Meloxicam

ملوکسیکام

⚠ Unverified

🦴 Musculo-Skeletal SystemNSAID

Market / country: 🇺🇸 USA

Mobic (US)

🧮 Dose calculator

Osteoarthritis · Regimen source: FDA Meloxicam · 2.2

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity; history of asthma, urticaria or allergic-type reaction after aspirin or other NSAIDs; in the setting of CABG surgery. FDA Meloxicam · 4
  • ⚠️ Boxed warning: risk of serious cardiovascular thrombotic events and GI bleeding, ulceration and perforation. FDA Meloxicam · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Meloxicam · 8.1

    “Clinical Considerations Fetal/Neonatal Adverse Reactions Premature Closure of Fetal Ductus Arteriosus: Avoid use of NSAIDs in women at about 30 weeks gestation and later in pregnancy, because NSAIDs, including meloxicam, can cause premature closure of the fetal ductus arteriosus (see Data).”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Meloxicam · 8.2

    “Risk Summary There are no human data available on whether meloxicam is present in human milk, or on the effects on breastfed infants, or on milk production.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Meloxicam · 8.4

    “The safety and effectiveness of meloxicam in pediatric JRA patients from 2 years to 17 years of age has been evaluated in three clinical trials [see Dosage and Administration ( 2.3 ), Adverse Reactions ( 6.1 ) and Clinical Studies ( 14.2 )].”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Meloxicam · Boxed Warning

    “Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events ( 5.2 ) Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial …”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Meloxicam · 8.3

    “Infertility Females Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including meloxicam, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women.”

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