Esomeprazole
ازومپرازول
🍽️ Alimentary Tract And MetabolismProton-pump inhibitor
Market / country: 🇺🇸 USA
Nexium (US)
🧮 Dose calculator
Erosive esophagitis (GERD) · Regimen source: FDA Nexium · 2.1, Table 1
- • At least 1 h before meals; swallow whole. Severe liver impairment: max 20 mg. Maintenance: 20 mg daily. FDA Nexium · 2.1, Table 1FDA Nexium · 2.3
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to substituted benzimidazoles (anaphylaxis, angioedema, interstitial nephritis). FDA Nexium · 4
Formulations
- 20 mg capsule — capsule 🇺🇸 USA FDA Nexium · 3
- 40 mg capsule — capsule 🇺🇸 USA FDA Nexium · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Nexium · 8.1
“Risk Summary There are no adequate and well-controlled studies with esomeprazole in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Nexium · 8.2
“Risk Summary Esomeprazole is the S-isomer of omeprazole and limited data suggest that omeprazole may be present in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Nexium · 8.4
“Healing of EE Pediatric Patients 1 Year to 17 Years of Age The safety and effectiveness of NEXIUM delayed-release capsules and NEXIUM for delayed-release oral suspension have been established in pediatric patients 12 years to 17 years for short-term treatment (4 to 8 weeks) for healing of EE.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Nexium · 8.5
“Of the total number of patients who received NEXIUM in clinical trials, 1459 were 65 to 74 years of age and 354 patients were 75 years of age and older.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA021153
- DailyMed (FDA label)FDA Nexium
- MedlinePlus (NIH)EsomeprazoleEsomeprazole Injection
- WHO ATC/DDDA02BC05
- Darooyab (Iran)Esomeprazole
🇮🇷 Registered in Iran Darooyab · G-2582/Esomeprazole
Dosage forms with Iranian generic codes, per Darooyab.
- 18013 · ESOMEPRAZOLE 10 MG GRANULE · گرانول ازومپرازول ۱۰ میلیگرم
- 16306 · ESOMEPRAZOLE 10MG SACHET · ساشه ازومپرازول ۱۰ میلیگرم
- 13973 · ESOMEPRAZOLE 20MG CAP · کپسول ازومپرازول ۲۰ میلیگرم
- 05922 · ESOMEPRAZOLE 20MG TAB · قرص ازومپرازول ۲۰ میلیگرم
- 13974 · ESOMEPRAZOLE 40MG CAP · کپسول ازومپرازول ۴۰ میلیگرم
- 05923 · ESOMEPRAZOLE 40MG TAB · قرص ازومپرازول ۴۰ میلیگرم
- 52188 · ESOMEPRAZOLE 5 MG GRANULE · گرانول ازومپرازول ۵ میلیگرم
- 52675 · ESOMEPRAZOLE 2.5 MG GRANULE · گرانول ازومپرازول ۲٫۵ میلیگرم
- 52085 · ESOMEPRAZOLE (AS MAGNESIUM) GRANULE, DELAYED RELEASE ORAL 10 mg · گرانول ازومپرازول (معادل منیزیم) ۱۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Nexium · 3FDA Nexium · 2.1, Table 1FDA Nexium · 2.3FDA Nexium · 2.2, Table 2FDA Nexium · 4FDA Nexium · 8.1FDA Nexium · 8.2FDA Nexium · 8.4FDA Nexium · 8.5FDA Nexium · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2582/Esomeprazole
- Clinical review⚠ Unverified