[{"data":1,"prerenderedAt":313},["ShallowReactive",2],{"drug-fluticasone-salmeterol":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":27,"regimens":79,"contraindications":134,"warnings":154,"renal":155,"monitoring":156,"interactions":157,"review":158,"examples":161,"atc":180,"iran":182,"links":254,"populations":275,"usApproval":308},"fluticasone-salmeterol",1,{"fa":7,"en":8},"فلوتیکازون-سالمترول (سرتاید)","Fluticasone\u002Fsalmeterol","respiratory",{"fa":11,"en":12},"ICS + LABA استنشاقی","Inhaled ICS + LABA",[14,17],{"name":15,"market":16},"Advair Diskus","US",{"name":18,"market":19},"Seretide","GB",[21,22,23,24,25,26],"advair","seretide","سرتاید","سروتاید","فلوتیکازون سالمترول","اسپری آسم",[28,53,66],{"id":29,"form":30,"route":31,"label":32,"concentration":33,"components":36,"markets":48,"refs":49},"diskus-100-50","inhaler","inhaled","100\u002F50 mcg per inhalation (fluticasone\u002Fsalmeterol)",{"amount":5,"unit":34,"perUnit":35},"spray","actuation",{"fluticasone":37,"salmeterol":43},{"name":38,"amount":41,"unit":42},{"fa":39,"en":40},"فلوتیکازون","Fluticasone",100,"mcg",{"name":44,"amount":47,"unit":42},{"fa":45,"en":46},"سالمترول","Salmeterol",50,[16],[50],{"source":51,"section":52},"fda-advair","3",{"id":54,"form":30,"route":31,"label":55,"concentration":56,"components":57,"markets":63,"refs":64},"diskus-250-50","250\u002F50 mcg per inhalation (fluticasone\u002Fsalmeterol)",{"amount":5,"unit":34,"perUnit":35},{"fluticasone":58,"salmeterol":61},{"name":59,"amount":60,"unit":42},{"fa":39,"en":40},250,{"name":62,"amount":47,"unit":42},{"fa":45,"en":46},[16],[65],{"source":51,"section":52},{"id":67,"form":30,"route":31,"label":68,"concentration":69,"components":70,"markets":76,"refs":77},"diskus-500-50","500\u002F50 mcg per inhalation (fluticasone\u002Fsalmeterol)",{"amount":5,"unit":34,"perUnit":35},{"fluticasone":71,"salmeterol":74},{"name":72,"amount":73,"unit":42},{"fa":39,"en":40},500,{"name":75,"amount":47,"unit":42},{"fa":45,"en":46},[16],[78],{"source":51,"section":52},[80,108,121],{"id":81,"disease":82,"label":83,"population":86,"type":90,"unit":34,"dose":91,"refs":93,"limits":96,"notes":100},"asthma-12","asthma",{"fa":84,"en":85},"آسم — ۱۲ سال به بالا: ۱ استنشاق دو بار در روز","Asthma — ≥12 y: 1 inhalation twice daily",{"minAge":87},{"value":88,"unit":89},12,"year","fixed",{"perDose":5,"dosesPerDay":92},2,[94],{"source":51,"section":95},"2.1",{"maxPerDay":92,"refs":97},[98],{"source":51,"section":99},"2",[101],{"text":102,"refs":105},{"fa":103,"en":104},"قوت ۱۰۰\u002F۵۰، ۲۵۰\u002F۵۰ یا ۵۰۰\u002F۵۰ بر اساس شدت و دوز ICS قبلی. بیش از ۱ استنشاق دو بار توصیه نمی‌شود. برای حمله حاد نیست.","Strength 100\u002F50, 250\u002F50 or 500\u002F50 by severity and prior ICS dose. More than 1 inhalation twice daily not recommended. Not for acute attacks.",[106,107],{"source":51,"section":95},{"source":51,"section":99},{"id":109,"disease":82,"label":110,"population":113,"type":90,"unit":34,"dose":117,"refs":118,"allowedFormulations":120},"asthma-4-11",{"fa":111,"en":112},"آسم — ۴ تا ۱۱ سال: ۱ استنشاق ۱۰۰\u002F۵۰ دو بار","Asthma — 4–11 y: 1 inhalation of 100\u002F50 twice