[{"data":1,"prerenderedAt":301},["ShallowReactive",2],{"drug-fluconazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":78,"contraindications":142,"warnings":162,"renal":163,"monitoring":164,"interactions":165,"review":166,"examples":169,"atc":182,"iran":184,"links":240,"populations":260,"usApproval":296},"fluconazole",1,{"fa":7,"en":8},"فلوکونازول","Fluconazole","anti-infectives",{"fa":11,"en":12},"ضدقارچ آزول","Azole antifungal",[14],{"name":15,"market":16},"Diflucan","US",[18,19,7,20],"diflucan","دیفلوکان","قرص قارچ واژن",[22,36,44,52,60,70],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-50","tablet","oral","50 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},50,"mg",false,[16],[33],{"source":34,"section":35},"fda-diflucan","How Supplied",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-100","100 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":30},100,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"tab-150","150 mg tablet",{"amount":48,"unit":29,"perUnit":24,"scored":30},150,[16],[51],{"source":34,"section":35},{"id":53,"form":24,"route":25,"label":54,"concentration":55,"markets":57,"refs":58},"tab-200","200 mg tablet",{"amount":56,"unit":29,"perUnit":24,"scored":30},200,[16],[59],{"source":34,"section":35},{"id":61,"form":62,"route":25,"label":63,"concentration":64,"markets":66,"refs":67},"susp-10","suspension","10 mg\u002FmL oral suspension (reconstituted)",{"amount":65,"unit":29,"perVolumeMl":5},10,[16],[68],{"source":34,"section":69},"Directions for Mixing the Oral Suspension",{"id":71,"form":62,"route":25,"label":72,"concentration":73,"markets":75,"refs":76},"susp-40","40 mg\u002FmL oral suspension (reconstituted)",{"amount":74,"unit":29,"perVolumeMl":5},40,[16],[77],{"source":34,"section":69},[79,95,115],{"id":80,"disease":81,"label":82,"population":85,"type":89,"unit":29,"dose":90,"refs":91,"durationDays":94},"vaginal","vaginal-candidiasis",{"fa":83,"en":84},"کاندیدیاز واژن: ۱۵۰ mg خوراکی تک‌دوز","Vaginal candidiasis: 150 mg orally, single dose",{"minAge":86},{"value":87,"unit":88},18,"year","fixed",{"perDose":48,"dosesPerDay":5},[92],{"source":34,"section":93},"Dosage and Administration in Adults",{"min":5,"max":5},{"id":96,"disease":97,"label":98,"population":101,"type":89,"unit":29,"dose":103,"refs":104,"durationDays":106,"notes":108},"thrush-adult","oral-candidiasis",{"fa":99,"en":100},"برفک دهان — بزرگسال: روز اول ۲۰۰ mg، سپس ۱۰۰ mg روزانه","Oropharyngeal candidiasis — adults: 200 mg day 1, then 100 mg daily",{"minAge":102},{"value":87,"unit":88},{"perDose":40,"dosesPerDay":5},[105],{"source":34,"section":93},{"min":107,"max":107},14,[109],{"text":110,"refs":113},{"fa":111,"en":112},"روز اول ۲۰۰ mg. حداقل ۲ هفته برای کاهش عود. ازوفاژیت: همین دوز، تا ۴۰۰ mg\u002Fday، حداقل ۳ هفته.","Day 1: 200 mg. At least 2 weeks to reduce relapse. Esophagitis: same, up to 400 mg\u002Fday, at least 3 weeks.",[114],{"source":34,"section":93},{"id":116,"disease":97,"label":117,"population":120,"type":125,"unit":29,"dose":126,"refs":132,"notes":135},"thrush-peds",{"fa":118,"en":119},"برفک دهان — ۶ ماه به بالا: روز اول ۶ mg\u002Fkg، سپس ۳ mg\u002Fkg روزانه","Oropharyngeal candidiasis — ≥6 months: 6 mg\u002Fkg day 1, then 3 mg\u002Fkg daily",{"minAge":121,"maxAge":124},{"value":122,"unit":123},6,"month",{"value":87,"unit":88},"loading",{"dividedDoses":5,"days":127},[128,129],{"fromDay":5,"toDay":5,"perKgPerDay":122},{"fromDay":130,"toDay":107,"perKgPerDay":131},2,3,[133],{"source":34,"section":134},"Dosage and Administration in Pediatric Patients",[136],{"text":137,"refs":140},{"fa":138,"en":139},"حداقل ۲ هفته. ازوفاژیت: همین دوز، تا ۱۲ mg\u002Fkg\u002Fday.","At least 2 weeks. Esophagitis: same, up to 12 mg\u002Fkg\u002Fday.",[141],{"source":34,"section":134},[143,152],{"id":144,"severity":145,"text":146,"refs":149},"ci","block",{"fa":147,"en":148},"حساسیت به فلوکونازول؛ همراه داروهای طولانی‌کننده QT که با CYP3A4 متابولیزه می‌شوند (اریترومایسین، پیموزاید، کینیدین).","Hypersensitivity to fluconazole; with QT-prolonging CYP3A4 substrates (erythromycin, pimozide, quinidine).",[150],{"source":34,"section":151},"Contraindications",{"id":153,"severity":154,"rule":155,"text":157,"refs":160},"under-6m","warn",{"maxAge":156},{"value":122,"unit":123},{"fa":158,"en":159},"دوز برفک در کودکان از ۶ ماه به بالا است.","Pediatric