section":123},{"id":135,"disease":113,"label":136,"population":139,"type":68,"unit":42,"dose":141,"refs":142,"allowedFormulations":144,"notes":145},"thrush-proph",{"fa":137,"en":138},"پیشگیری از برفک در نقص ایمنی (شیمی‌درمانی، پرتودرمانی، کورتون) — یک قرص ۳ بار در روز","Thrush prophylaxis in immunosuppression (chemo, radiotherapy, steroids) — one lozenge 3 times daily",{"minAge":140},{"value":95,"unit":96},{"perDose":53,"dosesPerDay":75},[143],{"source":59,"section":123},[48],[146],{"text":147,"refs":150},{"fa":148,"en":149},"در طول شیمی‌درمانی یا تا کاهش کورتون به دوز نگهدارنده. ایمنی پیشگیری در کودکان ثابت نشده.","For the duration of chemotherapy or until steroids are reduced to maintenance. Prophylactic safety not established in children.",[151,152],{"source":59,"section":123},{"source":59,"section":153},"Pediatric Use",[155],{"id":156,"severity":157,"text":158,"refs":161},"ci","block",{"fa":159,"en":160},"حساسیت به کلوتریمازول.","Hypersensitivity to clotrimazole.",[162,163],{"source":33,"section":87},{"source":46,"section":87},[],[],[],[],{"status":169,"reviewer":170,"date":170},"unverified",null,[172,177,182,186,191],{"regimen":63,"formulation":24,"input":173,"expect":176},{"ageYears":174,"weightKg":175},20,65,{"perDose":5,"perDay":70},{"regimen":38,"formulation":36,"input":178,"expect":181},{"ageYears":179,"weightKg":180},25,60,{"perDose":41},{"regimen":38,"formulation":24,"input":183,"expect":184},{"ageYears":179,"weightKg":180},{"status":185},"blocked",{"regimen":112,"formulation":48,"input":187,"expect":190},{"ageYears":188,"weightKg":189},30,70,{"perDose":53,"tabletsPerDoseRounded":5,"dosesPerDay":120},{"regimen":135,"formulation":48,"input":192,"expect":194},{"ageYears":193,"weightKg":189},50,{"perDose":53,"dosesPerDay":75},[196],"D01AC01",{"status":198,"forms":199,"refs":248},"registered",[200,204,208,212,216,220,224,228,232,236,240,244],{"code":201,"en":202,"fa":203},"00326","CLOTRIMAZOLE 1% 15G TOP CREAM","کرم کلوتریمازول ۱ درصد ۱۵ گرم",{"code":205,"en":206,"fa":207},"12859","CLOTRIMAZOLE 1% 20G VAG CREAM","کرم واژینال کلوتریمازول ۱ درصد ۲۰ گرم",{"code":209,"en":210,"fa":211},"00327","CLOTRIMAZOLE 1% 20ML TOP SOLUTION","محلول کلوتریمازول ۱ درصد ۲۰ میلی‌لیتر",{"code":213,"en":214,"fa":215},"00325","CLOTRIMAZOLE 1% 50G VAG CREAM","کرم واژینال کلوتریمازول ۱ درصد ۵۰ گرم",{"code":217,"en":218,"fa":219},"13803","CLOTRIMAZOLE 100MG VAG SUPP","شیاف کلوتریمازول ۱۰۰ میلی‌گرم",{"code":221,"en":222,"fa":223},"00328","CLOTRIMAZOLE 100MG VAG TAB","قرص واژینال کلوتریمازول ۱۰۰ میلی‌گرم",{"code":225,"en":226,"fa":227},"02230","CLOTRIMAZOLE 2% 20G VAG CREAM","کرم واژینال کلوتریمازول ۲ درصد ۲۰ گرم",{"code":229,"en":230,"fa":231},"11225","CLOTRIMAZOLE 2% 50G VAG CREAM","کرم واژینال کلوتریمازول ۲ درصد ۵۰ گرم",{"code":233,"en":234,"fa":235},"16817","CLOTRIMAZOLE 200MG PESSARY","کلوتریمازول ۲۰۰ میلی‌گرم پسساری",{"code":237,"en":238,"fa":239},"16850","CLOTRIMAZOLE 500MG PESSARY","کلوتریمازول ۵۰۰ میلی‌گرم پسساری",{"code":241,"en":242,"fa":243},"02426","CLOTRIMAZOLE 500MG VAG TAB","قرص واژینال کلوتریمازول ۵۰۰ میلی‌گرم",{"code":245,"en":246,"fa":247},"51866","CLOTRIMAZOLE CREAM VAGINAL 2 % 50 g","کرم کلوتریمازول ۲ درصد ۵۰ گرم",[249],{"source":250,"section":251,"url":252},"darooyab-generic","G-708\u002FClotrimazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-708\u002FClotrimazole",[254,258,262,266,269,272,274,278],{"kind":255,"url":256,"label":257},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=215641","ANDA215641",{"kind":259,"url":260,"label":261},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=980736aa-751a-4642-ab85-a309435fd02f","FDA Clotrimazole troche",{"kind":263,"url":264,"label":265},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa618058.html","Clotrimazole Lozenge",{"kind":263,"url":267,"label":268},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa618059.html","Clotrimazole Topical",{"kind":270,"url":271,"label":196},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=D01AC01",{"kind":273,"url":252,"label":8},"darooyab",{"kind":275,"url":276,"label":277},"emc","https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F1282\u002Fsmpc","UK SmPC Canesten cream",{"kind":275,"url":279,"label":280},"https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F2042\u002Fsmpc","UK SmPC Canesten pess.",{"pregnancy":282,"pediatric":291,"geriatric":298},{"level":283,"text":284,"quote":287,"refs":288},"caution",{"fa":285,"en":286},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Clotrimazole lozenges should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[289],{"source":59,"section":290},"Pregnancy Category C:",{"level":283,"text":292,"quote":295,"refs":296},{"fa":293,"en":294},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of clotrimazole in children below the age of 3 years have not been established; therefore, its use in such patients is not recommended.",[297],{"source":59,"section":153},{"level":283,"text":299,"quote":302,"refs":303},{"fa":300,"en":301},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of clotrimazole did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.",[304],{"source":59,"section":305},"Geriatric Use",{"kind":307,"refs":308,"id":257},"ANDA",[309],{"source":59,"section":310},"SPL approval \u002F marketing category",1792444703967]