Levonorgestrel intrauterine system 52 mg
سیستم داخل رحمی لوونورژسترل (میرنا)
🚻 Genito Urinary System And Sex HormonesIntrauterine progestin
Market / country: 🇺🇸 USA
Mirena (US)
🧮 Dose calculator
Contraception (combined pill) · Regimen source: FDA Mirena · 1FDA Mirena · 2.1
- • Inserted by a trained provider with strict asepsis; re-examine at 4–6 weeks and then yearly. FDA Mirena · 2.2FDA Mirena · 2.3
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Pregnancy or suspicion; emergency contraception; uterine anomaly distorting the cavity; acute or prior PID; postpartum endometritis or infected abortion in the past 3 months; breast or progestin-sensitive cancer; uterine or cervical malignancy; acute liver disease or liver tumour. FDA Mirena · 4
Warnings
- • Ectopic pregnancy; risks of intrauterine pregnancy with the device; sepsis; pelvic infection; perforation; expulsion; ovarian cysts; bleeding pattern changes. FDA Mirena · 5
Formulations
- One T-shaped system with 52 mg levonorgestrel (about 21 mcg/day at first) — intrauterine system (IUS) 🇺🇸 USA FDA Mirena · 3
👥 Special populations
- 🤰 PregnancyContraindicated
Label: contraindicated in pregnancy. FDA Mirena · 4
“The use of Mirena is contraindicated when one or more of the following conditions exist: • Pregnancy or suspicion of pregnancy [see Warnings and Precautions ( 5.2 ), Use in Specific Populations ( 8.1 )] • For use as post-coital contraception (emergency contraception) • Congenital or acquired uterine anomaly including …”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Mirena · 8.2
“Risk Summary Published studies report the presence of LNG in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Mirena · 8.4
“Safety and efficacy of Mirena have been established in women of reproductive age.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Mirena · 8.5
“Mirena has not been studied in women over age 65 and is not approved for use in this population.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Mirena · 8.3
“Return to Fertility After Discontinuing Mirena In two studies, return to fertility was investigated in a total of 229 women who desired pregnancy after study discontinuation and provided follow-up information.”
🔗 Reference links
- FDA (approval record)NDA021225
- DailyMed (FDA label)FDA Mirena
- MedlinePlus (NIH)Levonorgestrel Intrauterine System
- WHO ATC/DDDG02BA03
- Darooyab (Iran)Levonorgestrel
🇮🇷 Registered in Iran Darooyab · G-3293/Levonorgestrel
Dosage forms with Iranian generic codes, per Darooyab.
- 00750 · LEVONORGESTREL 0.03MG TAB · قرص لوونورژسترل ۰٫۰۳ میلیگرم
- 02441 · LEVONORGESTREL 0.75MG TAB · قرص لوونورژسترل ۰٫۷۵ میلیگرم
- 16870 · LEVONORGESTREL 1.5MG TAB · قرص لوونورژسترل ۱٫۵ میلیگرم
- 08959 · LEVONORGESTREL 52MG IUD · آییودی لوونورژسترل ۵۲ میلیگرم
- 01572 · LEVONORGESTREL 6X36MG IMPLANT · ایمپلنت لوونورژسترل ۶ X ۳۶ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Mirena · 3FDA Mirena · 1FDA Mirena · 2.1FDA Mirena · 2.2FDA Mirena · 2.3FDA Mirena · 4FDA Mirena · 5FDA Mirena · 8.2FDA Mirena · 8.4FDA Mirena · 8.5FDA Mirena · 8.3FDA Mirena · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3293/Levonorgestrel
- Clinical review⚠ Unverified