[{"data":1,"prerenderedAt":298},["ShallowReactive",2],{"drug-lansoprazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":44,"contraindications":161,"warnings":181,"renal":182,"monitoring":183,"interactions":184,"review":185,"examples":187,"atc":214,"iran":216,"links":240,"populations":260,"usApproval":293},"lansoprazole",1,{"fa":7,"en":8},"لانسوپرازول","Lansoprazole","alimentary-metabolism",{"fa":11,"en":12},"مهارکننده پمپ پروتون","Proton-pump inhibitor",[14],{"name":15,"market":16},"Prevacid","US",[18,19,7,20],"prevacid","پرواسید","PPI",[22,36],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"cap-15","capsule","oral","15 mg capsule",{"amount":28,"unit":29,"perUnit":24,"scored":30},15,"mg",false,[16],[33],{"source":34,"section":35},"fda-lansoprazole","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"cap-30","30 mg capsule",{"amount":40,"unit":29,"perUnit":24,"scored":30},30,[16],[43],{"source":34,"section":35},[45,69,91,113,142],{"id":46,"disease":47,"label":48,"population":51,"type":55,"unit":29,"dose":56,"refs":57,"durationDays":60,"notes":62},"du","peptic-ulcer-disease",{"fa":49,"en":50},"زخم دوازدهه — ۱۵ mg یک بار، ۴ هفته","Duodenal ulcer — 15 mg once daily for 4 weeks",{"minAge":52},{"value":53,"unit":54},18,"year","fixed",{"perDose":28,"dosesPerDay":5},[58],{"source":34,"section":59},"2.1",{"min":61,"max":61},28,[63],{"text":64,"refs":67},{"fa":65,"en":66},"نگهدارنده پس از بهبود: ۱۵ mg روزانه.","Maintenance after healing: 15 mg daily.",[68],{"source":34,"section":59},{"id":70,"disease":71,"label":72,"population":75,"type":55,"unit":29,"dose":77,"refs":79,"durationDays":81,"notes":84},"hp","h-pylori",{"fa":73,"en":74},"ریشه‌کنی H. pylori (سه‌دارویی) — ۳۰ mg دو بار، ۱۰ یا ۱۴ روز","H. pylori triple therapy — 30 mg twice daily for 10 or 14 days",{"minAge":76},{"value":53,"unit":54},{"perDose":40,"dosesPerDay":78},2,[80],{"source":34,"section":59},{"min":82,"max":83},10,14,[85],{"text":86,"refs":89},{"fa":87,"en":88},"همراه آموکسی‌سیلین و کلاریترومایسین طبق برچسب.","With amoxicillin and clarithromycin per label.",[90],{"source":34,"section":59},{"id":92,"disease":93,"label":94,"population":97,"type":55,"unit":29,"dose":99,"refs":100,"durationDays":102,"notes":104},"ee","erosive-esophagitis",{"fa":95,"en":96},"ازوفاژیت اروزیو — ۳۰ mg یک بار تا ۸ هفته","Erosive oesophagitis — 30 mg once daily up to 8 weeks",{"minAge":98},{"value":53,"unit":54},{"perDose":40,"dosesPerDay":5},[101],{"source":34,"section":59},{"min":103,"max":103},56,[105],{"text":106,"refs":109},{"fa":107,"en":108},"نگهدارنده: ۱۵ mg روزانه. نارسایی شدید کبد: ۱۵ mg.","Maintenance: 15 mg daily. Severe liver impairment: 15 mg.",[110,111],{"source":34,"section":59},{"source":34,"section":112},"2.3",{"id":114,"disease":115,"label":116,"population":119,"type":123,"unit":29,"dose":124,"refs":130,"durationDays":133,"notes":135},"peds-1-11","gerd",{"fa":117,"en":118},"GERD\u002Fازوفاژیت — ۱ تا ۱۱ سال: بر اساس وزن تا ۱۲ هفته","GERD\u002Foesophagitis — 1–11 y: by weight, up to 12 weeks",{"minAge":120,"maxAge":121},{"value":5,"unit":54},{"value":122,"unit":54},12,"weightBand",{"weightBands":125},[126,128],{"minWeightKg":127,"maxWeightKg":40,"perDose":28,"dosesPerDay":5},0,{"minWeightKg":40,"maxWeightKg":129,"perDose":40,"dosesPerDay":5},null,[131],{"source":34,"section":132},"2.2",{"min":134,"max":134},84,[136],{"text":137,"refs":140},{"fa":138,"en":139},"۳۰ kg و کمتر: ۱۵ mg؛ بالای ۳۰ kg: ۳۰ mg.","≤30 kg: 15 mg; >30 kg: 30 mg.",[141],{"source":34,"section":132},{"id":143,"disease":115,"label":144,"population":147,"type":55,"unit":29,"dose":150,"refs":151,"durationDays":153,"notes":154},"peds-12-17",{"fa":145,"en":146},"GERD غیراروزیو — ۱۲ تا ۱۷ سال: ۱۵ mg تا ۸ هفته","Non-erosive GERD — 12–17 y: 15 mg up to 8 weeks",{"minAge":148,"maxAge":149},{"value":122,"unit":54},{"value":53,"unit":54},{"perDose":28,"dosesPerDay":5},[152],{"source":34,"section":132},{"min":103,"max":103},[155],{"text":156,"refs":159},{"fa":157,"en":158},"ازوفاژیت اروزیو در این سن: ۳۰ mg تا ۸ هفته.","Erosive oesophagitis at this age: 