Levothyroxine
لووتیروکسین
🧬 Systemic Hormonal Preparations, Excl. Sex Hormones And InsulinsThyroid hormone
Market / country: 🇺🇸 USA
Synthroid (US)
🧮 Dose calculator
Hypothyroidism · Regimen source: FDA Levothyroxine · 2.3, Table 2
- • Starting daily dose; titrate every 2 weeks by TSH or free T4. Empty stomach, 30–60 min before breakfast. FDA Levothyroxine · 2.3FDA Levothyroxine · 2.1
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Uncorrected adrenal insufficiency. FDA Levothyroxine · 4
Warnings
- • Boxed warning: not for obesity or weight loss. FDA Levothyroxine · WARNING: NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSS
Formulations
- 25 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 50 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 75 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 88 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 100 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 112 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 125 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 137 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 150 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 175 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
- 200 mcg tablet — tablet 🇺🇸 USA FDA Levothyroxine · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Levothyroxine · 8.1
“Risk Summary The clinical experience, including data from postmarketing studies, in pregnant women treated with oral levothyroxine to maintain euthyroid state have not reported increased rates of major birth defects, miscarriages, or other adverse maternal or fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Levothyroxine · 8.2
“Risk Summary Published studies report that levothyroxine is present in human milk following the administration of oral levothyroxine.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Levothyroxine · 8.4
“Levothyroxine sodium is indicated in patients from birth to less than 17 years of age: As a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Levothyroxine · 8.5
“… levothyroxine sodium at less than the full replacement dose [see Dosage and Administration ( 2.3 ) and Warnings and Precautions ( 5.2 )].”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA211417
- DailyMed (FDA label)FDA Levothyroxine
- MedlinePlus (NIH)Levothyroxine
- WHO ATC/DDDH03AA01
- Darooyab (Iran)Levothyroxine-Sodium
🇮🇷 Registered in Iran Darooyab · G-3412/Levothyroxine-Sodium
Dosage forms with Iranian generic codes, per Darooyab.
- 07938 · LEVOTHYROXINE SODIUM 0.025MG TAB · قرص لووتیروکسین سدیم ۰٫۰۲۵ میلیگرم
- 02067 · LEVOTHYROXINE SODIUM 0.05MG TAB · قرص لووتیروکسین سدیم ۰٫۰۵ میلیگرم
- 09586 · LEVOTHYROXINE SODIUM 0.075MG TAB · قرص لووتیروکسین سدیم ۰٫۰۷۵ میلیگرم
- 16848 · LEVOTHYROXINE SODIUM 0.15MG TAB · قرص لووتیروکسین سدیم ۰٫۱۵ میلیگرم
- 00751 · LEVOTHYROXINE SODIUM 0.1MG TAB · قرص لووتیروکسین سدیم ۰٫۱ میلیگرم
- 16634 · LEVOTHYROXINE SODIUM 500MCG VIAL · ویال لووتیروکسین سدیم ۵۰۰ میکروگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Levothyroxine · 3FDA Levothyroxine · 2.3, Table 2FDA Levothyroxine · 2.3FDA Levothyroxine · 2.1FDA Levothyroxine · 2.3, Table 1FDA Levothyroxine · 4FDA Levothyroxine · WARNING: NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSSFDA Levothyroxine · 8.1FDA Levothyroxine · 8.2FDA Levothyroxine · 8.4FDA Levothyroxine · 8.5FDA Levothyroxine · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3412/Levothyroxine-Sodium
- Clinical review⚠ Unverified