[{"data":1,"prerenderedAt":147},["ShallowReactive",2],{"drug-mebeverine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":23,"regimens":38,"contraindications":61,"warnings":80,"renal":81,"monitoring":82,"interactions":83,"review":84,"examples":87,"atc":94,"iran":96,"links":112,"populations":122},"mebeverine",1,{"fa":7,"en":8},"مبورین","Mebeverine","alimentary-metabolism",{"fa":11,"en":12},"ضداسپاسم روده","Intestinal antispasmodic",[14],{"name":15,"market":16},"Colofac","GB",[18,19,7,20,21,22],"colofac","کولوفاک","مبه ورین","دوسپاتالین","duspatalin",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":33,"refs":34},"tab-135","tablet","oral","135 mg coated tablet",{"amount":30,"unit":31,"perUnit":26,"scored":32},135,"mg",false,[16],[35],{"source":36,"section":37},"uk-smpc-colofac","2",[39],{"id":40,"disease":40,"label":41,"population":44,"type":48,"unit":31,"dose":49,"refs":51,"notes":54},"ibs",{"fa":42,"en":43},"IBS — بزرگسال: ۱۳۵ mg سه بار در روز","IBS — adults: 135 mg three times daily",{"minAge":45},{"value":46,"unit":47},18,"year","fixed",{"perDose":30,"dosesPerDay":50},3,[52],{"source":36,"section":53},"4.2",[55],{"text":56,"refs":59},{"fa":57,"en":58},"۲۰ دقیقه قبل از غذا، جویده نشود. پس از چند هفته و بهبود، دوز به‌تدریج کم شود.","20 min before meals, do not chew. After several weeks with good effect, reduce gradually.",[60],{"source":36,"section":53},[62,71],{"id":63,"severity":64,"text":65,"refs":68},"ci","block",{"fa":66,"en":67},"حساسیت به مبورین.","Hypersensitivity to mebeverine.",[69],{"source":36,"section":70},"4.3",{"id":72,"severity":64,"rule":73,"text":75,"refs":78},"child",{"maxAge":74},{"value":46,"unit":47},{"fa":76,"en":77},"در کودکان توصیه نمی‌شود.","Not recommended in children.",[79],{"source":36,"section":53},[],[],[],[],{"status":85,"reviewer":86,"date":86},"unverified",null,[88],{"regimen":40,"formulation":25,"input":89,"expect":92},{"ageYears":90,"weightKg":91},35,65,{"perDose":30,"perDay":93},405,[95],"A03AA04",{"status":97,"forms":98,"refs":107},"registered",[99,103],{"code":100,"en":101,"fa":102},"09532","MEBEVERINE 200MG ER CAP","کپسول آهسته‌رهش مبورین ۲۰۰ میلی‌گرم",{"code":104,"en":105,"fa":106},"00787","MEBEVERINE HCL 135MG TAB","قرص مبورین هیدروکلراید ۱۳۵ میلی‌گرم",[108],{"source":109,"section":110,"url":111},"darooyab-generic","G-2612\u002FMebeverine","https:\u002F\u002Fwww.darooyab.ir\u002FG-2612\u002FMebeverine",[113,116,118],{"kind":114,"url":115,"label":95},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A03AA04",{"kind":117,"url":111,"label":8},"darooyab",{"kind":119,"url":120,"label":121},"emc","https:\u002F\u002Fwww.medicines.org.uk\u002Femc\u002Fproduct\u002F102499\u002Fsmpc","UK SmPC Colofac",{"pregnancy":123,"lactation":132,"pediatric":139},{"level":124,"text":125,"quote":128,"refs":129},"caution",{"fa":126,"en":127},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","and lactation Pregnancy There are no or limited amounts of data from the use of mebeverine in pregnant women.",[130],{"source":36,"section":131},"4.6",{"level":124,"text":133,"quote":136,"refs":137},{"fa":134,"en":135},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","The excretion of mebeverine in milk has not been studied in animals.",[138],{"source":36,"section":131},{"level":140,"text":141,"quote":144,"refs":145},"not-established",{"fa":142,"en":143},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Paediatric Population Mebeverine 135 mg tablets are not recommended for use in children and adolescents below 18, due to insufficient data on safety and efficacy.",[146],{"source":36,"section":53},1792440722778]