thrush dosing is for 6 months and older.",[161],{"source":34,"section":134},[],[],[],[],{"status":167,"reviewer":168,"date":168},"unverified",null,[170,175,179],{"regimen":80,"formulation":45,"input":171,"expect":174},{"ageYears":172,"weightKg":173},30,60,{"perDose":48},{"regimen":96,"formulation":37,"input":176,"expect":178},{"ageYears":74,"weightKg":177},70,{"perDose":40},{"regimen":116,"formulation":61,"input":180,"expect":181},{"ageYears":5,"weightKg":65},{"perDose":173,"mlPerDose":122},[183],"J02AC01",{"status":185,"forms":186,"refs":235},"registered",[187,191,195,199,203,207,211,215,219,223,227,231],{"code":188,"en":189,"fa":190},"00537","FLUCONAZOLE 100MG CAP","کپسول فلوکونازول ۱۰۰ میلی‌گرم",{"code":192,"en":193,"fa":194},"02127","FLUCONAZOLE 100MG TAB","قرص فلوکونازول ۱۰۰ میلی‌گرم",{"code":196,"en":197,"fa":198},"08530","FLUCONAZOLE 100MG\u002F50ML INF","محلول انفوزیون فلوکونازول ۱۰۰ میلی‌گرم \u002F ۵۰ میلی‌لیتر",{"code":200,"en":201,"fa":202},"00538","FLUCONAZOLE 150MG CAP","کپسول فلوکونازول ۱۵۰ میلی‌گرم",{"code":204,"en":205,"fa":206},"02128","FLUCONAZOLE 150MG TAB","قرص فلوکونازول ۱۵۰ میلی‌گرم",{"code":208,"en":209,"fa":210},"02432","FLUCONAZOLE 200MG CAP","کپسول فلوکونازول ۲۰۰ میلی‌گرم",{"code":212,"en":213,"fa":214},"02433","FLUCONAZOLE 200MG TAB","قرص فلوکونازول ۲۰۰ میلی‌گرم",{"code":216,"en":217,"fa":218},"08529","FLUCONAZOLE 200MG\u002F100ML INJ","فرآورده تزریقی فلوکونازول ۲۰۰ میلی‌گرم \u002F ۱۰۰ میلی‌لیتر",{"code":220,"en":221,"fa":222},"11393","FLUCONAZOLE 200MG\u002F5ML SUSPENSION","فلوکونازول ۲۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":224,"en":225,"fa":226},"22000","FLUCONAZOLE 400MG\u002F200ML INJ","فرآورده تزریقی فلوکونازول ۴۰۰ میلی‌گرم \u002F ۲۰۰ میلی‌لیتر",{"code":228,"en":229,"fa":230},"00540","FLUCONAZOLE 50MG CAP","کپسول فلوکونازول ۵۰ میلی‌گرم",{"code":232,"en":233,"fa":234},"02129","FLUCONAZOLE 50MG TAB","قرص فلوکونازول ۵۰ میلی‌گرم",[236],{"source":237,"section":238,"url":239},"darooyab-generic","G-717\u002FFluconazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-717\u002FFluconazole",[241,245,249,252,255,258],{"kind":242,"url":243,"label":244},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=019949","NDA019949",{"kind":246,"url":247,"label":248},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=f694c617-3383-416c-91b6-b94fda371204","FDA Diflucan",{"kind":250,"url":251,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa690002.html",{"kind":250,"url":253,"label":254},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601143.html","Fluconazole Injection",{"kind":256,"url":257,"label":183},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J02AC01",{"kind":259,"url":239,"label":8},"darooyab",{"pregnancy":261,"lactation":270,"pediatric":279,"geriatric":288},{"level":262,"text":263,"quote":266,"refs":267},"avoid",{"fa":264,"en":265},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Teratogenic Effects Potential for Fetal Harm: Use in pregnancy should be avoided except in patients with severe or potentially life-threatening fungal infections in whom fluconazole may be used if the anticipated benefit outweighs the possible risk to the fetus.",[268],{"source":34,"section":269},"Pregnancy",{"level":271,"text":272,"quote":275,"refs":276},"caution",{"fa":273,"en":274},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Caution should be exercised when DIFLUCAN is administered to a nursing woman.",[277],{"source":34,"section":278},"Nursing Mothers",{"level":280,"text":281,"quote":284,"refs":285},"not-established",{"fa":282,"en":283},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Use in Prophylaxis of Invasive Candida Infections in Pediatric Patients (premature infants weighing less than 750 grams at birth) Safety and effectiveness of DIFLUCAN for the prophylaxis of invasive candidiasis in pediatric patients (premature infants weighing less than 750 grams at birth) have not been established.",[286],{"source":34,"section":287},"Pediatric Use",{"level":271,"text":289,"quote":292,"refs":293},{"fa":290,"en":291},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","It may be useful to monitor renal function.",[294],{"source":34,"section":295},"Geriatric Use",{"kind":297,"refs":298,"id":244},"NDA",[299],{"source":34,"section":300},"SPL approval \u002F marketing category",1792440730427]