30 mg up to 8 weeks.",[160],{"source":34,"section":132},[162,171],{"id":163,"severity":164,"text":165,"refs":168},"ci","block",{"fa":166,"en":167},"حساسیت به اجزا؛ همراه داروهای حاوی ریلپی‌ویرین.","Hypersensitivity to any component; with rilpivirine-containing products.",[169],{"source":34,"section":170},"4",{"id":172,"severity":164,"rule":173,"text":175,"refs":178},"under-1",{"maxAge":174},{"value":5,"unit":54},{"fa":176,"en":177},"زیر ۱ سال مؤثر نبوده است.","Not effective under 1 year of age.",[179],{"source":34,"section":180},"8.4",[],[],[],[],{"status":186,"reviewer":129,"date":129},"unverified",[188,193,197,200,205,210],{"regimen":46,"formulation":23,"input":189,"expect":192},{"ageYears":190,"weightKg":191},40,70,{"perDose":28},{"regimen":70,"formulation":37,"input":194,"expect":195},{"ageYears":190,"weightKg":191},{"perDay":196},60,{"regimen":92,"formulation":37,"input":198,"expect":199},{"ageYears":190,"weightKg":191},{"perDose":40},{"regimen":114,"formulation":23,"input":201,"expect":204},{"ageYears":202,"weightKg":203},6,20,{"perDose":28},{"regimen":114,"formulation":37,"input":206,"expect":209},{"ageYears":207,"weightKg":208},11,35,{"perDose":40},{"regimen":143,"formulation":23,"input":211,"expect":213},{"ageYears":83,"weightKg":212},50,{"perDose":28},[215],"A02BC03",{"status":217,"forms":218,"refs":235},"registered",[219,223,227,231],{"code":220,"en":221,"fa":222},"12904","LANSOPRAZOLE 15MG  TAB","قرص لانسوپرازول ۱۵ میلی‌گرم",{"code":224,"en":225,"fa":226},"06770","LANSOPRAZOLE 15MG CAP","کپسول لانسوپرازول ۱۵ میلی‌گرم",{"code":228,"en":229,"fa":230},"06222","LANSOPRAZOLE 30MG CAP","کپسول لانسوپرازول ۳۰ میلی‌گرم",{"code":232,"en":233,"fa":234},"12720","LANSOPRAZOLE 30MG TAB","قرص لانسوپرازول ۳۰ میلی‌گرم",[236],{"source":237,"section":238,"url":239},"darooyab-generic","G-2600\u002FLansoprazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-2600\u002FLansoprazole",[241,245,249,252,255,258],{"kind":242,"url":243,"label":244},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=077255","ANDA077255",{"kind":246,"url":247,"label":248},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=427cf924-be17-47dc-8f77-115fa2f3fe17","FDA Lansoprazole",{"kind":250,"url":251,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa695020.html",{"kind":250,"url":253,"label":254},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601067.html","Lansoprazole, Clarithromycin, and Amoxicillin",{"kind":256,"url":257,"label":215},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A02BC03",{"kind":259,"url":239,"label":8},"darooyab",{"pregnancy":261,"lactation":270,"pediatric":278,"geriatric":285},{"level":262,"text":263,"quote":266,"refs":267},"caution",{"fa":264,"en":265},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Available data from published observational studies overall do not indicate an association of adverse pregnancy outcomes with lansoprazole treatment (see Data) .",[268],{"source":34,"section":269},"8.1",{"level":262,"text":271,"quote":274,"refs":275},{"fa":272,"en":273},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There is no information regarding the presence of lansoprazole in human milk, the effects on the breastfed infant, or the effects on milk production.",[276],{"source":34,"section":277},"8.2",{"level":262,"text":279,"quote":282,"refs":283},{"fa":280,"en":281},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of lansoprazole have been established in pediatric patients one year to 17 years of age for short-term treatment of symptomatic GERD and erosive esophagitis.",[284],{"source":34,"section":180},{"level":262,"text":286,"quote":289,"refs":290},{"fa":287,"en":288},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the total number of patients (n=21,486) in clinical studies of lansoprazole, 16% of patients were aged 65 years and over, while 4% were 75 years and over.",[291],{"source":34,"section":292},"8.5",{"kind":294,"refs":295,"id":244},"ANDA",[296],{"source":34,"section":297},"SPL approval \u002F marketing category",1792191866902]