daily",{"minAge":114,"maxAge":116},{"value":115,"unit":89},4,{"value":88,"unit":89},{"perDose":5,"dosesPerDay":92},[119],{"source":51,"section":95},[29],{"id":122,"disease":122,"label":123,"population":126,"type":90,"unit":34,"dose":129,"refs":130,"allowedFormulations":133},"copd",{"fa":124,"en":125},"COPD — ۱ استنشاق ۲۵۰\u002F۵۰ دو بار","COPD — 1 inhalation of 250\u002F50 twice daily",{"minAge":127},{"value":128,"unit":89},18,{"perDose":5,"dosesPerDay":92},[131],{"source":51,"section":132},"2.2",[54],[135,144],{"id":136,"severity":137,"text":138,"refs":141},"ci","block",{"fa":139,"en":140},"درمان اولیه حمله حاد آسم یا COPD؛ حساسیت شدید به پروتئین شیر یا اجزا.","Primary treatment of status asthmaticus or acute COPD episodes; severe milk-protein or component hypersensitivity.",[142],{"source":51,"section":143},"4",{"id":145,"severity":137,"rule":146,"text":148,"refs":151},"under-4",{"maxAge":147},{"value":115,"unit":89},{"fa":149,"en":150},"زیر ۴ سال ثابت نشده.","Not established under 4 years.",[152],{"source":51,"section":153},"8.4",[],[],[],[],{"status":159,"reviewer":160,"date":160},"unverified",null,[162,167,172,176],{"regimen":81,"formulation":54,"input":163,"expect":166},{"ageYears":164,"weightKg":165},30,70,{"perDose":5,"perDay":92},{"regimen":109,"formulation":29,"input":168,"expect":171},{"ageYears":169,"weightKg":170},8,25,{"perDose":5},{"regimen":109,"formulation":54,"input":173,"expect":174},{"ageYears":169,"weightKg":170},{"status":175},"blocked",{"regimen":122,"formulation":54,"input":177,"expect":179},{"ageYears":178,"weightKg":165},65,{"perDose":5},[181],"R03AK06",{"status":183,"forms":184,"refs":249},"registered",[185,189,193,197,201,205,209,213,217,221,225,229,233,237,241,245],{"code":186,"en":187,"fa":188},"13467","FLUTICASON FUROATE 27.5MCG 120DOSE NASAL SPRAY","اسپری بینی فلوتیکاسون فوروات ۲۷٫۵ میکروگرم ۱۲۰ دوز",{"code":190,"en":191,"fa":192},"02711","FLUTICASONE 125MCG\u002FDOSE 120DOSE SPRAY","اسپری فلوتیکازون ۱۲۵ میکروگرم \u002F دوز ۱۲۰ دوز",{"code":194,"en":195,"fa":196},"01889","FLUTICASONE 125MCG\u002FDOSE 60DOSE SPRAY","اسپری فلوتیکازون ۱۲۵ میکروگرم \u002F دوز ۶۰ دوز",{"code":198,"en":199,"fa":200},"15910","FLUTICASONE 125MCG\u002FDOSE DPI INHALER","فرآورده استنشاقی فلوتیکازون ۱۲۵ میکروگرم \u002F دوز دپی",{"code":202,"en":203,"fa":204},"02710","FLUTICASONE 250MCG\u002FDOSE 120DOSE SPRAY","اسپری فلوتیکازون ۲۵۰ میکروگرم \u002F دوز ۱۲۰ دوز",{"code":206,"en":207,"fa":208},"02052","FLUTICASONE 250MCG\u002FDOSE 60DOSE SPRAY","اسپری فلوتیکازون ۲۵۰ میکروگرم \u002F دوز ۶۰ دوز",{"code":210,"en":211,"fa":212},"15909","FLUTICASONE 250MCG\u002FDOSE DPI INHALER","فرآورده استنشاقی فلوتیکازون ۲۵۰ میکروگرم \u002F دوز دپی",{"code":214,"en":215,"fa":216},"14541","FLUTICASONE 50MCG\u002FDOSE 100DOSE NASAL SPRAY","اسپری بینی فلوتیکازون ۵۰ میکروگرم \u002F دوز ۱۰۰ دوز",{"code":218,"en":219,"fa":220},"05290","FLUTICASONE 50MCG\u002FDOSE 120DOSE 15ML NASAL SPRAY","اسپری بینی فلوتیکازون ۵۰ میکروگرم \u002F دوز ۱۲۰ دوز ۱۵ میلی‌لیتر",{"code":222,"en":223,"fa":224},"17124","FLUTICASONE 50MCG\u002FDOSE 200DOSE 20ML NASAL SPRAY","اسپری بینی فلوتیکازون ۵۰ میکروگرم \u002F دوز ۲۰۰ دوز ۲۰ میلی‌لیتر",{"code":226,"en":227,"fa":228},"02053","FLUTICASONE 50MCG\u002FDOSE SPRAY","اسپری فلوتیکازون ۵۰ میکروگرم \u002F