Sulfamethoxazole-trimethoprim (co-trimoxazole)

🧮 Dose calculator

Urinary tract infection · Regimen source: FDA TMP-SMX susp · Dosage and Administration

• • Dose is calculated and shown as the trimethoprim component. FDA TMP-SMX susp · Dosage and Administration

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👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA TMP-SMX susp · PREGNANCY

  “Because sulfamethoxazole and trimethoprim may interfere with folic acid metabolism, sulfamethoxazole and trimethoprim should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA TMP-SMX susp · NURSING MOTHERS

  “Caution should be exercised when sulfamethoxazole and trimethoprim is administered to a nursing woman, especially when breastfeeding, jaundiced, ill, stressed, or premature infants because of the potential risk of bilirubin displacement and kernicterus.”

• 👶 ChildrenContraindicated

  Label: contraindicated in children below a stated age. FDA TMP-SMX susp · CONTRAINDICATIONS

  “… ombocytopenia with use of trimethoprim and/or sulfonamides • documented megaloblastic anemia due to folate deficiency • pediatric patients less than 2 months of age • marked hepatic damage • severe renal insufficiency when renal function status cannot be monitored • concomitant administration with dofetilide (see …”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA TMP-SMX susp · GERIATRIC USE

  “There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e.g., impaired kidney and/or liver function, possible folate deficiency, or concomitant use of other drugs.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.