Desloratadine
دسلوراتادین
🌬️ Respiratory SystemSecond-generation antihistamine
Market / country: 🇬🇧 UK🇺🇸 USA
Clarinex (US) · Neoclarityn (GB)
🧮 Dose calculator
Allergic rhinitis · Regimen source: UK SmPC Neoclarityn · 4.2UK SmPC Neoclarityn · 4.1
- • Most rhinitis under 2 years is infectious; no data for infectious rhinitis. Safety below 1 year not established. UK SmPC Neoclarityn · 4.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to desloratadine or loratadine. UK SmPC Neoclarityn · 4.3FDA Desloratadine · 4
Warnings
- • Caution with personal or family history of seizures, mainly young children. UK SmPC Neoclarityn · 4.4
- • Severe renal insufficiency: use with caution. UK SmPC Neoclarityn · 4.4
Formulations
- 0.5 mg / mL oral solution — solution 🇬🇧 UK UK SmPC Neoclarityn · 2
- 5 mg tablet — tablet 🇺🇸 USA FDA Desloratadine · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Desloratadine · 8.1
“Risk Summary The limited available data with desloratadine in pregnant women are not sufficient to inform a drug-associated risk for major birth defects and miscarriage.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Desloratadine · 8.2
“Risk Summary Desloratadine passes into breast milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Desloratadine · 8.4
“The recommended dose of desloratadine oral solution in the pediatric population is based on cross-study comparison of the plasma concentration of desloratadine in adults and pediatric subjects.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Desloratadine · 8.5
“In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Desloratadine · 8.3
“Infertility There are no data available on human infertility associated with desloratadine.”
🔗 Reference links
- FDA (approval record)ANDA078352
- DailyMed (FDA label)FDA Desloratadine
- MedlinePlus (NIH)Desloratadine
- WHO ATC/DDDR06AX27
- Darooyab (Iran)Desloratadine
- eMC (UK label)UK SmPC Neoclarityn
🇮🇷 Registered in Iran Darooyab · G-788/Desloratadine
Dosage forms with Iranian generic codes, per Darooyab.
- 09633 · DESLORATADINE 5MG TAB · قرص دسلوراتادین ۵ میلیگرم
- 09634 · DESLORATADINE SYRUP · شربت دسلوراتادین
- 52136 · DESLORATADINE TABLET ORAL 5 mg · قرص دسلوراتادین ۵ میلیگرم
- 52148 · DESLORATADINE SYRUP ORAL 2.5 mg/5 mL 120 mL · شربت دسلوراتادین ۲٫۵ میلیگرم / ۵ میلیلیتر ۱۲۰ میلیلیتر
- 52990 · DESLORATADINE SYRUP ORAL 2.5 mg/5 mL 60 mL · شربت دسلوراتادین ۲٫۵ میلیگرم / ۵ میلیلیتر ۶۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Desloratadine · 3FDA Desloratadine · 2.1FDA Desloratadine · 4FDA Desloratadine · 8.1FDA Desloratadine · 8.2FDA Desloratadine · 8.4FDA Desloratadine · 8.5FDA Desloratadine · 8.3FDA Desloratadine · SPL approval / marketing category
- UK SmPC (eMC / MHRA)✅ PresentUK SmPC Neoclarityn · 2UK SmPC Neoclarityn · 4.2UK SmPC Neoclarityn · 4.1UK SmPC Neoclarityn · 4.3UK SmPC Neoclarityn · 4.4
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-788/Desloratadine
- Clinical review⚠ Unverified