دوز",{"code":230,"en":231,"fa":232},"51238","FLUTICASONE FUROATE SPRAY, METERED NASAL 27.5 ug\u002F1 {Puff} 120 {Puff}","فرآورده استنشاقی فلوتیکازون فوروات ۲۷٫۵ میکروگرم \u002F ۱ { } ۱۲۰ { }",{"code":234,"en":235,"fa":236},"52149","FLUTICASONE PROPIONATE SPRAY NASAL 50 ug\u002F1{Puff} 120 {Puff}","اسپری بینی فلوتیکازون پروپیونات ۵۰ میکروگرم \u002F ۱ { } ۱۲۰ { }",{"code":238,"en":239,"fa":240},"52343","FLUTICASONE PROPIONATE SPRAY NASAL 50 ug\u002F1{Puff} 100 {Puff}","اسپری بینی فلوتیکازون پروپیونات ۵۰ میکروگرم \u002F ۱ { } ۱۰۰ { }",{"code":242,"en":243,"fa":244},"52821","FLUTICASONE PROPIONATE POWDER, METERED RESPIRATORY 250 ug\u002F1{dose} 60 {dose}","پودر فلوتیکازون پروپیونات ۲۵۰ میکروگرم \u002F ۱ { دوز } ۶۰ { دوز }",{"code":246,"en":247,"fa":248},"51941","FLUTICASONE PROPIONATE SPRAY NASAL 50 ug\u002F1{Puff} 60 {Puff}","اسپری بینی فلوتیکازون پروپیونات ۵۰ میکروگرم \u002F ۱ { } ۶۰ { }",[250],{"source":251,"section":252,"url":253},"darooyab-generic","G-2108\u002FFluticasone","https:\u002F\u002Fwww.darooyab.ir\u002FG-2108\u002FFluticasone",[255,259,263,267,270,273],{"kind":256,"url":257,"label":258},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021077","NDA021077",{"kind":260,"url":261,"label":262},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=4eeb5f6a-593f-4a9e-9692-adefa2caf8fc","FDA Advair Diskus",{"kind":264,"url":265,"label":266},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa695002.html","Fluticasone Nasal Spray",{"kind":264,"url":268,"label":269},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601056.html","Fluticasone Oral Inhalation",{"kind":271,"url":272,"label":181},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R03AK06",{"kind":274,"url":253,"label":40},"darooyab",{"pregnancy":276,"lactation":285,"pediatric":293,"geriatric":300},{"level":277,"text":278,"quote":281,"refs":282},"caution",{"fa":279,"en":280},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are insufficient data on the use of ADVAIR DISKUS or individual monoproducts, fluticasone propionate and salmeterol xinafoate, in pregnant women.",[283],{"source":51,"section":284},"8.1",{"level":277,"text":286,"quote":289,"refs":290},{"fa":287,"en":288},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no available data on the presence of fluticasone propionate or salmeterol in human milk, the effects on the breastfed child, or the effects on milk production.",[291],{"source":51,"section":292},"8.2",{"level":277,"text":294,"quote":297,"refs":298},{"fa":295,"en":296},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of ADVAIR DISKUS in children with asthma younger than 4 years have not been established.",[299],{"source":51,"section":153},{"level":277,"text":301,"quote":304,"refs":305},{"fa":302,"en":303},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","As with other products containing beta 2 -agonists, special caution should be observed when using ADVAIR DISKUS in geriatric patients who have concomitant cardiovascular disease that could be adversely affected by beta 2 -agonists.",[306],{"source":51,"section":307},"8.5",{"kind":309,"refs":310,"id":258},"NDA",[311],{"source":51,"section":312},"SPL approval \u002F marketing category",1792444716380]