Losartan

لوزارتان

⚠ Unverified

❤️ Cardiovascular SystemAngiotensin receptor blocker

Market / country: 🇺🇸 USA

Cozaar (US)

🧮 Dose calculator

Hypertension · Regimen source: FDA Losartan · 2.1FDA Losartan · 8.4

  • • Adjust to blood pressure; doses above 1.4 mg/kg or 100 mg/day not studied in children. FDA Losartan · 2.1

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🛡️ Safety & information

Contraindications

Warnings

Renal adjustment

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Losartan · Boxed Warning

    “WARNING: FETAL TOXICITY See full prescribing information for complete boxed warning.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Losartan · 8.2

    “Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Losartan · 8.4

    “Safety and effectiveness have not been established in pediatric patients under the age of 6 or in pediatric patients with glomerular filtration rate <30 mL/min/1.73 m 2 [see Dosage and Administration (2.1) , Clinical Pharmacology (12.3) , and Clinical Studies (14.1) ] .”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Losartan · 8.5

    “In a controlled clinical study for the reduction in the combined risk of cardiovascular death, stroke and myocardial infarction in hypertensive patients with left ventricular hypertrophy, 2857 patients (62%) were 65 years and over, while 808 patients (18%) were 75 years and over.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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